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Cidofovir News

Antibodies May Hold Key to HIV Suppression

Posted 10 Nov 2016 by Drugs.com

WEDNESDAY, Nov. 9, 2016 – Antibodies may keep the HIV virus in check and one day let patients stop taking antiretroviral drugs, two new preliminary trials suggest. Researchers tried to quell HIV in 23 patients with infusions of an anti-HIV antibody known as VRC01. The antibody was safe and repressed blood levels of HIV for a short time before the virus reappeared, the researchers said. HIV is the virus that can lead to AIDS. "We were not expecting that we were going to see a prolonged repression, because it was only a single antibody," said co-study author Dr. Anthony Fauci, director of the U.S. National Institute of Allergy and Infectious Diseases. The next phase is to infuse two or three antibodies intermittently, and see if antiretroviral drugs can be withdrawn permanently, he explained. After regular intravenous infusions of VRC01, participants in the U.S. National Institutes of ... Read more

Related support groups: HIV Infection, Valtrex, Acyclovir, Ribavirin, Valacyclovir, Pre-Exposure Prophylaxis, Incivek, Zovirax, Baraclude, Victrelis, Famciclovir, Famvir, Viread, Kaletra, Tenofovir, Ribasphere, Valcyte, Entecavir, Norvir, Copegus

HIV May Hide in Tissues, Even After Treatment

Posted 27 Oct 2016 by Drugs.com

WEDNESDAY, Oct. 26, 2016 – HIV patients who've been treated with antiretroviral drugs still have the AIDS-causing virus in their tissues, a new study suggests. Treatment with antiretrovirals eliminates detectable levels of HIV in the blood and controls the disease. But the new findings suggest that HIV in the tissues may not cause AIDS but could contribute to the development of unrelated conditions, such as cancer and heart disease, according to the University of California, San Francisco (UCSF) researchers. "Looking in tissues of treated HIV patients, we found that HIV in some tissues did not appear to be affected by antiretrovirals," said study senior author Dr. Michael McGrath. "Notably we saw no evidence of drug resistance, which we would have seen if the virus had been exposed to medications," said McGrath. He is UCSF professor of laboratory medicine at the AIDS and Cancer ... Read more

Related support groups: HIV Infection, Valtrex, Acyclovir, Ribavirin, Sovaldi, Valacyclovir, Pre-Exposure Prophylaxis, Incivek, Zovirax, Baraclude, Victrelis, Famciclovir, Famvir, Sofosbuvir, Viread, Kaletra, Tenofovir, Diagnosis and Investigation, Ribasphere, Entecavir

Monkey Study Hints at Drug-Free Suppression of HIV

Posted 13 Oct 2016 by Drugs.com

THURSDAY, Oct. 13, 2016 – Scientists may have found a way to suppress an HIV-like infection in monkeys, without the need for ongoing drug therapy. The researchers added antibody therapy to standard drug treatment given to macaque monkeys infected with simian immunodeficiency virus (SIV). After three months, the animals were taken off the drugs, but their viral levels remained low to undetectable – for close to two years. Experts stressed that the animal findings need to be viewed with caution, and that many questions remain. But, they were also hopeful this could lead to a therapy that frees at least some people from their HIV drug regimens. An initial safety study has already started at the U.S. National Institute of Allergy and Infectious Diseases (NIAID). The drug "cocktails" used to treat HIV – known as combined antiretroviral therapy (ART) – have changed the face of the ... Read more

Related support groups: HIV Infection, Valtrex, Acyclovir, Ribavirin, Valacyclovir, Incivek, Zovirax, Baraclude, Famciclovir, Victrelis, Famvir, Viread, Kaletra, Diagnosis and Investigation, Valcyte, Norvir, Tenofovir, Entecavir, Ribasphere, Copegus

New HIV Treatment Shows Promise in Early Research

Posted 23 Dec 2015 by Drugs.com

WEDNESDAY, Dec. 23, 2015 – Preliminary new research raises the prospect that a recently discovered antibody – an important component of the immune system – could be enlisted to boost the body's response to HIV, the virus that causes AIDS. A single injection of the antibody, currently dubbed VRC01, dramatically reduced the level of HIV in the blood of people who hadn't yet been given antiretroviral drug treatment (ART). ART is the current standard treatment for managing HIV infections, according to the study's authors from the Vaccine Research Center at the National Institute of Allergy and Infectious Diseases in Bethesda, Md. But in people who'd already been treated with ART, the antibody injection had no effect on HIV levels, presumably because the ART therapy had already reduced the levels of HIV virus in their blood, the researchers said. And the researchers were quick to note ... Read more

Related support groups: HIV Infection, Valtrex, Acyclovir, Tamiflu, Ribavirin, Valacyclovir, Pre-Exposure Prophylaxis, Incivek, Zovirax, Baraclude, Famciclovir, Victrelis, Famvir, Viread, Kaletra, Oseltamivir, Valcyte, Norvir, Tenofovir, Ribasphere

FDA Lifts Ban on Blood Donations by Gay Men

Posted 21 Dec 2015 by Drugs.com

MONDAY, Dec. 21, 2015 – Gay and bisexual men who have abstained from sex for one year will now be allowed to donate blood in the United States. The new policy, announced Monday by the U.S. Food and Drug Administration, reverses a three-decades-old ban on donations from this group of men that traces back to the start of the AIDS epidemic. "The FDA's responsibility is to maintain a high level of blood product safety for people whose lives depend on it," FDA Acting Commissioner Stephen Ostroff said in an agency news release. "We have taken great care to ensure this policy revision is backed by sound science and continues to protect our blood supply." The FDA said it was changing its policy based on data from other countries that show allowing such donations would not increase the risk of HIV-tainted blood entering America's blood supply. FDA officials have estimated that about half of the ... Read more

Related support groups: Blood Disorders, Bleeding Disorder, Harvoni, HIV Infection, Valtrex, Anemia, Acyclovir, Tamiflu, Atripla, Ribavirin, Valacyclovir, Pre-Exposure Prophylaxis, Incivek, Blood Transfusion, Zovirax, Truvada, Stribild, Complera, Triumeq, Baraclude

Health Tip: Understanding Antibiotics

Posted 9 Dec 2015 by Drugs.com

-- By taking an antibiotic as prescribed, you can get well faster and help prevent germs from becoming resistant to your medication. The U.S. Centers for Disease Control and Prevention offers these antibiotic guidelines: Never skip a dose of antibiotic. Always take it on schedule, as directed. Never stop taking an antibiotic early. Always take the entire prescription, unless your doctor tells you otherwise. Never save any antibiotic medication for a future illness. Never take an antibiotic that was prescribed for another person. Read more

Related support groups: Infections, Amoxicillin, Metronidazole, Doxycycline, Bacterial Infection, Cephalexin, Clindamycin, Azithromycin, Bactrim, Cipro, Ciprofloxacin, Augmentin, Levaquin, Flagyl, Keflex, Zithromax, Valtrex, Trimethoprim, Sulfamethoxazole, Acyclovir

HIV Therapy May Also Lower Risk for Hepatitis B, Study Says

Posted 12 Oct 2015 by Drugs.com

MONDAY, Oct. 12, 2015 – Not only does effective HIV therapy thwart the AIDS-causing virus, it may also reduce the risk for hepatitis B infection, a new study says. "What this means to us is that effective HIV therapy appears to restore an impairment in the immune response that protects someone with HIV from acquiring hepatitis B infection," study senior author Dr. Chloe Thio, a professor of medicine at Johns Hopkins University School of Medicine, said in a university news release. The study, published in the October issue of Annals of Internal Medicine, involved 2,400 gay and bisexual men who were enrolled in the Multicenter AIDS Cohort Study. Researchers found that the men successfully treated with HIV therapy had the same risk for hepatitis B infection as the men who did not have HIV. Hepatitis B is a virus that can damage the liver. The study showed HIV-positive men on HIV therapy ... Read more

Related support groups: Harvoni, HIV Infection, Valtrex, Acyclovir, Atripla, Hepatitis B, Ribavirin, Sovaldi, Valacyclovir, Pre-Exposure Prophylaxis, Incivek, Zovirax, Truvada, Pegasys, Stribild, Triumeq, Complera, Baraclude, Famciclovir, Victrelis

FDA Medwatch Alert: Vistide (Cidofovir Injection) by Gilead: Recall - Presence Of Particulate Matter

Posted 18 Feb 2013 by Drugs.com

ISSUE: Gilead Sciences, Inc. is voluntarily recalling lot B120217A of Vistide® (cidofovir injection) to the user level due to the presence of  particulate matter found in some vials of this lot. Gilead is not currently aware of any complaint attributable to the particles. BACKGROUND: Vistide is indicated for the treatment of cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome (AIDS).  Vistide is a sterile, hypertonic aqueous solution for intravenous infusion only.  The solution is clear, colorless and supplied in clear glass vials.  It is typically given in a hospital setting or in a doctor’s office. The lot number, B120217A,is located on the product label on the side of the vial. RECOMMENDATION: Gilead has notified its distributors and customers by e-mail and recall letter and is arranging for return of all recalled product. Before injecting Vistide, heal ... Read more

Related support groups: Cidofovir, Vistide, CMV Retinitis

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Smallpox Vaccine Reaction, CMV Retinitis

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Vistide

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