Skip to Content

Join the 'Caduet' group to help and get support from people like you.

Caduet News

Drug Combo for Irregular Heartbeat Might Raise Bleeding Risk

Posted 14 days ago by Drugs.com

MONDAY, Nov. 21, 2016 – Because the irregular heartbeat known as atrial fibrillation can trigger stroke-inducing clots, many patients are prescribed a blood thinner. But a new Canadian study suggests that combining one blood thinner, Pradaxa, with certain statin medications could raise the odds for bleeding in these patients. "An increase in the risk of bleeding requiring hospital admission or emergency department visits was seen with lovastatin [Mevacor] and simvastatin [Zocor] compared with the other statins," said study author Tony Antoniou, a pharmacist at St. Michael's Hospital in Toronto. His team tracked outcomes for nearly 46,000 patients ages 65 and older. All had atrial fibrillation and took Pradaxa (dabigatran) to reduce their risk of stroke. Those who also took either lovastatin or simvastatin had a 40 percent higher risk of bleeding than those who took other statins, the ... Read more

Related support groups: Bleeding Disorder, Atrial Fibrillation, Lipitor, Simvastatin, Crestor, Atorvastatin, Pravastatin, Pradaxa, Zocor, Lovastatin, Prevention of Thromboembolism in Atrial Fibrillation, Vytorin, Rosuvastatin, Pravachol, Livalo, Red Yeast Rice, Caduet, Simcor, Lescol, Mevacor

Bonus From Your Blood Pressure Med: Fewer Fractures?

Posted 14 days ago by Drugs.com

MONDAY, Nov. 21, 2016 – High blood pressure and weakened bones are two big health issues for seniors. Now, new data suggests that one class of drugs might help protect against both. The study of thousands of Veterans Affairs (VA) and Medicare patients found that anti-hypertension meds called thiazide diuretics also seemed to lower odds of a patient suffering a hip or pelvic fracture, compared with people on other high blood pressure medications. The finding made sense to one endocrinologist. "It is well known that thiazide therapy can lower calcium excretion into the urine by as much as 50 percent," said Dr. Caroline Messer, who reviewed the new findings. "This tendency towards a positive calcium balance in the body may [slow] bone loss and reduce fracture risk," explained Messer. She directs the Center for Pituitary and Neuroendocrine Disorders at Lenox Hill Hospital in New York City. ... Read more

Related support groups: High Blood Pressure, Lisinopril, Hypertension, Amlodipine, Norvasc, Azor, Exforge, Fracture, bone, Lotrel, Hydrochlorothiazide/Lisinopril, Zestril, Tribenzor, Caduet, Amlodipine/Benazepril, Hyponatremia, Zestoretic, Twynsta, Prinivil, Exforge HCT, Compression Fracture of Vertebral Column

High Blood Pressure Rates Have Doubled Worldwide Since 1975

Posted 19 days ago by Drugs.com

WEDNESDAY, Nov. 16, 2016 – The number of people worldwide with high blood pressure has nearly doubled over the past 40 years, a new study reveals. At the same time, average blood pressure levels are at an all-time low in the United States and other developed nations, the researchers said. "High blood pressure is the leading risk factor for stroke and heart disease, and kills around 7.5 million people worldwide every year. Most of these deaths are experienced in the developing world," said study author Majid Ezzati, a professor at Imperial College, London in England. "Taken globally, high blood pressure is no longer a problem of the Western world or wealthy countries. It is a problem of the world's poorest countries and people," Ezzati added. The overall number of people with high blood pressure ("hypertension") rose from 594 million in 1975 to more than 1 billion in 2015, due to ... Read more

Related support groups: Obesity, High Blood Pressure, Hypertension, Azor, Exforge, Benicar HCT, Diovan HCT, Hyzaar, Lotrel, Avalide, Hydrochlorothiazide/Lisinopril, Micardis HCT, Tribenzor, Caduet, Ziac, Tarka, Edarbyclor, Amlodipine/Benazepril, Zestoretic, Twynsta

Coming Soon: Lower Cholesterol From a Twice-a-Year Shot?

Posted 20 days ago by Drugs.com

TUESDAY, Nov. 15, 2016 – Instead of popping a pill every day, people might soon control "bad" LDL cholesterol by getting an injection at their doctor's office two or three times a year. Researchers testing a new injectable drug called Inclisiran found it cut LDL cholesterol by half or more. According to early clinical trial data, the effect could last for four to six months. Inclisiran produced "significant and durable reductions in LDL cholesterol, and thus could potentially impact cardiovascular events," said study presenter Dr. Kausik Ray, a professor of public health at Imperial College London in England. Such long-lasting effects could provide a major advance in preventing heart disease, heart attack and stroke, by helping reduce hardening of the arteries, the researchers said. The trial results were presented Tuesday at the American Heart Association annual meeting in New ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Atorvastatin, Pravastatin, Zocor, Lovastatin, Rosuvastatin, High Cholesterol - Familial Heterozygous, Hypertriglyceridemia, Pravachol, Livalo, High Cholesterol - Familial Homozygous, Red Yeast Rice, Caduet, Repatha, Lescol, Hyperlipoproteinemia, Lescol XL

High-Dose Statins Boost Survival: Study

Posted 9 Nov 2016 by Drugs.com

WEDNESDAY, Nov. 9, 2016 – Higher doses of the cholesterol-lowering drugs known as statins appear to boost survival slightly for certain people, a large new study reports. The study followed more than 509,000 patients with various forms of cardiovascular disease. The researchers found that survival increased by 9 percent when people took high versus moderate doses of statin for a little over a year. High doses – also called high-intensity statin therapy – included 40 to 80 milligrams (mg) of atorvastatin (Lipitor) or 20 to 40 mg of rosuvastatin (Crestor) daily. Examples of moderate doses include 10 to 20 mg of Lipitor and 5 to 10 mg of Crestor, the study reported. Unlike some previous studies, this study included adults over age 75. The study showed that people over 75 also have a survival benefit with high doses compared to moderate doses, said study author Dr. Fatima Rodriguez. ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Atorvastatin, Pravastatin, Zocor, Lovastatin, Rosuvastatin, Pravachol, Prevention of Cardiovascular Disease, Livalo, Red Yeast Rice, Caduet, Cardiovascular Risk Reduction, Lescol, Lescol XL, Mevacor, Atorvastatin/Ezetimibe, Amlodipine/Atorvastatin, Liptruzet

'White Coat' High Blood Pressure May Signal Trouble in Older People

Posted 31 Oct 2016 by Drugs.com

MONDAY, Oct. 31, 2016 – So-called "white coat hypertension" is mostly harmless, but in some older people it may indicate a risk for heart disease, a new study suggests. White coat hypertension refers to high blood pressure readings in a doctor's office or other medical setting in people who typically have normal blood pressure. This study included 653 people with white coat hypertension and 653 with normal blood pressure. All of the study volunteers were followed for more than 10 years. During that time, there was no difference in the number of new heart problems in either group for people younger than 60. However, among 92 people aged 60 and older, there were 18 more new heart problem cases among those with white coat hypertension than in those without, according to researchers, led by Dr. Stanley Franklin from University of California, Irvine. Franklin's team said the findings ... Read more

Related support groups: High Blood Pressure, Hypertension, Azor, Exforge, Benicar HCT, Diovan HCT, Hyzaar, Lotrel, Avalide, Hydrochlorothiazide/Lisinopril, Micardis HCT, Tribenzor, Caduet, Ziac, Edarbyclor, Amlodipine/Benazepril, Tarka, Zestoretic, Twynsta, Hypertensive Emergency

Statins Often Interact With Other Heart Drugs

Posted 17 Oct 2016 by Drugs.com

MONDAY, Oct. 17, 2016 – Cholesterol-lowering statins can interact with other drugs prescribed for heart disease. But there are ways to navigate the problem, according to new recommendations from the American Heart Association. Statins are among the mostly widely prescribed drugs in the United States. Roughly one-quarter of Americans age 40 and up are on a statin, according to a 2014 study by the U.S. Centers for Disease Control and Prevention. The drugs are prescribed to people who either have atherosclerosis (clogged arteries) or are at risk of it, which means many statin users also take other cardiovascular drugs, the heart association says. The benefits of those drug combinations will generally outweigh the risks, said Barbara Wiggins, a clinical pharmacy specialist in cardiology at the Medical University of South Carolina. But doctors and patients should be aware of how the drugs ... Read more

Related support groups: Warfarin, Coumadin, Amlodipine, Lipitor, Simvastatin, Crestor, Diltiazem, Atorvastatin, Verapamil, Norvasc, Pravastatin, Amiodarone, Digoxin, Nifedipine, Cardizem, Zocor, Azor, Lovastatin, Exforge, Rosuvastatin

Are There Alternatives to Statins?

Posted 27 Sep 2016 by Drugs.com

TUESDAY, Sept. 27, 2016 – Statins are the go-to therapy for lowering "bad" LDL cholesterol, but other treatments also can effectively reduce risk of future heart problems, a new evidence review reports. These alternative therapies – including a heart-healthy diet, other cholesterol-lowering medications, and even intestinal bypass surgery – seem to confer the same level of heart health protection as statins when cholesterol levels decrease, according to the findings. Nonstatin therapies reduced the risk of heart problems by 25 percent for each 1 millimole per liter (mmol/L) decrease in LDL cholesterol levels. That's very similar to the 23 percent reduction per 1 mmol/L decrease seen with statins like atorvastatin (Lipitor) and simvastatin (Zocor), the researchers said. What's more, the benefits of these therapies stack up if more than one proves effective at lowering a person's ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Atorvastatin, Pravastatin, Welchol, Zocor, Cholestyramine, Lovastatin, Zetia, Vytorin, Rosuvastatin, Gastric Bypass Surgery, High Cholesterol - Familial Heterozygous, Hypertriglyceridemia, Questran, Pravachol, Livalo, High Cholesterol - Familial Homozygous

Tighter Blood Pressure Control Could Save 100,000 U.S. Lives: Study

Posted 15 Sep 2016 by Drugs.com

THURSDAY, Sept. 15, 2016 – Engaging Americans at high risk for heart disease in aggressive efforts to lower their blood pressure could save more than 100,000 lives a year, a new analysis indicates. Current guidelines recommend a systolic pressure – the top number in a blood pressure reading – of below 140 mm Hg. But a 2015 study from the U.S. National Institutes of Health suggested more lives could be saved if the goal was less than 120 mm Hg. The NIH trial known as SPRINT included adults aged 50 and older with systolic readings of 130 to 180 mm Hg and at high risk of heart disease (but not diabetes or stroke). They had either intensive treatment, with a goal of lowering systolic pressure to less than 120 mm Hg, or standard treatment, with a target of less than 140 mm Hg. The results were so impressive that the NIH halted the trial early. Risk of death from all causes was 27 percent ... Read more

Related support groups: High Blood Pressure, Hypertension, Metoprolol, Atenolol, Propranolol, Hydrochlorothiazide, Bystolic, Carvedilol, Bisoprolol, Inderal, Coreg, Sotalol, Azor, Toprol-XL, Exforge, Benicar HCT, Lopressor, Diovan HCT, Hyzaar, Timolol

Fewer Drugs in Pipeline to Treat World's No. 1 Killer

Posted 29 Aug 2016 by Drugs.com

MONDAY, Aug. 29, 2016 – Heart disease remains the world's leading cause of death, but development of drugs to treat it has slowed, a new study reveals. The percentage of heart drugs in clinical trials declined from 1990 through 2012, an analysis of pharmaceutical research and development projects found. Over that time period, 347 heart drugs entered clinical trials, most of them to treat high blood pressure, prevent clotting and lower lipid levels (such as cholesterol) in the blood. Clinical trials are done in a series of steps called phases, each intended to answer different questions about drugs' safety and effectiveness. Between 1990 and 1995, heart drugs made up 108 of 679 (16 percent) of phase 1 trials. That compared with 125 of 2,366 (5 percent) between 2005 and 2012, the researchers said. Phase 1 is the earliest stage of testing. Among later-stage, phase 3 trials, heart drugs ... Read more

Related support groups: Metoprolol, Heart Disease, Amlodipine, Atenolol, Hydrochlorothiazide, Diltiazem, Bystolic, Lasix, Verapamil, Norvasc, Furosemide, Bisoprolol, Nifedipine, Cardizem, Toprol-XL, Lopressor, Tenormin, Metoprolol Succinate ER, Felodipine, Chlorthalidone

Just a Little of Statins' Effect Enough to Help Heart: Study

Posted 20 Jun 2016 by Drugs.com

MONDAY, June 20, 2016 – Giving high doses of statins to patients with heart disease doesn't lower the risk of future heart trouble any more than moderate doses of the cholesterol-lowering drugs do, a new study finds. Having heart disease raises the risk of heart attack and stroke, as blood vessels become clogged and cut the normal flow of blood and oxygen to the heart. These patients are typically prescribed statins on a long-term basis, to lower levels of vessel-clogging LDL ("bad") cholesterol. But experts remain conflicted about exactly how low LDL cholesterol levels should go. "Our study demonstrates that physicians treating patients with heart disease and elevated levels of cholesterol with statins have to ensure that patients meet a target of less than 100 mg/dL to prevent future [heart] events," said study author Dr. Morton Leibowitz. He is a senior physician with the Clalit ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Atorvastatin, Pravastatin, Zocor, Lovastatin, Vytorin, Rosuvastatin, Pravachol, Livalo, Prevention of Cardiovascular Disease, Red Yeast Rice, Caduet, Cardiovascular Risk Reduction, Simcor, Lescol, Lescol XL, Mevacor

Statins Might Not Lower Colon Cancer Risk: Study

Posted 26 Apr 2016 by Drugs.com

TUESDAY, April 26, 2016 – Long-term use of cholesterol-lowering statins does not appear to reduce the risk of colon cancer, but a person's cholesterol levels might affect risk, a new study suggests. Both statins and cholesterol levels have been linked with lower colon cancer risk, but pinpointing which one is actually responsible has been difficult, the University of Pennsylvania researchers explained. So, they compared statin use and cholesterol levels in more than 22,000 British patients with colon cancer and more than 86,500 without the disease. The results confirmed findings from previous studies that showed a lower risk of colon cancer in people who take statins. But the risk was not significantly different between people who kept taking statins and those who stopped taking the drugs. Instead, the higher the cholesterol level, the lower the colon cancer risk for patients, ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Colonoscopy, Atorvastatin, Pravastatin, Colorectal Cancer, Zocor, Lovastatin, Vytorin, Rosuvastatin, Pravachol, Livalo, Red Yeast Rice, Caduet, Simcor, Lescol, Lescol XL, Mevacor

More Support for Lower Blood Pressure Goals

Posted 9 Dec 2015 by Drugs.com

WEDNESDAY, Dec. 9, 2015 – Intensive treatment to lower blood pressure below currently recommended levels reduces the risk of heart attack and stroke in patients with high blood pressure, heart disease, diabetes and kidney disease, a new study shows. Effective blood pressure goals have been the subject of much recent scientific debate, with another recent study also supporting lower targets. For this study, researchers analyzed data from 19 clinical trials that included nearly 45,000 people. They wanted to assess the potential benefits and safety of pushing systolic blood pressure in high-risk patients below the current target of 140. Systolic is the top number in a blood pressure reading. Compared to those who received standard treatment, average systolic pressure was 6.8 lower and diastolic blood pressure was 4.5 lower in patients who received more intensive treatment – 133.2/76.4 ... Read more

Related support groups: High Blood Pressure, Lisinopril, Hypertension, Metoprolol, Heart Disease, Atenolol, Heart Attack, Ischemic Stroke, Propranolol, Hydrochlorothiazide, Bystolic, Carvedilol, Renal Failure, Ramipril, Bisoprolol, Inderal, Coreg, Enalapril, Benazepril, Transient Ischemic Attack

Heart Disease Doesn't Take a Holiday

Posted 25 Nov 2015 by Drugs.com

WEDNESDAY, Nov. 25, 2015 – People with heart disease should take a number of precautions if they travel over the Thanksgiving holiday, an expert suggests. The first step is to be as well-prepared on your trip as you are at home, said Dr. Winston Gandy Jr., a cardiologist at Piedmont Heart Institute in Atlanta. "Make sure when you travel that you have your medicine," Gandy said in an American Heart Association news release. Some people carry a copy of their original prescriptions in case they lose their medications, but having a list of your medications and your cardiologist's phone number should be sufficient. It's also a good idea to tell your cardiologist where you'll be. "Chances are your cardiologist is going to know someone there, either personally or by reputation," who can provide you with help if needed, Gandy said. Research medical facilities at your destination, and know what ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Atorvastatin, Pravastatin, Niacin, Zocor, Niaspan, Azor, Lovastatin, Benicar HCT, Exforge, Diovan HCT, Hyzaar, Rosuvastatin, Lotrel, Avalide, Pravachol, Hydrochlorothiazide/Lisinopril, Livalo

Confirm High Blood Pressure Outside Doctor's Office, U.S. Task Force Says

Posted 12 Oct 2015 by Drugs.com

MONDAY, Oct. 12, 2015 – High blood pressure levels should generally be confirmed with home or ambulatory blood pressure monitoring before starting treatment for hypertension, a new U.S. Preventive Services Task Force (USPSTF) recommendation says. Many factors can affect blood pressure readings, such as stress, physical activity and caffeine or nicotine, the USPSTF said. And, some people experience "white-coat hypertension" – an increase in blood pressure at the doctor's office from stress – when having their blood pressure taken. All of these factors can make it hard to tell if someone really has high blood pressure, the researchers said. That's why the Task Force recommends confirming a diagnosis of high blood pressure, or hypertension, before starting treatment, unless someone has very high blood pressure that needs to be treated right away. "For most patients, elevated blood ... Read more

Related support groups: High Blood Pressure, Hypertension, Metoprolol, Atenolol, Propranolol, Bystolic, Carvedilol, Bisoprolol, Coreg, Inderal, Sotalol, Azor, Exforge, Toprol-XL, Benicar HCT, Lopressor, Diovan HCT, Hyzaar, Timolol, Lotrel

Page 1 2 Next

Ask a Question

Further Information

Related Condition Support Groups

High Cholesterol, High Blood Pressure, Hypertension, Prevention of Cardiovascular Disease, Coronary Artery Disease (CAD), Angina

Caduet Patient Information at Drugs.com