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Related terms: Clostridium difficile-Associated Diarrhea, CDAD, CDI, Clostridium difficile Infection

CutisPharma Announces FDA Approval of Firvanq (vancomycin) for Treatment of Clostridium Difficile Associated Diarrhea and Staphylococcus Aureus Colitis

Posted 30 Jan 2018 by Drugs.com

WILMINGTON, Mass. (Jan. 29, 2018) – CutisPharma announced today that the US Food and Drug Administration (FDA) has approved Firvanq (vancomycin hydrochloride) for oral solution, for the treatment of Clostridium difficile associated diarrhea and enterocolitis caused by Staphylococcus aureus, including methicillin-resistant strains. “We are pleased to announce the FDA approval of Firvanq,” said Nea ...

The Neighborhood Sandbox: A Breeding Ground for Germs

Posted 7 Jul 2017 by Drugs.com

FRIDAY, July 7, 2017 – Kids love to play in sandboxes, and it helps them develop motor and social skills. But have you ever considered what kind of germs might be lurking in that communal sand? Sandboxes can be breeding grounds for bacteria, parasites and other infectious germs, whether brought in by animals using them as litter boxes or by kids interacting with other kids, researchers say. Dr. ...

Recurring Intestinal Infections on the Rise in U.S.: Study

Posted 7 Jul 2017 by Drugs.com

FRIDAY, July 7, 2017 – Recurring Clostridium difficile intestinal infections are rising sharply in the United States, researchers warn. These infections sicken about 500,000 people a year, cause tens of thousands of deaths, and cost the U.S. health care system about $5 billion, according to investigators at the University of Pennsylvania. C. difficile causes diarrhea, severe gut inflammation and ...

'Good' Donor Bacteria Can Last Long Term in Stool Transplant Patients

Posted 16 Jun 2017 by Drugs.com

FRIDAY, June 16, 2017 – Researchers say their small study offers the first proof that therapeutic donor microbes remain for months or years in patients who've undergone stool transplants. Medically known as "fecal microbiota transplantation" (FMT), the procedure is used to treat severe diarrhea and colitis caused by repeated Clostridium difficile infections, the researchers explained. FMT is an ...

U.S. Hospitals Still Prescribe Too Many Antibiotics: Study

Posted 15 Jun 2017 by Drugs.com

THURSDAY, June 15, 2017 – About 20 percent of U.S. hospital patients who receive antibiotics experience side effects from the drugs, researchers report. The new study included nearly 1,500 hospitalized adults who were prescribed antibiotics. The findings revealed that one-fifth of those who experienced antibiotic-related side effects didn't require the drugs in the first place. The results add ...

Study Suggests Heartburn Meds-Superbug Infections Link

Posted 27 Mar 2017 by Drugs.com

MONDAY, March 27, 2017 – Patients who take certain heartburn medications may be more likely to suffer recurrent bouts of a common "superbug" infection, a new study suggests. Proton pump inhibitors, such as Prilosec, Prevacid and Nexium, or so-called H2 blockers, such as Zantac, Pepcid and Tagamet, were linked to a 50 percent increased risk of developing multiple Clostridium difficile infections, ...

Many Americans Unaware of 'Superbug' Threat: Poll

Posted 27 Feb 2017 by Drugs.com

MONDAY, Feb. 27, 2017 – Antibiotic-resistant "superbugs" are a major public health threat, but most Americans are clueless about the dangers, a new HealthDay/Harris Poll shows. More than two-thirds of U.S. adults know "little" or "nothing" about so-called superbugs – bacterial infections that are resistant to many or all antibiotics. And around half believe, incorrectly, that antibiotics work ...

Think You're Allergic to Penicillin? Check Again

Posted 6 Feb 2017 by Drugs.com

MONDAY, Feb. 6, 2017 – Many people who think they're allergic to penicillin don't really have an allergy to this antibiotic, a pediatric expert says. And anyone who thinks they have had an allergic reaction to penicillin should undergo an allergy test to ensure they really need to avoid these important drugs, Dr. Min Lee advised. She is a pediatric allergist at UT Southwestern Medical Center at ...

Drug May Be New Weapon Against a 'Superbug'

Posted 25 Jan 2017 by Drugs.com

WEDNESDAY, Jan. 25, 2017 – A newly approved drug may help in the battle against Clostridium difficile – a potentially fatal "superbug" gut infection that has become a scourge in U.S. hospitals. In two clinical trials, researchers found that the drug, called bezlotoxumab (Zinplava), cut the risk of a recurrent C. difficile infection by almost 40 percent. That's important, because the gut ...

Antibiotic Overuse Behind 'Superbug' Outbreak in U.K. Hospitals

Posted 25 Jan 2017 by Drugs.com

WEDNESDAY, Jan. 25, 2017 – Overuse of antibiotics triggered a severe diarrhea outbreak in British hospitals that began in 2006, a new study reports. Researchers analyzed hospital data related to the outbreak of Clostridium difficile, a "superbug" gut infection. The investigators concluded that reducing the use of fluoroquinolones – antibiotics such as ciprofloxacin (Cipro) and levofloxacin ...

Study Questions 'Fecal Transplant' Treatment for Gut Infection

Posted 13 Jan 2017 by Drugs.com

FRIDAY, Jan. 13, 2017 – A single fecal transplant delivered by enema is apparently no more effective than oral antibiotics in treating recurring cases of a nasty stomach bug, a Canadian study contends. The study is the first head-to-head comparison between fecal transplant and the current standard of care of antibiotics in treating Clostridium difficile infection, the researchers said. "We ...

U.S. Death Toll From Infectious Diseases Unchanged: Study

Posted 22 Nov 2016 by Drugs.com

TUESDAY, Nov. 22, 2016 – The war against infectious diseases – medicine versus microbes – has been holding steady, with the U.S. death rate from these diseases about the same now as it was in 1980, new research says. But some of the specific disease threats have changed over the years, the study authors noted. Researchers found that the national death rate from infections stood at almost 46 ...

FDA Approves Merck’s Zinplava (bezlotoxumab) to Reduce Recurrence of Clostridium difficile Infection

Posted 25 Oct 2016 by Drugs.com

KENILWORTH, N.J.--(BUSINESS WIRE) October 21, 2016 --Merck (NYSE:MRK), known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration (FDA) has approved Zinplava (bezlotoxumab) Injection 25 mg/mL. Merck anticipates making Zinplava available in first quarter 2017. Zinplava is indicated to reduce recurrence of Clostridium difficile infection (CDI) in ...

If Patient in the Hospital Bed Before You Got Antibiotics -- Take Heed

Posted 10 Oct 2016 by Drugs.com

MONDAY, Oct. 10, 2016 – When a hospital patient is taking antibiotics, the next person to use the same bed may face an elevated risk of infection with the dangerous germ Clostridium difficile, a new study suggests. C. difficile, a bacterium that causes inflammation of the colon and causes life-threatening diarrhea, is found in U.S. hospitals. Scientists have known that antibiotic use can ...

Frozen as Good as Fresh for Fecal Transplant: Study

Posted 12 Jan 2016 by Drugs.com

TUESDAY, Jan. 12, 2016 – Researchers say they have verified the effectiveness of a quicker way to rid people of recurring C. difficile bacterial infection. A new clinical trial has shown that frozen stool samples work just as well as freshly donated samples when treating a tough C. difficile infection through a procedure called fecal transplantation. Doctors have used frozen stool samples to ...

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