Skip to Content

Join the 'Clostridial Infection' group to help and get support from people like you.

Clostridial Infection News

Related terms: Clostridium difficile-Associated Diarrhea, CDAD, CDI, Clostridium difficile Infection

Think You're Allergic to Penicillin? Check Again

Posted 17 days ago by Drugs.com

MONDAY, Feb. 6, 2017 – Many people who think they're allergic to penicillin don't really have an allergy to this antibiotic, a pediatric expert says. And anyone who thinks they have had an allergic reaction to penicillin should undergo an allergy test to ensure they really need to avoid these important drugs, Dr. Min Lee advised. She is a pediatric allergist at UT Southwestern Medical Center at Dallas. "Penicillins are some of the safest and cheapest antibiotics available, and people who are reported to be allergic often get antibiotics that are costlier and potentially more toxic," Lee said in a news release from the medical center. According to UT Southwestern researchers, 90 percent of people who have a penicillin allergy listed in their medical records didn't actually have a reaction when exposed to the medication during an allergy test. Doctors can test for a penicillin allergy in ... Read more

Related support groups: Allergic Reactions, Allergies, Allergic Rhinitis, Hay Fever, Epinephrine, Anaphylaxis, EpiPen, Adrenalin, Clostridial Infection, Nasal Polyps, Primatene Mist, Septocaine, EpiPen 2-Pak, Bupivacaine/Epinephrine, Primatene Mist Inhaler, Epinephrine/Lidocaine, Prevention of Clostridium Difficile Infection Recurrence, Articaine/Epinephrine, EpiPen Jr, Epifrin

Drug May Be New Weapon Against a 'Superbug'

Posted 25 Jan 2017 by Drugs.com

WEDNESDAY, Jan. 25, 2017 – A newly approved drug may help in the battle against Clostridium difficile – a potentially fatal "superbug" gut infection that has become a scourge in U.S. hospitals. In two clinical trials, researchers found that the drug, called bezlotoxumab (Zinplava), cut the risk of a recurrent C. difficile infection by almost 40 percent. That's important, because the gut infection commonly comes back after treatment with antibiotics – around 20 percent of the time, according to the U.S. Centers for Disease Control and Prevention. The infection can also make people seriously ill, with symptoms ranging from diarrhea to life-threatening inflammation of the colon, the CDC says. Zinplava has already been approved by the U.S. Food and Drug Administration, and it should be available early this year, according to Merck, the drug's maker. That approval was based on the ... Read more

Related support groups: Infections, Diarrhea, Bacterial Infection, Clostridial Infection, Diarrhea, Acute, Infectious Diarrhea, Prevention of Clostridium Difficile Infection Recurrence, Zinplava, Bezlotoxumab

Antibiotic Overuse Behind 'Superbug' Outbreak in U.K. Hospitals

Posted 25 Jan 2017 by Drugs.com

WEDNESDAY, Jan. 25, 2017 – Overuse of antibiotics triggered a severe diarrhea outbreak in British hospitals that began in 2006, a new study reports. Researchers analyzed hospital data related to the outbreak of Clostridium difficile, a "superbug" gut infection. The investigators concluded that reducing the use of fluoroquinolones – antibiotics such as ciprofloxacin (Cipro) and levofloxacin (Levaquin) – curbed the outbreak. "These findings are of international importance because other regions, such as North America, where fluoroquinolone prescribing remains unrestricted, still suffer from epidemic numbers of C. difficile infections," said study co-author Derrick Crook. He is a professor of microbiology at the University of Oxford in England. Overuse of fluoroquinolones enabled antibiotic-resistant C. difficile to thrive because non-resistant bugs in the gut were killed off by the ... Read more

Related support groups: Infections, Diarrhea, Bacterial Infection, Cipro, Ciprofloxacin, Levaquin, Levofloxacin, Avelox, Diarrhea, Chronic, Ofloxacin, Ciprodex, Moxifloxacin, Clostridial Infection, Diarrhea, Acute, Gatifloxacin, Norfloxacin, Infectious Diarrhea, Gemifloxacin, Ciloxan, Sparfloxacin

Study Questions 'Fecal Transplant' Treatment for Gut Infection

Posted 13 Jan 2017 by Drugs.com

FRIDAY, Jan. 13, 2017 – A single fecal transplant delivered by enema is apparently no more effective than oral antibiotics in treating recurring cases of a nasty stomach bug, a Canadian study contends. The study is the first head-to-head comparison between fecal transplant and the current standard of care of antibiotics in treating Clostridium difficile infection, the researchers said. "We thought it was important to have that comparison so we could know: How much better is it than what we're actually already doing?" said lead author Dr. Susy Hota. She's the medical director of infection prevention and control at University Health Network in Toronto. In this study, "it looks like they're working about the same," Hota said. "In half the patients, it didn't work, but in the other half, it did." Infection from C. difficile bacteria can be debilitating, triggering bouts of diarrhea and ... Read more

Related support groups: Colonoscopy, Clostridial Infection, Diagnosis and Investigation, Prevention of Clostridium Difficile Infection Recurrence

U.S. Death Toll From Infectious Diseases Unchanged: Study

Posted 22 Nov 2016 by Drugs.com

TUESDAY, Nov. 22, 2016 – The war against infectious diseases – medicine versus microbes – has been holding steady, with the U.S. death rate from these diseases about the same now as it was in 1980, new research says. But some of the specific disease threats have changed over the years, the study authors noted. Researchers found that the national death rate from infections stood at almost 46 deaths per 100,000 people in 2014. That compared with 42 per 100,000 in 1980. There were some major shifts during that time, however. The overall death rate went as high as 63 per 100,000 in 1995, owing to the HIV/AIDS epidemic, according to the study. AIDS deaths declined from then on, with the introduction of the "drug cocktails" that have turned HIV into a manageable chronic disease. But while there was progress against HIV, deaths from pneumonia and flu complications held steady over the ... Read more

Related support groups: Bacterial Infection, Influenza, Pneumonia, HIV Infection, Clostridial Infection, Viral Infection, West Nile Virus, Adjunct to Antibiotic Therapy, Prevention of Clostridium Difficile Infection Recurrence

FDA Approves Merck’s Zinplava (bezlotoxumab) to Reduce Recurrence of Clostridium difficile Infection

Posted 25 Oct 2016 by Drugs.com

KENILWORTH, N.J.--(BUSINESS WIRE) October 21, 2016 --Merck (NYSE:MRK), known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration (FDA) has approved Zinplava (bezlotoxumab) Injection 25 mg/mL. Merck anticipates making Zinplava available in first quarter 2017. Zinplava is indicated to reduce recurrence of Clostridium difficile infection (CDI) in patients 18 years of age or older who are receiving antibacterial drug treatment of CDI and are at high risk for CDI recurrence. Zinplava is not indicated for the treatment of CDI. Zinplava is not an antibacterial drug. Zinplava should only be used in conjunction with antibacterial drug treatment of CDI. CDI is caused by bacteria that produce toxins, including toxin B. Symptoms of CDI include mild-to-severe diarrhea, abdominal pain and fever. The incidence of recurrent CDI is higher in certain ... Read more

Related support groups: Clostridial Infection, Zinplava, Bezlotoxumab

If Patient in the Hospital Bed Before You Got Antibiotics -- Take Heed

Posted 10 Oct 2016 by Drugs.com

MONDAY, Oct. 10, 2016 – When a hospital patient is taking antibiotics, the next person to use the same bed may face an elevated risk of infection with the dangerous germ Clostridium difficile, a new study suggests. C. difficile, a bacterium that causes inflammation of the colon and causes life-threatening diarrhea, is found in U.S. hospitals. Scientists have known that antibiotic use can contribute to the germ's spread, but this new report says it's not just the patient taking the medication who's at risk. Because the germ spores can persist, patients later assigned to the same hospital bed may have increased odds of getting C. difficile, researchers found. "This study provides evidence that there is a herd effect with antibiotics," said lead researcher Dr. Daniel Freedberg, a gastroenterologist at Columbia University Medical Center in New York City. "In other words, antibiotics have ... Read more

Related support groups: Clostridial Infection

Frozen as Good as Fresh for Fecal Transplant: Study

Posted 12 Jan 2016 by Drugs.com

TUESDAY, Jan. 12, 2016 – Researchers say they have verified the effectiveness of a quicker way to rid people of recurring C. difficile bacterial infection. A new clinical trial has shown that frozen stool samples work just as well as freshly donated samples when treating a tough C. difficile infection through a procedure called fecal transplantation. Doctors have used frozen stool samples to treat C. difficile for a couple of years, because the prepackaged samples allow for much easier and swifter treatment than identifying and screening a fresh donor, said lead author Dr. Christine Lee, director of the microbiology residency program at McMaster University in Ontario, Canada. "Donor screening can take one to two weeks," Lee said. "If a person requires fecal transplant right away, then that's not possible." The clinical trial showed that patients do not pay a price for the convenience ... Read more

Related support groups: Diarrhea, Bowel Preparation, Gastrointestinal Disorders, Diarrhea, Chronic, Clostridial Infection, Diarrhea, Acute, Diagnosis and Investigation, Fecal Incontinence

Post-Op Bacterial Infection Raises Odds for Complications, Death

Posted 25 Nov 2015 by Drugs.com

WEDNESDAY, Nov. 25, 2015 – People recuperating from surgery are much more likely to die or develop complications if they become infected with a dangerous diarrhea-causing bacteria, a new study suggests. Patients at VA hospitals who contracted Clostridium difficile following surgery were five times more likely to die and 12 times more likely to suffer a complication of the heart, lung, kidneys or nervous system, according to findings published online Nov. 25 in the journal JAMA Surgery. "C. difficile infection is a big hit to take for people who are already behind the eight-ball," said Dr. Brian Zuckerbraun, a surgeon at the VA Pittsburgh Healthcare System who co-wrote an accompanying editorial. "It's just a big insult to their system, when they are vulnerable." C. difficile is a tough and opportunistic bacteria that can invade the intestines of people whose gut bacteria have been wiped ... Read more

Related support groups: Infections, Surgery, Bacterial Infection, Bacterial Skin Infection, Clostridial Infection, Bacteremia

Review Finds Fecal Transplants Work Well But Need Tight Regulation

Posted 21 Oct 2015 by Drugs.com

WEDNESDAY, Oct. 21, 2015 – The growing use of fecal transplants needs to be carefully controlled, experts say. The therapy is increasingly being used to treat people with life-threatening intestinal infections, such as those caused by the bacterium Clostridium difficile. The procedure involves transferring fecal matter from a healthy donor into the intestine of a patient so that healthy bacteria can re-colonize the bowel. Researchers analyzed available evidence and found that fecal transplants were 85 percent successful in treating patients, compared with 20 percent for standard antibiotic treatment. A recent clinical trial was halted early because fecal transplantation proved so effective, with a 90 percent success rate compared to 26 percent for powerful antibiotics, the researchers noted. After more than 7,000 fecal transplants, few harmful effects have been reported and the ... Read more

Related support groups: Obesity, Diabetes, Type 2, Irritable Bowel Syndrome, Colitis, Clostridial Infection, Pseudomembranous Colitis

Non-Antibiotic Medicine May Fight Drug-Resistant 'Superbug'

Posted 23 Sep 2015 by Drugs.com

WEDNESDAY, Sept. 23, 2015 – A new mouse study suggests that a drug with a known safety record in humans might be a new weapon in the fight against the potentially deadly intestinal infection known as C. difficile. The drug is called ebselen, and it was well-tolerated in humans when tested as a possible treatment in a variety of clinical trials, including for stroke and bipolar disorder. Although ebselen has never been approved as a treatment for any condition in humans, the current research team thought the drug might help prevent the spread of infection in people with C. difficile. When the researchers gave ebselen to infected mice, the drug appeared to knock out the toxic activity of C. difficile without inflicting the collateral damage on good bacteria that's normally associated with antibiotic treatment, the study reported. The results were "very encouraging," said study senior ... Read more

Related support groups: Clostridial Infection

Better Control of Drug-Resistant Germs Could Save Thousands of Lives: CDC

Posted 4 Aug 2015 by Drugs.com

TUESDAY, Aug. 4, 2015 – An immediate, focused effort to halt the spread of antibiotic-resistant germs could save tens of thousands of lives and prevent hundreds of thousands of new infections over the next five years, a new government report suggests. As many as 37,000 lives could be saved, and 619,000 new infections prevented, if community health departments and health care facilities form tight support networks to quickly identify and address emerging outbreaks of antibiotic-resistant bacteria, said report author Dr. John Jernigan. He directs the Office of HAI (Health care-Associated Infections) Prevention Research and Evaluation at the U.S. Centers for Disease Control and Prevention. "When health care facilities and health departments in a community work together to share information about resistance, and then use that information to guide and target prevention efforts, then we ... Read more

Related support groups: Infections, Amoxicillin, Metronidazole, Doxycycline, Bacterial Infection, Clindamycin, Azithromycin, Bactrim, Cipro, Ciprofloxacin, Augmentin, Levaquin, Flagyl, Zithromax, Trimethoprim, Sulfamethoxazole, Nitrofurantoin, Erythromycin, Minocycline, Nystatin

Recent Hospitalization Might Raise Blood Infection Risk, Study Says

Posted 3 Jun 2015 by Drugs.com

WEDNESDAY, June 3, 2015 – A routine hospital stay may put older adults at risk for a potentially deadly condition called sepsis, according to a new study. Sepsis is a catastrophic, whole-body response to infection, according to the researchers. The study looked at data from nearly 11,000 older Americans. Over 12 years, there were 43,000 hospitalizations. The researchers found people were three times more likely to develop sepsis within three months after leaving the hospital than at any other time. The analysis also showed that the risk of sepsis three months after a hospital stay was 30 percent higher for those who received care for any type of infection. The risk of sepsis three months after hospitalization was 70 percent higher for those who had an intestinal infection caused by Clostridium difficile (or C. difficile) bacteria, the study revealed. One in 10 C. difficile infection ... Read more

Related support groups: Sepsis, Clostridial Infection, Wound Sepsis

Outbreaks of Gut 'Superbug' More Common in Northeast: Study

Posted 5 May 2015 by Drugs.com

TUESDAY, May 5, 2015 – Infections with the superbug known as Clostridium difficile have been the most prevalent in the Northeast during the past decade, new U.S. research shows. University of Texas researchers looked at slightly more than 2 million cases of infection with the germ, which causes colon inflammation and life-threatening diarrhea. The bug causes more health care-related infections in U.S. hospitals than any other, according to the U.S. Centers for Disease Control and Prevention. The findings were published in the May issue of the American Journal of Infection Control. C. difficile costs as much as $4.8 billion in estimated extra health care costs per year, according to CDC estimates. Roughly half a million infections occurred in 2011, killing 29,000 patients within a month of their diagnosis, according to the agency. The University of Texas researchers found the Northeast ... Read more

Related support groups: Infections, Clostridial Infection

'Good' Bacteria Might Fight Common Hospital Infection: Study

Posted 5 May 2015 by Drugs.com

TUESDAY, May 5, 2015 – Researchers may have found a new way to combat a stubborn and potentially deadly gut infection: a friendly version of the culprit bacteria itself. The infection, caused by the bug Clostridium difficile, is a common scourge in hospitals. And experts say the findings, published May 5 in the Journal of the American Medical Association, are important. Toxic strains of C. difficile bacteria cause diarrhea, abdominal cramps and, in some cases, severe inflammation of the colon. The infection commonly strikes people during or after a hospital stay – usually those who've had a long course of antibiotics or have a weakened immune system. C. difficile infections are at an all-time high in U.S. hospitals, said lead researcher Dr. Dale Gerding, a professor of medicine at Loyola University Chicago Stritch School of Medicine. A recent U.S. government report said almost half a ... Read more

Related support groups: Acidophilus, Clostridial Infection, Florastor, VSL#3, Lactobacillus Acidophilus, Flora-Q, Floranex, Probiotic Formula, Florajen3, Flora-Q 2, Bacid, Saccharomyces Boulardii Lyo, Bio-K+, Florajen, Restora, Brewer's Yeast, Florastor Kids, Align, BD Lactinex, Lactobacillus Rhamnosus Gg

Page 1 2 3 Next

Ask a Question

Further Information

Related Condition Support Groups

Prevention of Clostridium Difficile Infection Recurrence, Infections

Related Drug Support Groups

metronidazole, Flagyl, vancomycin, Acidophilus, Penicillin VK, Metro, Flagyl IV, penicillin v potassium, Vancocin, view more... Dificid, lactobacillus acidophilus, Flora-Q, fidaxomicin, Flora-Q 2, Vancocin HCl, Florajen, RisaQuad, Risa-Bid, RisaQuad 2, Pfizerpen, Bacid (LAC), Intestinex, Lacto-Key-600, Lyphocin, Flagyl 375, penicillin g potassium, penicillin g sodium, Metro IV, Protostat, Novaflor, Vancocin HCl Pulvules, Metryl, Superdophilus