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FDA Approves Once-Weekly Bydureon BCise (exenatide) for Patients with Type-2 Diabetes

Posted 26 Oct 2017 by Drugs.com

23 October 2017 – AstraZeneca today announced that the US Food and Drug Administration (FDA) has approved Bydureon® BCise™ (exenatide extended-release) injectable suspension, a new formulation of Bydureon (exenatide extended-release) injectable suspension in an improved once-weekly, single-dose autoinjector device for adults with type-2 diabetes whose blood sugar remains uncontrolled on one or more oral medicines in addition to diet and exercise, to improve glycemic control. Unlike other glucagon-like peptide-1 (GLP-1) receptor agonists, Bydureon BCise has a unique, continuous-release microsphere delivery system designed to provide consistent therapeutic levels of the active ingredient, exenatide, to help patients reach and maintain steady state. The new formulation in the innovative Bydureon BCise device is proven to reduce blood sugar levels, with the added benefit of weight loss, al ... Read more

Related support groups: Diabetes, Type 2, Bydureon, Diabetes Mellitus, Exenatide

Flu Shot Key for People With Diabetes

Posted 8 Oct 2017 by Drugs.com

SUNDAY, Oct. 8, 2017 – With predictions calling for a potentially bad flu season this year, doctors are urging people – particularly those with diabetes – to get vaccinated. Many people with diabetes don't get a seasonal flu shot each year, according to the American Association of Diabetes Educators (AADE). Some people with the blood sugar disease don't realize they're at risk for flu-related complications. Others have misguided fears that the shot will trigger an adverse reaction, the group explained. However, people with diabetes are more likely to develop serious flu-related health problems if they get the virus, the AADE cautioned. The group said the flu shot is a safe and effective way to prevent or reduce the severity of these complications. "Reducing risks is one of the AADE's seven key self-care behaviors for managing diabetes, and getting the flu shot every fall is an ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Victoza, Lantus, Saxenda, Diabetes, Type 1, Glipizide, Novolog, Januvia, Insulin Resistance, Humalog, Glucophage, Bydureon, Invokana, Trulicity, Janumet, Glyburide, Lantus Solostar, Levemir

Heart Health Ignored by Many With Type 2 Diabetes

Posted 8 Aug 2017 by Drugs.com

TUESDAY, Aug. 8, 2017 – Taking steps to prevent heart disease is crucial for people with type 2 diabetes. But most diabetic adults in the United States aren't meeting recommended guidelines, health officials say. In a new report, researchers confirm that "cardiovascular risk reduction is critically important for the care of patients with diabetes, with or without known [heart disease or heart disease] risk factors." Drugs such as cholesterol-lowering statins, aspirin and blood sugar-lowering medications plus lifestyle approaches should be considered for all type 2 diabetes patients, according to the Aug. 7 report in the Journal of the American College of Cardiology. Suggested lifestyle approaches include exercise, good nutrition and weight management. For the report, researchers from New York University Medical Center examined evidence behind the guidelines for preventing heart disease ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Heart Disease, Victoza, Lantus, Saxenda, Glipizide, Novolog, Januvia, Humalog, Glucophage, Bydureon, Invokana, Trulicity, Janumet, Glyburide, Lantus Solostar, Byetta, Levemir

Online Game Helps Those With Diabetes Control Blood Sugar

Posted 8 Aug 2017 by Drugs.com

TUESDAY, Aug. 8, 2017 – Here's another example of technology's evolving impact on health care. A new study found that playing an online game can help those with diabetes get better control of their blood sugar. The study included 456 U.S. Veterans Affairs diabetes patients with poor blood sugar control while on oral medications. Half played a specially designed, team-based online diabetes education game for six months. The others were assigned to a control group that played a civics education game. "This [diabetes control] game represents a small time commitment for patients, but potentially a big impact for their health," corresponding author Dr. B. Price Kerfoot said in a news release from Brigham and Women's Hospital in Boston. He is an associate professor of surgery at the hospital. The diabetes game features multiple choice questions about blood sugar control, exercise, long-term ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Victoza, Lantus, Saxenda, Diabetes, Type 1, Glipizide, Novolog, Januvia, Insulin Resistance, Hypoglycemia, Humalog, Glucophage, Bydureon, Invokana, Trulicity, Janumet, Glyburide, Lantus Solostar

Diabetes Drug, Exenatide, Shows Promise Against Parkinson's

Posted 4 Aug 2017 by Drugs.com

FRIDAY, Aug. 4, 2017 – The diabetes drug exenatide (Byetta) may do double duty as a treatment for Parkinson's disease, a new study suggests. "This is a very promising finding, as the drug holds potential to affect the course of the disease itself, and not merely the symptoms," said senior study author Tom Foltynie, from University College London's Institute of Neurology. "With existing treatments, we can relieve most of the symptoms [of Parkinson's] for some years, but the disease continues to worsen," he said in a university news release. "This is the strongest evidence we have so far that a drug could do more than provide symptom relief for Parkinson's disease." Parkinson's is the second most common neurodegenerative disease worldwide, the researchers noted. The condition results in muscle stiffness, slowed movement, tremors, sleep disturbance and chronic fatigue. In the study, 60 ... Read more

Related support groups: Parkinson's Disease, Bydureon, Byetta, Parkinsonism, Parkinsonian Tremor, Exenatide, Parkinson's Disease Psychosis

Intensive Type 2 Diabetes Treatment Can Extend Survival: Study

Posted 8 Sep 2016 by Drugs.com

WEDNESDAY, Sept. 7, 2016 – Intensive management of type 2 diabetes can make a difference in how long and how well you live, even if you don't start until middle age, researchers report. People who were already at risk of type 2 diabetes complications were randomly selected to continue with their normal treatment or to be placed in an aggressive and multipronged treatment group. Two decades after the study began, the researchers found that people in the aggressive treatment group lived almost eight years longer. Not only that, they lived better – their risk of heart disease, kidney disease and blindness all dropped. The only complication that didn't seem to improve was nerve damage caused by diabetes. "Early, intensified intervention in type 2 diabetes patients with microalbuminuria with both target-driven pharmacological (medication) and behavioral actions increased life span. And, ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Victoza, Lantus, Saxenda, Glipizide, Novolog, Januvia, Humalog, Glucophage, Bydureon, Invokana, Trulicity, Janumet, Glyburide, Lantus Solostar, Byetta, Levemir, Actos

FDA OKs New Injectable Type 2 Diabetes Medication

Posted 28 Jul 2016 by Drugs.com

THURSDAY, July 28, 2016 – The injectable drug Adlyxin (lixisenatide) has been approved to treat adults with type 2 diabetes, the U.S. Food and Drug Administration says. The once-daily injection is to be used along with diet and exercise to improve patients' blood sugar levels. The FDA reviewed 10 clinical trials on the safety and effectiveness of Adlyxin. These studies included 5,400 people with type 2 diabetes. The drug was also specifically tested for heart issues in an additional 6,000 people at risk of heart disease, the FDA said Thursday in a news release. The FDA concluded that Adlyxin helps normalize blood sugar levels. And it doesn't appear to increase the risk of heart problems. Adlyxin is in a class of drugs called glucagon-like peptide-1 (GLP-1) receptor agonists. Other GLP-1 drugs include liraglutide (Victoza), exenatide (Byetta, Bydureon) and dulaglutide (Trulicity), ... Read more

Related support groups: Diabetes, Type 2, Victoza, Saxenda, Insulin Resistance, Bydureon, Trulicity, Byetta, Pre-Diabetes, Liraglutide, Diabetes Mellitus, Dulaglutide, Exenatide, Adlyxin, Abnormal Glucose Tolerance, Lixisenatide

Cost of Insulin Rises Threefold in Just a Decade: Study

Posted 5 Apr 2016 by Drugs.com

TUESDAY, April 5, 2016 – Americans with diabetes who rely on insulin to keep their blood sugar levels in check are facing sticker shock: A new study finds the price of insulin has tripled in only 10 years. Moreover, since 2010, per-person spending on insulin in the United States was more than spending on all other diabetes drugs, the study found. "The cost of insulin has risen rapidly over the last few years," said study senior author Philip Clarke, a professor of health economics at the University of Melbourne in Australia. Clarke added there should be an assessment to see whether this price hike is justifiable in terms of improved clinical outcomes. One reason for the price climb, he said, is a switch from human insulins to analog insulins, which cost more but may offer additional benefits. Also, doctors are more apt to prescribe insulin for people with type 2 diabetes now, Clarke ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Victoza, Lantus, Saxenda, Diabetes, Type 1, Diabetic Neuropathy, Glipizide, Novolog, Januvia, Insulin Resistance, Humalog, Diabetic Nerve Damage, Glucophage, Bydureon, Invokana, Trulicity, Janumet, Glyburide

New Diabetes Cases Among Americans Drop for First Time in Decades: CDC

Posted 1 Dec 2015 by Drugs.com

TUESDAY, Dec. 1, 2015 – In a sign that Americans may finally be turning the corner in the fight against diabetes – and possibly obesity – federal health statistics released Tuesday show that the number of new cases of diabetes has dropped for the first time in decades. The decline wasn't sudden or dramatic. But, the number of new diabetes cases went from 1.7 million in 2009 to 1.4 million in 2014, according to the U.S. Centers for Disease Control and Prevention. "It seems pretty clear that incidence rates have now actually started to drop. Initially it was a little surprising because I had become so used to seeing increases everywhere we looked," CDC researcher Edward Gregg told The New York Times. The proportion of Americans with diabetes is still twice what it was in the early 1990s. And not every racial group has made strides against the blood sugar disease, which is often ... Read more

Related support groups: Obesity, Diabetes, Type 2, Metformin, Weight Loss, Insulin, Victoza, Lantus, Saxenda, Glipizide, Novolog, Januvia, Humalog, Glucophage, Bydureon, Invokana, Trulicity, Janumet, Glyburide, Lantus Solostar, Byetta

Too Many Seniors With Diabetes Are Overtreated, Study Suggests

Posted 29 Oct 2015 by Drugs.com

THURSDAY, Oct. 29, 2015 – When it comes to treating seniors with diabetes, new research suggests that doctors often don't cut back on medications, even when treatment goals are surpassed. The study found that when people had potentially dangerous low blood sugar levels, just 27 percent had their medicines decreased. And when blood pressure treatments lowered blood pressure levels too much, just 19 percent saw a reduction in their medications. "As people get older, the risks of overtreating become greater, and the benefits become shorter. We have to start emphasizing that more isn't always better," said study author Dr. Jeremy Sussman, an assistant professor of internal medicine at the University of Michigan in Ann Arbor and a primary care doctor at the Ann Arbor VA System. The findings were published online Oct. 26 in the journal JAMA Internal Medicine. Practice guidelines generally ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Victoza, Lantus, Saxenda, Glipizide, Novolog, Januvia, Humalog, Glucophage, Bydureon, Invokana, Trulicity, Janumet, Glyburide, Lantus Solostar, Byetta, Levemir, Actos

Health Tip: Diabetes Can Take a Toll on Teeth and Mouth

Posted 10 Aug 2015 by Drugs.com

-- Diabetes, especially when uncontrolled, can cause damage to your mouth and teeth. The Mouthhealthy.org website says possible effects of diabetes on the teeth and mouth include: Dry mouth, due to decreased saliva production. Increased risk of cavities due to less saliva. Gingivitis, characterized by bleeding, inflamed gums. Difficulty tasting food. Slower healing of mouth wounds. Increased risk of infection. Among diabetic children. teeth emerging earlier than expected. Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Victoza, Xerostomia, Oral and Dental Conditions, Toothache, Lantus, Saxenda, Diabetes, Type 1, Diabetic Neuropathy, Burning Mouth Syndrome, Glipizide, Novolog, Januvia, Insulin Resistance, Humalog, Diabetic Nerve Damage, Glucophage, Bydureon

People With Type 2 Diabetes Do Benefit From Blood Sugar Checks

Posted 5 Aug 2015 by Drugs.com

WEDNESDAY, Aug. 5, 2015 – Personalized blood sugar self-monitoring benefits people with type 2 diabetes even if they're not taking insulin, a new small study shows. Some experts have questioned the value of self-monitoring in this group, and many insurers – including Medicare – limit the reimbursement of blood sugar (glucose) testing strips to one a day for people with type 2 diabetes. This study included 11 people with type 2 diabetes who worked with the researchers to create personalized, structured self-monitoring blood glucose schedules. In most cases, self-monitoring twice a day was the most helpful in providing meaningful information about blood sugar levels. However, there was room for individualization based on a patient's type of lifestyle and needs. For example, a patient might check their blood sugar twice a day three days a week instead of once a day seven days a week, ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Victoza, Lantus, Saxenda, Glipizide, Novolog, Januvia, Humalog, Glucophage, Bydureon, Invokana, Trulicity, Janumet, Glyburide, Lantus Solostar, Byetta, Levemir, Actos

Certain Diabetes Drugs May Aid Weight Loss by Curbing Cravings

Posted 9 Jun 2015 by Drugs.com

TUESDAY, June 9, 2015 – A class of drugs used to treat diabetes also appears to help patients lose weight by changing how the brain responds to food, a new study suggests. Researchers have been trying to learn how gut-hormone based medications called GLP-1 receptor agonists also help people with type 2 diabetes shed excess pounds. A Dutch team said the drugs may reduce cravings and increase satisfaction while eating. The researchers looked specifically at the injectable GLP-1 receptor agonist exenatide (Bydureon, Byetta). Their findings are to be presented Tuesday at the American Diabetes Association (ADA) annual meeting in Boston. Studies presented at meetings are generally viewed as preliminary until they've been published in a peer-reviewed journal. "When you eat, there are several hormones released. GLP-1 is one of them," Dr. Liselotte van Bloemendaal, a Ph.D. student at the ... Read more

Related support groups: Obesity, Diabetes, Type 2, Weight Loss, Bydureon, Byetta, Exenatide

FDA Approves Bydureon Pen for Once-Weekly Treatment of Adults with Type 2 Diabetes

Posted 6 Mar 2014 by Drugs.com

Monday March 3, 2014 – AstraZeneca today announced that the U.S. Food and Drug Administration (FDA) has approved the Bydureon Pen (exenatide extended-release for injectable suspension) 2 mg as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes. Bydureon should not be used for treatment of patients with type 1 diabetes or diabetic ketoacidosis. Bydureon is not recommended as first-line therapy for patients who have inadequate glycemic control on diet and exercise. Bydureon is not a substitute for insulin. The concurrent use of Bydureon with insulin has not been studied and is not recommended. Bydureon is the first and only once-weekly medicine for adults with type 2 diabetes. The Bydureon Pen is a pre-filled, single-use pen injector, eliminating the need for the patient to transfer the medication between a vial and syringe during the ... Read more

Related support groups: Diabetes, Type 2, Bydureon, Exenatide

Study Sees No Evidence Linking Diabetes Drugs With Pancreatic Cancer

Posted 26 Feb 2014 by Drugs.com

WEDNESDAY, Feb. 26, 2014 – There's no firm evidence that the type 2 diabetes medications known as incretin-based drugs cause pancreatitis or pancreatic cancer, U.S. and European health officials say. But it's too early to say there's definitely no link between the injectable drugs and pancreatitis or pancreatic cancer, according to the safety assessment by the U.S. Food and Drug Administration (FDA) and its counterpart overseas, the European Medicines Agency (EMA). "Both agencies agree that assertions concerning a causal association between incretin-based drugs and pancreatitis or pancreatic cancer, as expressed recently in the scientific literature and in the media, are inconsistent with the current data," states the report in the Feb. 27 issue of the New England Journal of Medicine. "The FDA and the EMA have not reached a final conclusion at this time regarding such a causal ... Read more

Related support groups: Victoza, Januvia, Pancreatitis, Bydureon, Byetta, Liraglutide, Pancreatic Cancer, Onglyza, Sitagliptin, Saxagliptin, Exenatide

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