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Chronic Kidney Disease News

Related terms: CKD, Chronic Renal Disease, CRD

Dialysis Patients May Walk Their Way to Better Health

Posted 3 days ago by Drugs.com

THURSDAY, Dec. 1, 2016 – Improved mental and physical health may just be steps away for people on kidney dialysis, a new study suggests. A simple program that includes a few minutes of walking a day appears to benefit these patients, a team of Italian researchers concluded. One kidney disease expert in the United States applauded the new research. "It is encouraging to see that our minds and bodies can still be adaptable to physical effort," even when dialysis is needed, said Dr. Maria DeVita, associate chief of nephrology at Lenox Hill Hospital in New York City. "This program should be immediately implemented in all our patients," she added. "What's there to lose? Just do it!" According to the study authors, prior research has shown that exercise has a positive impact on dialysis patients. In the new study, researchers led by Dr. Carmine Zoccali wanted to see if that was true for even ... Read more

Related support groups: Renal Failure, Chronic Kidney Disease, Peritoneal dialysis, Hyperphosphatemia of Renal Failure

Kidney Cancer Drug Shows Promise in Early Trial

Posted 4 days ago by Drugs.com

WEDNESDAY, Nov. 30, 2016 – An experimental drug may show promise in treating kidney cancer, researchers say. The drug CB-839 is the first to target an enzyme that cancer cells require to stay alive, researchers said. This stage 1 clinical trial found that the drug was effective in most patients with advanced kidney cancer when used in combination with another cancer drug called everolimus (Afinitor, Zortress). In the 15 patients in the study, the dual treatment controlled tumors in 93 percent of the patients, who had either clear cell or papillary renal cell cancer. Tumors shrank by more than 30 percent in one patient, were stable in 13 patients, and grew by more than 20 percent in one patient. Clear cell is the most common form of kidney cancer, accounting for 75 percent of cases, the researchers said. All 12 patients with this type of kidney cancer had their disease controlled. ... Read more

Related support groups: Renal Failure, Renal Cell Carcinoma, Chronic Kidney Disease, Afinitor, Peritoneal dialysis, Renal Osteodystrophy, Everolimus, Wilms' Tumor, Zortress, Hyperphosphatemia of Renal Failure, Afinitor Disperz

Poor Sleep Linked to Worsening Kidney Disease

Posted 14 days ago by Drugs.com

SATURDAY, Nov. 19, 2016 – For people with chronic kidney disease, poor sleep may boost the chances that their illness will worsen, new research suggests. "Short sleep and fragmented sleep are significant yet unappreciated risk factors for chronic kidney disease progression," said study author Dr. Ana Ricardo, of the University of Illinois at Chicago. "Our research adds to the accumulating knowledge regarding the importance of sleep on kidney function, and underscores the need to design and test clinical interventions to improve sleep habits in individuals with chronic kidney disease," she said in a news release from the American Society of Nephrology. However, it's not clear from the study that a lack of sleep is what caused the worsening kidney failure. The study was only able to find an association between these factors. The research included 432 adults with chronic kidney disease. ... Read more

Related support groups: Sleep Disorders, Insomnia, Fatigue, Renal Failure, Sleep Apnea, Chronic Kidney Disease, Hyperphosphatemia of Renal Failure

Smoking May Hinder Kidney Disease Drugs

Posted 16 days ago by Drugs.com

FRIDAY, Nov. 18, 2016 – Cigarette smoking may decrease the effectiveness of drugs taken during early stages of chronic kidney disease, a small study suggests. Blood pressure-lowering drugs known as angiotensin-converting enzyme inhibitors slow kidney decline by relaxing blood vessels. "It has practically become dogma that if you have a patient with high blood pressure and chronic kidney disease that you start them on an angiotensin-converting enzyme inhibitor," said study author Dr. Bethany Roehm, of Tufts Medical Center in Boston. "We are often comforted as clinicians that we are doing something to help slow progression of their kidney disease in doing this," Roehm added in a news release from the American Society of Nephrology. "But our data suggest that this may not be the case for smokers, and our study underscores the importance of doing all we can as clinicians to encourage our ... Read more

Related support groups: Lisinopril, Smoking, Smoking Cessation, Renal Failure, Ramipril, Enalapril, Benazepril, Chronic Kidney Disease, Perindopril, Quinapril, Zestril, Vasotec, Altace, Lotensin, Captopril, Accupril, Prinivil, Fosinopril, Monopril, Capoten

Can Time-Release Capsules Replace Daily Pills?

Posted 18 days ago by Drugs.com

WEDNESDAY, Nov. 16, 2016 – A new type of drug capsule might one day replace the need to take medicines every day, but so far it has only been tested in pigs, researchers report. A capsule that contains a six-armed star containing drugs can remain in the stomach and release its medication over time. That means instead of taking daily medication, patients would only have to swallow one capsule weekly or monthly, the researchers said. "We have the potential for an ultra-long capsule for medications that folks are currently taking once or twice or three times a day – that can now be given once a week or once a month," said researcher Dr. Giovanni Traverso. He is an instructor in the division of gastroenterology at Brigham and Women's Hospital in Boston. "This can make life a lot easier, because patients are more likely to take a medication when it's dosed once a week versus once a day," ... Read more

Related support groups: Schizophrenia, HIV Infection, Schizoaffective Disorder, Renal Failure, Alzheimer's Disease, Pre-Exposure Prophylaxis, Chronic Kidney Disease, Hyperphosphatemia of Renal Failure

Constipation, Kidney Disease May Be Linked, New Research Shows

Posted 11 Nov 2016 by Drugs.com

THURSDAY, Nov. 10, 2016 – People with constipation are more likely to develop kidney disease, a new study finds. The discovery suggests kidney problems might be prevented or treated by managing constipation, according to researchers at the University of Tennessee Health Science Center and Memphis VA Medical Center. They studied the medical records of 3.5 million U.S. veterans with normal kidney function. They were tracked from 2004 to 2006, and followed through 2013. Those with constipation were 13 percent more likely than patients without constipation to develop chronic kidney disease and 9 percent more likely to experience kidney failure. The risk was even higher for those whose constipation was more severe. The study did not prove that constipation causes kidney disease or failure, however. Instead, "Our findings highlight the plausible link between the gut and the kidneys and ... Read more

Related support groups: Constipation, Renal Failure, Constipation - Chronic, Chronic Kidney Disease, Constipation - Acute, Constipation - Drug Induced, Renal and Genitourinary Disorders, Fecal Impaction

Concern About Dialysis Safety Spurs CDC Action

Posted 29 Sep 2016 by Drugs.com

THURSDAY, Sept. 29, 2016 – Steps to reduce bloodstream infections in dialysis patients will be mapped out Thursday at a meeting of the U.S. Centers for Disease Control and Prevention and a coalition of kidney and dialysis groups. Dialysis treatment – either in a hospital, a dialysis unit or at home – is needed when the kidneys cannot filter wastes from the body sufficiently. Each year, about 37,000 dialysis patients in the United States develop potentially deadly bloodstream infections associated with their treatment, the CDC says. That number could be cut in half if dialysis facilities implemented CDC guidelines for dialysis safety, according to the agency. "Making evidence-based safety steps a routine part of patient care is a proven strategy to keep dialysis patients safe from bloodstream infections," CDC Director Dr. Tom Frieden said in an agency news release. "We appreciate the ... Read more

Related support groups: Infections, Renal Failure, Chronic Kidney Disease, Hemodialysis, Peritoneal dialysis

Kidney Stone? Try a Roller Coaster Ride

Posted 27 Sep 2016 by Drugs.com

TUESDAY, Sept. 27, 2016 – Anyone who's suffered a kidney stone just wants the urinary obstruction gone. Now, preliminary research suggests relief might even be fun: a roller coaster ride. There's been anecdotal evidence from patients that these amusement park rides can help pass a small stone, explained Dr. David Wartinger, a professor of urology at the Michigan State University College of Osteopathic Medicine, in East Lansing. His team's new research – conducted on the Big Thunder Mountain Railroad and Space Mountain roller coasters at Orlando's Walt Disney World – seems to support that view. In the study, Wartinger's group used 3D printing to create a clear silicone model of a kidney that contained urine, plus three different-sized kidney stones. They placed the kidney model in a backpack and took it on 60 roller coaster rides. "A ride on a moderate-intensity roller coaster could ... Read more

Related support groups: Renal Failure, Chronic Kidney Disease, Renal Osteodystrophy, Hypercalciuria, Calcium Oxalate Calculi with Hyperuricosuria

Fruits, Veggies Powerful Rx for Kidney Disease: Study

Posted 14 Sep 2016 by Drugs.com

WEDNESDAY, Sept. 14, 2016 – Kidney disease patients who eat three to four more servings of fruits and vegetables every day could lower their blood pressure and nearly halve their medication costs, new research suggests. The findings stem from the multi-year tracking of a small group of patients, in which standard medical treatment was compared with the simple nutritional intervention. The goal: to see which approach did a better job at driving down both blood pressure and drug expenses. The result on both fronts showed a clear win for healthy food. Study author Dr. Nimrit Goraya described the links seen between increased fruit and vegetable intake, kidney disease control and lower medication expenses as "huge." And "the impact was visible from the very first year," she said. "This study has been done over five years, but every year since the therapy with fruits and vegetables began, we ... Read more

Related support groups: High Blood Pressure, Hypertension, Renal Failure, Chronic Kidney Disease, Hypertensive Heart Disease

Do Overweight People Fare Better Than Others With Kidney Cancer?

Posted 7 Sep 2016 by Drugs.com

WEDNESDAY, Sept. 7, 2016 – Obesity is a risk factor for kidney cancer. Yet, obese people with advanced kidney cancer seem to live longer than normal-weight or underweight patients, a new study finds. In one database of nearly 2,000 patients with advanced kidney cancer, those who were obese or overweight survived nearly 26 months, compared to 17 months for those of normal weight. And, overweight patients were 16 percent less likely to die during the study period, the researchers reported. Similar findings were uncovered using three other databases. The records of more than 7,000 kidney cancer patients were reviewed by the study authors. "Paradoxically, when overweight individuals developed kidney cancer, especially in its advanced, metastatic form, their disease progressed more slowly and they lived longer than their normal-weight counterparts," said lead researcher Dr. Toni Choueiri. ... Read more

Related support groups: Obesity, Cancer, Renal Failure, Renal Cell Carcinoma, Chronic Kidney Disease, Urinary Tract Tumors, Wilms' Tumor, Urinary Tract Cancer

Heart Rhythm Disorder May Be Tied to Wider Range of Ills

Posted 7 Sep 2016 by Drugs.com

WEDNESDAY, Sept. 7, 2016 – Atrial fibrillation, a common type of heart rhythm disorder, is associated with a wider range of conditions than previously believed, researchers report. The findings add "to the growing literature on the association between atrial fibrillation and cardiovascular outcomes beyond stroke," researchers at the University of Oxford in England and the Massachusetts Institute of Technology wrote. The team reviewed 104 studies involving more than 9 million people, including nearly 590,000 people with atrial fibrillation. They concluded that the heart rhythm disorder was also associated with heart disease, heart failure, kidney disease, sudden cardiac death and death from all causes. The study did not prove atrial fibrillation caused these additional health risks, just that there was an association. Risk for heart failure was the most significant of these ... Read more

Related support groups: Heart Disease, Atrial Fibrillation, Heart Attack, Renal Failure, Transient Ischemic Attack, Prevention of Thromboembolism in Atrial Fibrillation, Myocardial Infarction, Chronic Kidney Disease, Ischemic Stroke - Prophylaxis, Thromboembolic Stroke Prophylaxis

Diet Supplement May Help Prevent Kidney Stones: Study

Posted 8 Aug 2016 by Drugs.com

MONDAY, Aug. 8, 2016 – A dietary supplement may hold the power to dissolve a key component of kidney stones, potentially offering a new prevention tool against this painful condition, researchers say. It's too early to be sure if the compound hydroxycitrate will become a preventive treatment for kidney stones, since extensive research in people hasn't begun. Still, it could offer an alternative to potassium citrate, which treats kidney stones but has side effects, the study authors explained. At issue: the calcium oxalate crystals that are the most common component of kidney stones, mineral deposits that form inside the kidneys. They may get stuck in the urinary tract, blocking urination and causing great pain. Kidney stones affect an estimated 12 percent of men and 7 percent of women. High blood pressure, diabetes and obesity can increase the risk. Physicians often urge people who are ... Read more

Related support groups: Dietary Supplementation, Chronic Kidney Disease, Urinary Tract Stones, Calcium Oxalate Calculi with Hyperuricosuria, Renal and Genitourinary Disorders

Some Advanced Kidney Cancer Patients May Postpone Treatment

Posted 4 Aug 2016 by Drugs.com

THURSDAY, Aug. 4, 2016 – Not all adults with advanced kidney cancer that has spread require immediate, aggressive treatment, a small new study suggests. "A subset of adults with advanced kidney cancer have slow-growing disease that can be safely managed using active surveillance," explained study lead author Brian Rini, of the Cleveland Clinic's Taussig Cancer Institute. This "watch and wait" approach, instead of active treatment, "could spare them the inconvenience and debilitating side effects of aggressive treatments for about a year, and in some cases several years, without worsening anxiety and depression," Rini said in a news release from The Lancet Oncology. The journal published the findings Aug. 4. In advanced kidney cancer, drugs such as sunitinib and sorafenib are typically used. While they can slow disease progression, they do not cure it, the researchers said. Could some ... Read more

Related support groups: Cancer, Renal Failure, Chronic Kidney Disease, Sutent, Nexavar, Sunitinib, Sorafenib, Wilms' Tumor, Urinary Tract Cancer

Too Much Red Meat Might Harm Kidneys, Study Suggests

Posted 14 Jul 2016 by Drugs.com

THURSDAY, July 14, 2016 – Eating red meat may boost the risk for kidney failure, but swapping even one daily serving of red meat for another protein may reduce the risk, a large study from Singapore suggests. Red meat intake – in this case, mostly pork – was strongly associated with an increased risk of end-stage renal disease, the loss of normal kidney function. The relationship was also "dose dependent" – meaning the higher the consumption, the greater the risk. The association held up even after compensating for factors that could skew the results, such as lifestyle and other health conditions, the study authors noted. "Our findings suggest that patients with chronic kidney disease or the general population worried about their kidney health can still maintain protein intake but consider switching to plant-based sources," said Dr. Woon-Puay Koh, professor in the Office of Clinical ... Read more

Related support groups: Renal Failure, Chronic Kidney Disease, Renal and Genitourinary Disorders, Anuria

3-D Printed Model Helps Delicate Kidney Surgery

Posted 9 Jul 2016 by Drugs.com

FRIDAY, July 8, 2016 – Cutting-edge 3-D technology is making more inroads in medicine, this time helping doctors save a patient's kidney during difficult tumor-removal surgery. Patient Linda Green's tumor was located in a challenging location next to vital arteries and veins, explained doctors at Intermountain Medical Center in Salt Lake City. To prepare for the surgery, CT scans were used to produce an exact 3D-printed model of the patient's kidney. The model had two halves, which enabled the doctors to determine exactly how the tumor was attached to the patient's kidney. Based on this information, the patient's surgical team was able to work around the sensitive areas, successfully remove the tumor, and save the kidney. The model helped them spot a small "nub" of the tumor that had grown up into a pocket of the kidney. "Without the 3D model, the visual images of the CT scans would ... Read more

Related support groups: Renal Failure, Renal Transplant, Chronic Kidney Disease, Peritoneal dialysis, Organ Transplant, Kidney Transplant, Hyperphosphatemia of Renal Failure

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