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Calcium May Cut Risk for Precancerous Colon Lesions in Some People

Posted 10 Apr 2013 by Drugs.com

WEDNESDAY, April 10 – Consuming higher amounts of calcium may lower the likelihood of precancerous colon and rectal lesions in people who are at increased risk due to variations in two genes, a new study suggests. High calcium intake did not affect risk in people without the genetic variations. The findings may help explain inconsistent results in previous research about the link between calcium intake and the risk for these lesions, called colorectal adenomas, the researchers said. They also said the findings may help identify patients who would benefit from calcium supplements or higher levels of calcium in their diet. The study of nearly 6,000 people in Tennessee found that patients with the highest calcium intake had no reduced risk for colorectal adenomas if they had no variations in two genes – KCNJ1 and SLC12A1 – that are essential in calcium reabsorption in the kidneys. ... Read more

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