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Pradaxa Blood Thinner May Beat Warfarin After Bleeding Episode: Study

Posted 2 days 15 hours ago by Drugs.com

THURSDAY, Dec. 1, 2016 – Use of a blood thinner is routine for many heart patients, but these drugs come with a risk of episodes of excess bleeding. What, if any, anticoagulant (blood thinner) should these patients take after such episodes arise? A new study suggests that the blood thinner Pradaxa (dabigatran) may be a better choice than the standby drug warfarin in these cases. The reason: Pradaxa is less likely than warfarin to cause recurrent bleeding in patients who recently suffered a bleeding stroke or other major bleeding event, the researchers found. "Our results should encourage clinicians to seriously consider resuming anticoagulation among patients who survived a major bleeding event, particularly if the source of bleeding was identified and addressed," said study senior author Dr. Samir Saba. He's associate chief of cardiology at the University of Pittsburgh Heart and ... Read more

Related support groups: Bleeding Disorder, Warfarin, Coumadin, Ischemic Stroke, Xarelto, Pradaxa, Lovenox, Eliquis, Transient Ischemic Attack, Heparin, Rivaroxaban, Enoxaparin, Ischemic Stroke - Prophylaxis, Apixaban, Fragmin, Clexane, Arixtra, Hep-Pak, Dalteparin, Intracranial Hemorrhage

Gene Test May ID Chemo Patients at Risk of Clots: Study

Posted 1 Nov 2016 by Drugs.com

TUESDAY, Nov. 1, 2016 – Genetic testing could help identify breast cancer patients at high risk for the formation of blood clots in their veins, new research suggests. This problem, called venous thromboembolism (VTE), is a serious and potentially fatal complication that can occur during cancer treatment, particularly chemotherapy. Because breast cancer is one of the most common cancers, breast cancer patients account for a large number of cancer-related VTE cases, said study author Judith Brand. She's a postdoctoral researcher in the department of medical epidemiology and biostatistics at Karolinska Institute in Stockholm, Sweden. Venous thromboembolism is preventable through treatment with an anti-clotting drug. But side effects, such as bleeding, mean this therapy is not routinely used in patients undergoing chemotherapy, the researchers explained. The new study included more than ... Read more

Related support groups: Blood Disorders, Cancer, Warfarin, Coumadin, Breast Cancer, Xarelto, Prostate Cancer, Pradaxa, Lovenox, Eliquis, Colorectal Cancer, Lung Cancer, Heparin, Melanoma, Rivaroxaban, Enoxaparin, Apixaban, Fragmin, Clexane, Arixtra

The Pill, Hormone Therapy Safe for Women Taking Blood Thinners: Study

Posted 22 Dec 2015 by Drugs.com

TUESDAY, Dec. 22, 2015 – Women on blood thinners can also take contraceptives that contain estrogen, or hormone replacement therapy, without raising their risk for blood clots or uterine bleeding, a new Italian study finds. Currently, women diagnosed with blood clots may be advised to stop hormone therapy or use of the contraceptive pill – even if they are already on a blood thinner. The reason: Doctors are often concerned that these drug combinations might raise the patient's risk for more clots. However, "there has been no evidence to support this decision," said the study's senior author, Dr. Ida Martinelli, of the A. Bianchi Bonomi Hemophilia and Thrombosis Center in Milan. "We conducted this study to address the fear felt by both the physician and patient when making the decision to stop or continue hormone therapy in this setting," she explained in a news release from the ... Read more

Related support groups: Birth Control, Contraception, Blood Disorders, Emergency Contraception, Bleeding Disorder, Warfarin, Coumadin, Hot Flashes, Estradiol, Menopausal Disorders, Xarelto, Premarin, Pradaxa, Ethinyl Estradiol, Postcoital Contraception, Estrace, Postmenopausal Symptoms, Lovenox, Eliquis, Vagifem

Health Tip: Know Your Risk for Deep Vein Thrombosis

Posted 4 Aug 2015 by Drugs.com

-- A dangerous condition called deep vein thrombosis (DVT) occurs when a blood clot develops in a vein deep inside the body. The U.S. National Heart Lung and Blood Institute mentions these potential risk factors: Having had a previous DVT, or taking medication that thickens the blood or promotes clotting. Having had surgery, a broken bone or other injury that affects a deep vein. Having reduced blood flow to a deep vein as a result of inactivity. Typical causes are post-surgical recovery, or taking a long trip that limits your ability to move around. Being pregnant. Being treated for cancer. Having a central venous catheter. Being over the age of 60, being a smoker or being obese. Read more

Related support groups: Blood Disorders, Warfarin, Coumadin, Xarelto, Deep Vein Thrombosis (DVT), Pradaxa, Lovenox, Eliquis, Deep Vein Thrombosis, Heparin, Deep Vein Thrombosis - First Event, Deep Vein Thrombosis - Recurrent Event, Rivaroxaban, Enoxaparin, Apixaban, Deep Vein Thrombosis Prophylaxis after Knee Replacement Surgery, Fragmin, Clexane, Arixtra, Hep-Pak

How Long Do Patients With Clots in the Lung Need Blood Thinners?

Posted 7 Jul 2015 by Drugs.com

TUESDAY, July 7, 2015 – People who suffer a blood clot in the lungs with no obvious cause can ward off a new clot with extended use of blood-thinning medications, a new study shows. However, the length of time those blood thinners should be given is unclear, since their benefits wear off soon after use is discontinued, the French researchers found. The clots are called pulmonary emboli, explained one U.S. expert, Dr. Richard Hayes. "Pulmonary emboli are clots in the blood vessels to the lungs that arise from the veins of the leg or thigh," said Hayes, a cardiologist at Lenox Health in New York City. One type of clot is deep vein thrombosis (DVT), often nicknamed "economy-class syndrome" because of cases occurring after long-haul flights. In many cases, Hayes said, there's a trigger – extended bedrest, obesity, recent surgery – for the clot, but in other cases the clots seem to arise ... Read more

Related support groups: Warfarin, Coumadin, Xarelto, Pradaxa, Pulmonary Embolism, Lovenox, Eliquis, Heparin, Rivaroxaban, Pulmonary Embolism - Recurrent Event, Enoxaparin, Apixaban, Fragmin, Clexane, Arixtra, Hep-Pak, Dalteparin, Innohep, Jantoven, Dabigatran

White Men May Get Better Treatment for Abnormal Heartbeat

Posted 30 Jun 2015 by Drugs.com

TUESDAY, June 30, 2015 – Women, Hispanics and blacks are less likely than white men to receive optimal treatment for atrial fibrillation in the United States, researchers say. The study of more than a half-million Medicare patients found that women with this abnormal heart rhythm are less likely than men to get blood thinners to prevent stroke, which is a serious risk with atrial fibrillation. Women, blacks and Hispanics are also less likely to get catheter ablation, a surgical procedure that can restore the heart's normal rhythm. "Across the board, women are offered less aggressive care, particularly in cardiology," said lead researcher Dr. Prashant Bhave, a clinical assistant professor of internal medicine at University of Iowa Health Care. "There are still gaps in how patients are treated," he said. "The most important one is the difference in prescribing blood thinners. Ablation ... Read more

Related support groups: Warfarin, Coumadin, Atrial Fibrillation, Xarelto, Pradaxa, Lovenox, Eliquis, Heparin, Prevention of Thromboembolism in Atrial Fibrillation, Rivaroxaban, Enoxaparin, Apixaban, Fragmin, Clexane, Arixtra, Thromboembolic Stroke Prophylaxis, Hep-Pak, Dalteparin, Dabigatran, Innohep

Blood Thinners OK for Cancers That Spread to Brain, Study Finds

Posted 2 Jun 2015 by Drugs.com

TUESDAY, June 2, 2015 – Blood-thinning drugs are safe for treating blood clots in patients with cancer that has spread to the brain from other areas of the body, according to new research. Cancer normally increases a person's risk of blood clots, the study authors explained in a news release from the American Society of Hematology. When a cancer patient develops a clot, a blood thinner – also called an anticoagulant – is often added to the cancer treatment regimen to prevent the risk of blood clots traveling to the lungs. Such a clot can be fatal. However, if cancer spreads from other parts of the body to the brain (called brain metastases), doctors are hesitant to prescribe blood thinners because of concern they might cause bleeding in the head, which is already a risk for these patients, the study authors added. The new findings show that the use of blood thinners in these patients ... Read more

Related support groups: Cancer, Warfarin, Coumadin, Xarelto, Pradaxa, Lovenox, Eliquis, Brain Tumor, Heparin, Rivaroxaban, Enoxaparin, Apixaban, Fragmin, Clexane, Arixtra, Hep-Pak, Dalteparin, Dabigatran, Fondaparinux, Innohep

FDA Medwatch Alert: Low Molecular Weight Heparins: Drug Safety Communication - Recommendations to Decrease Risk of Spinal Column Bleeding and Paralysis

Posted 6 Nov 2013 by Drugs.com

ISSUE: The U.S. Food and Drug Administration (FDA) is recommending that health care professionals carefully consider the timing of spinal catheter placement and removal in patients taking anticoagulant drugs, such as enoxaparin, and delay dosing of anticoagulant medications for some time interval after catheter removal to decrease the risk of spinal column bleeding and subsequent paralysis after spinal injections, including epidural procedures and lumbar punctures. These new timing recommendations, which can decrease the risk of epidural or spinal hematoma, will be added to the labels of anticoagulant drugs known as low molecular weight heparins, including Lovenox and generic enoxaparin products and similar products. BACKGROUND: Epidural or spinal hematomas are a known risk of enoxaparin in the setting of spinal procedures and are already described in the Boxed Warning and the Warnings ... Read more

Related support groups: Anesthesia, Lovenox, Enoxaparin, Clexane, Clexane Forte, Lovenox HP

Irregular Heartbeat May Pose Higher Stroke Risk for Women Than Men

Posted 31 Aug 2012 by Drugs.com

FRIDAY, Aug. 31 – Women older than 75 who have a heart rhythm disorder called atrial fibrillation are 20 percent more likely to have a stroke than men in the same age group with atrial fibrillation, according to a large new study. However, researchers said the findings suggest that being a woman should not be included as an independent risk factor for stroke or blood clots, either in guidelines for treatment or risk assessment of patients with atrial fibrillation, because the difference doesn't hold for women younger than 75. The study included more than 87,000 atrial fibrillation patients in Denmark. Of those patients, more than 51 percent were female. After one year of follow-up, female patients younger than 75 did not have an increased risk of stroke, but those over age 75 had a 20 percent increased risk, the investigators found. The study was presented Sunday at the European ... Read more

Related support groups: Warfarin, Coumadin, Atrial Fibrillation, Xarelto, Pradaxa, Lovenox, Heparin, Prevention of Thromboembolism in Atrial Fibrillation, Rivaroxaban, Enoxaparin, Fragmin, Clexane, Arixtra, Hep-Pak, Dalteparin, Fondaparinux, Innohep, Jantoven, Dabigatran, Normiflo

Adding Lovenox Didn't Reduce Blood Clot Death Risk in Study

Posted 28 Dec 2011 by Drugs.com

WEDNESDAY, Dec. 28 – Severely ill hospital patients are at high risk for developing potentially fatal blood clots, and often wear compression stockings and/or take blood thinners to help lower this risk. However, adding the blood thinner Lovenox (enoxaparin) to the mix does not reduce their chances of dying from a blood clot, according to research appearing in the Dec. 29 issue of the New England Journal of Medicine. In the new study, almost 4,200 patients received Lovenox plus compression hose and more than 4,100 were given compression hose plus a placebo to lower their risk of developing a deep venous thrombosis (DVT). These blood clots tend to occur in the lower leg and thigh, where they can block blood flow and cause swelling and pain. If a clot dislodges – becoming an embolism – it can travel to the lungs or brain, resulting in organ damage and even death. After 30 days of ... Read more

Related support groups: Lovenox, Enoxaparin, Clexane, Clexane Forte, Lovenox HP

Generic Lovenox Approved for Deep Vein Thrombosis

Posted 23 Jul 2010 by Drugs.com

FRIDAY, July 23 – The first generic version of enoxaparin sodium injection (brand name: Lovenox), a blood-thinning drug designed to prevent deep vein thrombosis, has been approved by the U.S. Food and Drug Administration. The condition, abbreviated as DVT, can cause potentially deadly blot clots that form in veins deep within the body. Veins in the lower leg and thigh are most prone to the condition, the agency said in a news release. DVT-related clots have the potential to break away and travel to the lung, triggering a deadly blockage in a lung artery called a pulmonary embolism. About 100,000 cases of pulmonary embolism are reported each year in the United States, and it's the third-most common cause of death among people in the hospital, the FDA said. Lovenox, FDA-approved in 1993, is made from the blood-thinning drug heparin. The makers of generic drugs that earn the agency's ... Read more

Related support groups: Lovenox, Enoxaparin, Clexane, Clexane Forte, Lovenox HP

Many Dialysis Patients Get Wrong Blood Thinners for Angioplasty

Posted 9 Dec 2009 by Drugs.com

TUESDAY, Dec. 8 – More than one-fifth of patients on dialysis who undergo angioplasty are given blood thinners they should not be given, new research shows. As a result, these patients are subject to a higher rate of bleeding during their hospital stay and may even be at a higher risk of dying, according to a report in the Dec. 9 issue of the Journal of the American Medical Association. The drugs in question are enoxaparin (Lovenox), a low-molecular-weight heparin, and eptifibatide (Integrilin). The U.S. Food and Drug Administration (FDA) has determined that neither medication should be used in people undergoing dialysis. "The study does validate the FDA's directed labeling [of these drugs] as contraindicated, and it supports avoiding use of these drugs in dialysis patients," said study author Dr. Thomas Tsai, director of interventional cardiology at the Denver VA Medical Center and an ... Read more

Related support groups: Lovenox, Enoxaparin, Clexane, Integrilin, Lovenox HP, Clexane Forte, Hemodialysis Anticoagulation, Eptifibatide

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Deep Vein Thrombosis (DVT), Deep Vein Thrombosis, Deep Vein Thrombosis Prophylaxis after Abdominal Surgery, Deep Vein Thrombosis Prophylaxis after Hip Replacement Surgery, Deep Vein Thrombosis - Prophylaxis, Acute Coronary Syndrome, Deep Vein Thrombosis Prophylaxis after Knee Replacement Surgery, Angina, Myocardial Infarction, Heart Attack

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