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Celebrex May Not Pose Bigger Heart Risk Than Similar Drugs: Study

Posted 14 Nov 2016 by Drugs.com

MONDAY, Nov. 14, 2016 – Some people taking the pain reliever Celebrex may not have a greater risk for heart problems than those taking other nonsteroidal anti-inflammatory drugs (NSAIDs), a new study says. Celebrex (celecoxib) is a COX-2 inhibitor. That's the same class of drugs as Vioxx and Bextra, which were pulled from the market in 2004 and 2005, respectively, because they were linked to heart problems. Celebrex didn't seem to share the same issues, so has remained available. And the new trial's "primary message is that celecoxib is not riskier for the heart than other NSAIDs," said study director Dr. Steven Nissen in a Cleveland Clinic news release. Nissen is chair of the Department of Cardiovascular Medicine. Nissen's prior research was instrumental in uncovering the cardiovascular risks associated with COX-2 inhibitors. The new study seems to reaffirm Celebrex's safety profile. ... Read more

Related support groups: Ibuprofen, Naproxen, Heart Disease, Celebrex, Advil, Aleve, Motrin, Vicoprofen, Naprosyn, Prevention of Cardiovascular Disease, Advil PM, Treximet, Vimovo, Advil Cold and Sinus, Vioxx, Celecoxib, Naprelan '375', Cardiovascular Risk Reduction, Naprelan, Hydrocodone/Ibuprofen

Giving the 'Green Light' to Migraine Relief

Posted 17 May 2016 by Drugs.com

TUESDAY, May 17, 2016 – A new study sheds light – literally – on a potential means of easing migraine pain. Researchers in Boston exposed 69 migraine patients to different colors of light. They found that while blue light exacerbated headache pain, a narrow spectrum of low-intensity green light significantly reduced light sensitivity. In some cases, this green light also reduced migraine pain by about 20 percent, the researchers found. They noted that migraine headache affects nearly 15 percent of people worldwide, and a frequent symptom of migraine is light sensitivity, also known as photophobia. "Although photophobia is not usually as incapacitating as headache pain itself, the inability to endure light can be disabling," study author Rami Burstein, of Beth Israel Deaconess Medical Center in Boston, said in a medical center news release. "More than 80 percent of migraine attacks ... Read more

Related support groups: Migraine, Celebrex, Fioricet, Excedrin, Imitrex, Tylenol PM, Sumatriptan, Maxalt, Fiorinal, Seasonal Affective Disorder, Excedrin Migraine, Cafergot, Zomig, Relpax, Advil PM, Treximet, Midrin, Esgic, Vioxx, Ergotamine

X-Rays May Miss Hip Arthritis, Study Finds

Posted 10 Dec 2015 by Drugs.com

THURSDAY, Dec. 10, 2015 – X-rays don't detect hip arthritis in many patients, resulting in delayed diagnosis and treatment, researchers report. The researchers looked at information from almost 4,500 Americans taking part in two arthritis studies. In one study, only 16 percent of patients with hip pain had X-ray evidence of osteoarthritis in the hip and only 21 percent of those with X-ray evidence of arthritis had hip pain. In the other study, the rates were 9 percent and 24 percent, respectively, according to the findings reported recently in the journal BMJ. "The majority of older subjects with high suspicion for clinical hip osteoarthritis did not have radiographic hip osteoarthritis, suggesting that many older persons with hip osteoarthritis might be missed if diagnosticians relied on hip radiographs to determine if hip pain was due to osteoarthritis," said study corresponding ... Read more

Related support groups: Pain, Suboxone, Oxycodone, Hydrocodone, Methadone, Percocet, Tramadol, OxyContin, Vicodin, Norco, Fentanyl, Morphine, Osteoarthritis, Codeine, Lortab, Tylenol, Chronic Pain, Opana, Ibuprofen, Subutex

Experts Urge Caution With Popular Painkillers After FDA Warning

Posted 10 Jul 2015 by Drugs.com

FRIDAY, July 10, 2015 – People who regularly reach for widely used painkillers like ibuprofen and naproxen may need to think carefully before they pop those pills, heart experts say. Mounting evidence has shown that chronic use of non-steroidal anti-inflammatory drugs (NSAIDs) can raise a person's risk of heart attack and stroke. The evidence is strong enough that the U.S. Food and Drug Administration on Thursday ordered drug makers to toughen warning labels on both prescription and over-the-counter NSAIDs. The tougher warning does not include aspirin, an NSAID that has been shown to lower heart risks in some patients. Most people who occasionally take ibuprofen (Advil, Motrin) or naproxen (Aleve) for infrequent headaches or pain don't have to worry, as long as they follow the dosage directions on the bottle, said Dr. Richard Chazal, president-elect of the American College of ... Read more

Related support groups: Pain, Ibuprofen, Naproxen, Meloxicam, Celebrex, Advil, Diclofenac, Voltaren, Aleve, Mobic, Voltaren Gel, Motrin, Indomethacin, Toradol, Etodolac, Vicoprofen, Nabumetone, Flector, Flector Patch, Ketorolac

FDA Strengthens Heart Attack, Stroke Warning for Popular Painkillers

Posted 10 Jul 2015 by Drugs.com

THURSDAY, July 9, 2015 – The U.S Food and Drug Administration on Thursday strengthened the warning labels for widely used painkillers like ibuprofen and naproxen, saying they can increase the risk of heart attack or stroke. The FDA is asking people to think carefully about their use of nonsteroidal anti-inflammatory drugs (NSAIDs), particularly if they've already had a heart attack, according to a consumer update on the agency's website. The agency said it is taking this action based on recent data that shows the risk of heart attack or stroke can increase even after using NSAIDs for a short time. "They used to say they might cause risk of heart attack or stroke. Now we are saying they do cause increased risk of heart attack and stroke," FDA spokesman Eric Pahon told NBC News. In particular, people should avoid taking multiple products that contain NSAIDs, according to the revised FDA ... Read more

Related support groups: Ibuprofen, Naproxen, Meloxicam, Celebrex, Advil, Diclofenac, Voltaren, Aleve, Mobic, Voltaren Gel, Motrin, Indomethacin, Toradol, Etodolac, Vicoprofen, Nabumetone, Flector, Flector Patch, Ketorolac, Arthrotec

FDA Medwatch Alert: Non-aspirin Nonsteroidal Anti-inflammatory Drugs (NSAIDs): Drug Safety Communication - FDA Strengthens Warning of Increased Chance of Heart Attack or Stroke

Posted 10 Jul 2015 by Drugs.com

[Posted 07/09/2015] ISSUE:  FDA is strengthening an existing label warning that non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) increase the chance of a heart attack or stroke. Based on FDAs comprehensive review of new safety information, FDA is requiring updates to the drug labels of all prescription NSAIDs. As is the case with current prescription NSAID labels, the Drug Facts labels of over-the-counter (OTC) non-aspirin NSAIDs already contain information on heart attack and stroke risk. FDA will also request updates to the OTC non-aspirin NSAID Drug Facts labels. See the FDA Drug Safety Communication (Table 1) for a list of non-aspirin nonsteroidal anti-inflammatory drug products. Prescription NSAID labels will be revised to reflect the following information: The risk of heart attack or stroke can occur as early as the first weeks of using an NSAID. The risk may increase ... Read more

Related support groups: Ibuprofen, Naproxen, Meloxicam, Celebrex, Advil, Diclofenac, Voltaren, Aleve, Mobic, Voltaren Gel, Motrin, Indomethacin, Toradol, Etodolac, Vicoprofen, Nabumetone, Flector, Flector Patch, Ketorolac, Arthrotec

Certain Painkillers Ill-Advised After Heart Attack: Study

Posted 24 Feb 2015 by Drugs.com

TUESDAY, Feb. 24, 2015 – Common painkillers such as ibuprofen and Celebrex may raise the risk for heart attack, stroke and/or serious bleeding among heart attack survivors taking prescription blood thinners, a new study says. The finding could prompt widespread concern, given that these painkillers – known as nonsteroidal anti-inflammatory drugs (NSAIDs) – and anti-clot medications are widely used by heart attack survivors, researchers said. "For all sorts of reasons, many of us have been concerned about NSAIDs in a heart attack context for a long time," said Dr. Charles Campbell, chief of cardiovascular medicine at the University of Tennessee Erlanger Health Systems in Chattanooga. "For example, we know NSAIDs have an adverse effect on the kidney. And we have long worried that what this study has found was going to be the case." There appeared to be no safe window period for taking ... Read more

Related support groups: Ibuprofen, Naproxen, Heart Disease, Heart Attack, Celebrex, Diclofenac, Advil, Voltaren, Aleve, Motrin, Myocardial Infarction, Flector, Naprosyn, Celecoxib, Cataflam, Naprelan '375', Naprelan, Zipsor, Anaprox, Cambia

Some Painkillers Tied to Bleeding Risk in Those With Abnormal Heartbeat

Posted 17 Nov 2014 by Drugs.com

MONDAY, Nov. 17, 2014 – People with the abnormal heartbeat known as atrial fibrillation who take common painkillers might significantly increase their risk for bleeding and blood clots, according to a new study. That risk was even higher among patients who took a blood thinner along with one of these nonsteroidal anti-inflammatory painkiller drugs (NSAIDs), which include aspirin, ibuprofen (Motrin), naproxen (Aleve) and celecoxib (Celebrex). "If you add NSAIDs on top of blood-thinning medication, you double the risk of bleeding," said lead researcher Dr. Gunnar Gislason, from the Danish Heart Foundation in Copenhagen. Many people with atrial fibrillation take blood thinners to reduce the risk of stroke, he noted. Atrial fibrillation causes the upper chambers of the heart to contract quickly and irregularly. These abnormal contractions allow blood to pool in the heart, forming clots ... Read more

Related support groups: Aspirin, Ibuprofen, Naproxen, Atrial Fibrillation, Meloxicam, Celebrex, Advil, Diclofenac, Voltaren, Aleve, Mobic, Motrin, Indomethacin, Toradol, Etodolac, Nabumetone, Flector, Ketorolac, Arthrotec, Naprosyn

Certain Painkillers Tied to Raised Risk of Death After Stroke

Posted 5 Nov 2014 by Drugs.com

WEDNESDAY, Nov. 5, 2014 – Arthritis pain relievers known as COX-2 inhibitors, including Celebrex and Lodine, are associated with an increased risk of dying within a month after a stroke, according to a new study. "This large study from Denmark adds to the prior concerns about COX-2 inhibitors and stroke risks," said Dr. Ralph Sacco, chairman of neurology at the University of Miami Miller School of Medicine. "Patients at high risk for stroke should be cautious about taking such medications and should consult their physicians as to the best medications to treat inflammation and pain," Sacco said. However, while the study found an association between use of these painkillers and death in stroke patients, it did not prove cause-and-effect. Other types of nonsteroidal anti-inflammatory painkillers (NSAIDs) – including ibuprofen (Advil, Motrin) and naproxen (Aleve) – weren't linked to an ... Read more

Related support groups: Celebrex, Etodolac, Lodine, Vioxx, Celecoxib, Lodine XL, Valdecoxib, Bextra, Rofecoxib

FDA Approves Generic Version of Painkiller Celebrex

Posted 30 May 2014 by Drugs.com

FRIDAY, May 30, 2014 – The U.S. Food and Drug Administration on Friday gave its approval to the first generic version of the powerful pain reliever Celebrex (celecoxib). Celecoxib is a member of the cox-2 inhibitor family of painkillers, prescription medicines often used for arthritis and other conditions. The drugs emerged in the early 2000s and included once best-selling pain relievers such as Vioxx and Bextra. However, Vioxx was pulled from the market in 2004 after studies revealed use of the drug raised heart risks, and the withdrawal of Bextra followed a year later. Celebrex has remained the only cox-2 inhibitor medication on drugstore shelves in the years since. On Friday, Teva Pharmaceutical Industries got the nod from the FDA to market cheaper generic versions of celecoxib capsules in 50 milligram, 100 mg, 200 mg, and 400 mg strengths. Mylan Pharmaceuticals Inc. received ... Read more

Related support groups: Celebrex, Celecoxib

FDA Takes Action to Protect Consumers from Dangerous Medicines Sold by Illegal Online Pharmacies

Posted 27 Jun 2013 by Drugs.com

June 27, 2013 – The U.S. Food and Drug Administration, in partnership with international regulatory and law enforcement agencies, took action this week against more than 9,600 websites that illegally sell potentially dangerous, unapproved prescription medicines to consumers. These actions include the issuance of regulatory warnings, and seizure of offending websites and $41,104,386 worth of illegal medicines worldwide. The action occurred as part of the 6th annual International Internet Week of Action (IIWA), a global cooperative effort to combat the online sale and distribution of potentially counterfeit and illegal medical products. As part of this year’s international effort – Operation Pangea VI – the FDA’s Office of Criminal Investigations, in coordination with the United States Attorney's Office for the District of Colorado, seized and shut down 1,677 illegal pharmacy websites. ... Read more

Related support groups: Viagra, Celebrex, Levitra, Sildenafil, Clozapine, Clozaril, Staxyn, Revatio, Celecoxib, Vardenafil, Clopine, Glimepiride/Rosiglitazone, FazaClo, Versacloz, Zaponex, Clozapine Synthon, Denzapine, Avandaryl

Common Painkillers Might Boost Odds for Second Heart Attack

Posted 11 Sep 2012 by Drugs.com

MONDAY, Sept. 10 – People who've already suffered a heart attack may face higher odds of death or subsequent heart attack if they regularly take a common form of painkiller, Danish researchers report. The painkillers are known as nonsteroidal anti-inflammatory drugs (NSAIDs), and include over-the-counter drugs such as ibuprofen (Advil, Motrin) and naproxen (Aleve), as well as prescription drugs such as Celebrex (celecoxib), the researchers noted. "These results support previous findings that NSAIDs have no apparent safe treatment window among patients with a [prior] heart attack," said lead researcher Dr. Anne-Marie Schjerning Olsen from the department of cardiology at the University of Copenhagen. "Long-term caution with use of NSAIDs is advised in all patients after a heart attack," she said. Olsen added that "it is important to get the message out to clinicians taking care of ... Read more

Related support groups: Ibuprofen, Naproxen, Heart Attack, Meloxicam, Celebrex, Advil, Diclofenac, Voltaren, Aleve, Mobic, Motrin, Indomethacin, Toradol, Etodolac, Myocardial Infarction, Nabumetone, Flector, Ketorolac, Arthrotec, Naprosyn

Common Painkillers May Help Prevent Skin Cancer: Study

Posted 29 May 2012 by Drugs.com

TUESDAY, May 29 – Taking nonsteroidal anti-inflammatory drugs (NSAIDs) – which include medicine cabinet staples such as aspirin, Motrin and Aleve – appears to significantly lower the risk for developing several major forms of skin cancer, a new Danish study reveals. What's more, the apparent protective impact of both prescription and nonprescription NSAIDs on skin cancer risk seems to be stronger the longer someone takes them. Over-the-counter NSAIDs are used to control pain, fever and swelling. NSAIDs also include prescription medicines called COX-2 enzyme inhibitors, such as Celebrex (celecoxib). "Our study showed that users of common painkillers, known as NSAIDs, have a lower risk of the three major types of skin cancer, [including] malignant melanoma, basal cell carcinoma and squamous cell carcinoma," said study lead author, Sigrun Alba Johannesdottir, at the department of ... Read more

Related support groups: Aspirin, Ibuprofen, Naproxen, Meloxicam, Celebrex, Diclofenac, Advil, Voltaren, Aleve, Mobic, Motrin, Indomethacin, Basal Cell Carcinoma, Toradol, Etodolac, Nabumetone, Skin Cancer, Flector, Ketorolac, Arthrotec

Scientists Spot How Cox-2 Painkillers Raise Heart Risks

Posted 2 May 2012 by Drugs.com

WEDNESDAY, May 2 – New research has uncovered how some cox-2 painkillers increase the risk for both heart attacks and stroke. The once popular cox-2 drugs, Vioxx and Bextra, were pulled off the market in 2004 and 2005, respectively, after research showed that both raised the chances of cardiovascular trouble. Meanwhile, Celebrex, a painkiller in the same drug class that remains on the market, carries a "black box" warning alerting patients to potential heart risks. Now, a team of scientists from the University of Pennsylvania in Philadelphia say that, although cox-2 inhibitors are very good at inhibiting the workings of the cox-2 enzyme – and thereby easing pain – they also throw off the cardiovascular system's delicate balance by inhibiting an enzyme that relaxes blood vessels and guards against clotting. "It's really about a rock and a hard place," said Dr. Christopher Cannon, a ... Read more

Related support groups: Celebrex, Vioxx, Celecoxib, Valdecoxib, Bextra, Rofecoxib

Some Pain Meds Riskier for Cardiac Patients Than Others, Study Suggests

Posted 28 Sep 2011 by Drugs.com

From Canadian Press DataFile (September 27, 2011) By Helen Branswell TORONTO – A new study suggests some commonly consumed pain medications are riskier than others when used by people with cardiovascular problems. The research suggests a couple of the drugs carry the same level of risk as Vioxx, which was taken off the market in 2004 over heart health concerns. Senior author Dr. David Henry says the increased risk from this class of drugs is not significant for the average healthy individual taking the drugs occasionally. But he says the risk profile changes in people who have already had a heart attack or who are at risk of cardiovascular events because they have diabetes, high blood pressure or a family history of heart disease. "So we're really worried about people who might have an annual risk of maybe five per cent," said Henry, who is CEO of the Toronto-based Institute for ... Read more

Related support groups: Aspirin, Ibuprofen, Naproxen, Meloxicam, Celebrex, Advil, Diclofenac, Voltaren, Aleve, Mobic, Motrin, Indomethacin, Toradol, Etodolac, Nabumetone, Flector, Ketorolac, Arthrotec, Naprosyn, Lodine

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