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Trulance Approved for Chronic Constipation

Posted 1 day 19 hours ago by Drugs.com

FRIDAY, Jan. 20, 2017 – Trulance (plecanatide) has been approved by the U.S. Food and Drug Administration to treat persistent constipation of unknown (idiopathic) cause in adults. Some 42 million people in the United States are affected by constipation, according to the National Institutes of Health. Once-daily Trulance is designed to stimulate the upper gastrointestinal tract to secrete fluid and "support regular bowel function," the FDA said in a news release. The oral drug was evaluated in two 12-week clinical studies involving a total of 1,775 adults with chronic constipation. Diarrhea was the most common side effect. If diarrhea becomes severe, users should stop taking Trulance and contact a doctor, the FDA advised. Trulance is produced by New York City-based Synergy Pharmaceuticals. More information Visit the FDA to learn more about this approval. Read more

Related support groups: Diarrhea, Constipation, Constipation - Chronic, Constipation - Drug Induced, Diarrhea, Acute, Fecal Impaction, Trulance, Plecanatide

Health Tip: Concerned About Constipation?

Posted 11 days ago by Drugs.com

-- Constipation occurs when bowel movements happen infrequently or are difficult to pass. Sometimes, lifestyle changes can curb constipation, but other times the condition signals something more serious. The Cleveland Clinic says to see a doctor if: It isn't "normal" for you to be constipated. You notice any blood in your stools. You lose weight without trying. It becomes very painful to pass a bowel movement. You are constipated for an extended period. Read more

Related support groups: Constipation, Colonoscopy, Constipation - Chronic, Colorectal Cancer, Constipation - Acute

Constipation, Kidney Disease May Be Linked, New Research Shows

Posted 11 Nov 2016 by Drugs.com

THURSDAY, Nov. 10, 2016 – People with constipation are more likely to develop kidney disease, a new study finds. The discovery suggests kidney problems might be prevented or treated by managing constipation, according to researchers at the University of Tennessee Health Science Center and Memphis VA Medical Center. They studied the medical records of 3.5 million U.S. veterans with normal kidney function. They were tracked from 2004 to 2006, and followed through 2013. Those with constipation were 13 percent more likely than patients without constipation to develop chronic kidney disease and 9 percent more likely to experience kidney failure. The risk was even higher for those whose constipation was more severe. The study did not prove that constipation causes kidney disease or failure, however. Instead, "Our findings highlight the plausible link between the gut and the kidneys and ... Read more

Related support groups: Constipation, Renal Failure, Constipation - Chronic, Chronic Kidney Disease, Constipation - Acute, Constipation - Drug Induced, Fecal Impaction, Renal and Genitourinary Disorders

The Scoop About Healthy Poop

Posted 25 Oct 2016 by Drugs.com

TUESDAY, Oct. 25, 2016 – Your bowel movements can offer important clues about your health, a doctor says. If bowel movements feel comfortable, then it's likely all is well, said Dr. Gabriel Neal, a family medicine doctor and clinical assistant professor at Texas A&M College of Medicine. "Normal bowel movements are relatively soft but dense. They should be any shade of brown or green," Neal said in a college news release. Viruses and bacteria in the intestinal tract can cause stool discoloration, diarrhea or blood in the stool. The color of the blood can help your doctor pinpoint the location of the infection. "If an infection is in the lower intestines or colon, then the blood in your stool is going to be red. If you find black blood, then the blood has oxidized and is from higher up in your digestive tract, such as the stomach or upper intestines," Neal said. People with gallbladder ... Read more

Related support groups: Diarrhea, Constipation, Crohn's Disease, Constipation - Chronic, Gastrointestinal Disorders, Gallbladder Disease, Inflammatory Bowel Disease, Constipation - Acute, Diarrhea, Chronic, Diarrhea, Acute, Infectious Diarrhea

Can Acupuncture Ease Severe Constipation?

Posted 12 Sep 2016 by Drugs.com

MONDAY, Sept. 12, 2016 – People with severe chronic constipation may get relief from a more modern type of acupuncture, new research suggests. After eight weeks of treatment with electroacupuncture – acupuncture involving electrical stimulation – study participants experienced significant symptom and quality-of-life improvements, the study found. Electroacupuncture uses thin needles inserted beneath the skin that are attached to a device that sends electric pulses into the body. The study findings suggest a safe and effective option for difficult-to-treat patients, several gastroenterologists said. "It is heartening to see such rigorously tested alternative therapies, since so many of them are administered without any evidence to support them," said Dr. Christopher Andrews. He's a clinical associate professor in the gastroenterology division at University of Calgary Cumming School of ... Read more

Related support groups: Constipation, Constipation - Chronic, Constipation - Acute, Constipation - Drug Induced

Health Tip: Laxatives Have Side Effects

Posted 8 Jun 2016 by Drugs.com

-- Laxatives can have unpleasant side effects, especially when overused. The American Academy of Family Physicians says possible problems associated with laxative use include: Abdominal cramps or nausea. Gas, diarrhea or bloating. Electrolyte imbalance, which can affect the muscles, nerves and organs. Those most at risk include children and people with kidney disease or diabetes. Muscle weakness or muscle spasms. Fatigue, confusion, headache or vomiting. Read more

Related support groups: Peri-DS, Constipation, MiraLax, Dulcolax, Magnesium Citrate, Constipation - Chronic, Lactulose, Suprep, Polyethylene Glycol 3350, Metamucil, Milk of Magnesia, Bisacodyl, Fleet Enema, MoviPrep, Epsom Salt, Constipation - Acute, Senokot, Senna, Colace, Docusate

Health Tip: Your Child's Bowel Function

Posted 25 Aug 2015 by Drugs.com

-- Every child has different bowel habits, but certain signs may indicate a medical problem. The University of Michigan Health System says parents should visit a doctor if: The child is constipated for longer than a week, or the child's bowel movements are painful and require more than normal pushing. The child has blood in the stool, or has hemorrhoids. The child has a leaking soft stool between bowel movements. The child is vomiting or has a swollen belly. Read more

Related support groups: Constipation, Constipation - Chronic, Hemorrhoids, Constipation - Acute, Infectious Gastroenteritis, Traveler's Diarrhea

Health Tip: Should I Talk to my Doctor About Gas?

Posted 10 Aug 2015 by Drugs.com

-- While everyone has intestinal gas, some people have severe bloating that causes discomfort and other problems. The Mayo Clinic mentions these warning signs that you may need to see a doctor: Intestinal gas that is persistent and severe. Intestinal gas that occurs with vomiting. Long-term diarrhea, bloody stool or constipation. Weight loss for no apparent reason. Heartburn. Read more

Related support groups: GERD, Diarrhea, Constipation, Gas, Weight Loss, Abdominal Distension, Colitis, Indigestion, Constipation - Chronic, Hemorrhoids, Gastrointestinal Disorders, Inflammatory Bowel Disease, Duodenitis/Gastritis, Constipation - Acute, Diarrhea, Chronic, Anal Fissure and Fistula, Diarrhea, Acute, Infectious Diarrhea, Functional Gastric Disorder, Acute Abdomen

Experts Issue Guidelines for Treating Irritable Bowel Syndrome

Posted 8 Aug 2014 by Drugs.com

FRIDAY, Aug. 8, 2014 – Newly released guidelines for the treatment of irritable bowel syndrome and a type of constipation known as chronic idiopathic constipation reveal a number of proven treatments for these two common conditions. "There's a greater variety of approaches which reflect a greater understanding of the disorders," said guidelines co-author Dr. Eamonn Quigley, chief of the division of gastroenterology and hepatology at Houston Methodist Hospital. "We now have a better opportunity to improve the lives of our patients," Quigley said. The guidelines are published in the August issue of the American Journal of Gastroenterology. An estimated 5 percent to 15 percent of the world's population has irritable bowel syndrome, a condition that can cause symptoms such as abdominal pain, diarrhea or constipation, cramping and bloating, and gas. It can affect people at any age but is ... Read more

Related support groups: Irritable Bowel Syndrome, Linzess, MiraLax, Dulcolax, Constipation - Chronic, Lactulose, Amitiza, Polyethylene Glycol 3350, Metamucil, Xifaxan, Bisacodyl, Rifaximin, Psyllium, Linaclotide, Duphalac, Konsyl, GlycoLax, Dulcolax Laxative, ClearLax, Kristalose

Constipation Treatments Not Equally Effective: Review

Posted 28 Jan 2013 by Drugs.com

MONDAY, Jan. 28 – Some treatments are more effective than others for relieving constipation in seniors, according to a new review. And laxatives aren't always enough, researchers say. Constipation is common in seniors and can have serious health consequences and affect quality of life. Excessive straining in frail elderly people can cause them to faint and put them at risk of injury or falling, or restrict blood flow to the heart and brain. Chronic constipation can lead to fecal impaction, a large lump of hard stool that remains stuck in the rectum. Fecal impaction can cause nausea, pain and loss of appetite. "Given the growing proportion of older adults in North America, effective management of constipation by health care professionals will be increasingly necessary," Dr. Dov Gandell, of Sunnybrook Health Sciences Centre in Toronto, and colleagues wrote in an article appearing Jan. 28 ... Read more

Related support groups: Peri-DS, Constipation, MiraLax, Dulcolax, Magnesium Citrate, Constipation - Chronic, Lactulose, Suprep, Polyethylene Glycol 3350, Metamucil, Milk of Magnesia, Bisacodyl, Fleet Enema, MoviPrep, Epsom Salt, Constipation - Acute, Senokot, Senna, Colace, Docusate

Linzess Approved for Irritable Bowel, Chronic Constipation

Posted 30 Aug 2012 by Drugs.com

THURSDAY, Aug. 30 – Linzess (linaclotide) has been approved by the U.S. Food and Drug Administration to treat forms of chronic constipation that don't respond to traditional treatment, and irritable bowel syndrome accompanied by constipation, the agency said Thursday in a news release. The National Institutes of Health estimates that some 63 million people are affected by chronic constipation, and about 15.3 million have irritable bowel syndrome (IBS), the FDA said. Linzess is taken once daily on an empty stomach, at least 30 minutes before the first meal. The most frequently noted adverse reaction is diarrhea. The drug's label contains a boxed warning that it shouldn't be taken by people aged 16 or younger, the FDA said. Linzess is produced by Cambridge, Mass.-based Ironwood Pharmaceuticals. More information Medline Plus has more about constipation. Read more

Related support groups: Constipation, Irritable Bowel Syndrome, Constipation - Chronic

FDA Approves Linzess to Treat Certain Cases of Irritable Bowel Syndrome and Constipation

Posted 30 Aug 2012 by Drugs.com

August 30,2012 – The U.S. Food and Drug Administration today approved Linzess (linaclotide) to treat chronic idiopathic constipation and to treat irritable bowel syndrome with constipation (IBS-C) in adults. According to the National Institutes of Health, an estimated 63 million people are affected by chronic constipation. Chronic idiopathic constipation is a diagnosis given to those who experience persistent constipation and do not respond to standard treatment. Additionally, an estimated 15.3 million people are affected by IBS. IBS-C is a subtype characterized mainly by abdominal pain and by hard or lumpy stools at least 25 percent of the time and loose or watery stools less than 25 percent of the time. Linzess is a capsule taken once daily on an empty stomach, at least 30 minutes before the first meal of the day. Linzess helps relieve constipation by helping bowel movements occur ... Read more

Related support groups: Constipation, Irritable Bowel Syndrome, Constipation - Chronic

Fiber Beats Other Remedies for Constipated Kids, Study Says

Posted 27 Sep 2011 by Drugs.com

TUESDAY, Sept. 27 – Many children in western countries suffer from chronic constipation, and when the going gets slow, fiber seems to beat all other non-drug remedies, new research from the Netherlands suggests. A review of nine studies with 640 children up to age 18 with functional constipation, which has no known physical cause, found that fiber supplements were somewhat better than placebos at reducing kids' abdominal pain and improving frequency and consistency of stools. Other common non-drug treatments – including prebiotics and probiotics, which help restore the digestive tract's balance of "good bacteria," increased water intake or behavioral therapy – were deemed to be of little use, a finding that puzzles some doctors. "Treatments we typically use were not, in fact, proven by these studies to be effective. I find that very difficult to believe and put into practice," said ... Read more

Related support groups: Constipation, Constipation - Chronic, Constipation - Acute, Dietary Fiber Supplementation

Experimental Drug May Help Ease Chronic Constipation

Posted 10 Aug 2011 by Drugs.com

WEDNESDAY, Aug. 10 – An experimental drug called linaclotide can help reduce the symptoms of chronic constipation, according to new research funded by the drug maker. In two randomized 12-week trials, about 21 percent of participants taking the drug had at least three spontaneous bowel movements a week, compared to no more than 6 percent of those taking placebo, the study results showed. "People who received the drug had improvement in symptoms, and the treatment was generally well-tolerated," said the study's lead author, Dr. Anthony J. Lembo, an associate professor of medicine at Harvard Medical School and director of the GI Motility Center at Beth Israel Deaconess Medical Center in Boston. The study, which was funded by Ironwood Pharmaceuticals, was published in the Aug. 11 issue of the New England Journal of Medicine. Between 12 percent and 19 percent of Americans have experienced ... Read more

Related support groups: Constipation, Constipation - Chronic

Chronic Constipation Appears to Be Increasing Among Kids

Posted 1 Nov 2010 by Drugs.com

FRIDAY, Oct. 29 – An increasing number of American children require treatment for serious and chronic bouts of constipation, according to experts. Lack of physical activity, low-fiber diets and insufficient consumption of water may be contributing to the problem, they suggest. Gastroenterologists at Johns Hopkins Children's Center reported seeing a 30 percent rise in the number of such cases between 2008 and 2009. The center has opened a new clinic to provide medical and behavioral therapy for children with the condition. It's not clear whether the increase in children requiring treatment is due to an actual rise in the number of severe cases of constipation or whether it's the result of delayed diagnosis, insufficient treatment, and referral at more advanced stages, said Dr. Maria Oliva-Hemker, director of pediatric Gastroenterology & Nutrition at Hopkins Children's. Constipation is ... Read more

Related support groups: Constipation, Constipation - Chronic

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Linzess, lactulose, Amitiza, MoviPrep, colchicine, Movantik, TriLyte, linaclotide, GoLYTELY, view more... Zelnorm, polyethylene glycol 3350 with electrolytes, PEG-3350 with Electolytes, Relistor, Duphalac, GaviLyte-G, Kristalose, lubiprostone, Colyte, Generlac, GaviLyte-C, Enulose, dong quai, methylnaltrexone, Constulose, Go-Evac, Trulance, Suclear, tegaserod, Co-Lav, GaviLyte-N, plecanatide, Cholac, Constilac, Cephulac, Chronulac, Evalose, Heptalac, naloxegol, Colonic Lavage Solution, Chronulac Syrup, NuLYTELY