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Bevacizumab News

For Seniors, Treatment for One Eye Disease May Cause Another

Posted 16 Mar 2017 by Drugs.com

THURSDAY, March 16, 2017 – Drugs that preserve vision in people with the eye disease called age-related macular degeneration might increase the risk of another eye condition – glaucoma, a new study suggests. People who received at least seven eye injections of the drug bevacizumab (Avastin) each year to treat macular degeneration have a higher risk of eventually needing surgery to treat glaucoma, the Canadian study found. But, the researchers aren't suggesting that people forgo these treatments for macular degeneration. These drugs help stave off a previously untreatable cause of blindness in the elderly, and should continue to be used, the researchers said. And, if glaucoma does develop, treatments are available. "Even though there may be a risk here, this doesn't mean you should not be getting injections for macular degeneration," said study lead author Dr. Brennan Eadie. He's an ... Read more

Related support groups: Eye Conditions, Glaucoma, Glaucoma (Open Angle), Votrient, Macular Degeneration, Avastin, Sutent, Nexavar, Pazopanib, Stivarga, Sunitinib, Glaucoma/Intraocular Hypertension, Retinal Disorders, Sorafenib, Cyramza, Bevacizumab, Inlyta, Ramucirumab, Vandetanib, Cabometyx

Chemo Drug May Combat Serious Brain Tumor After All

Posted 22 Dec 2016 by Drugs.com

THURSDAY, Dec. 22, 2016 – Some patients with a deadly brain tumor may respond to drugs previously believed to be ineffective against the cancer, a new study says. The findings highlight the importance of properly categorizing glioblastoma tumors in order to best tailor treatment to each patient, according to the researchers. Glioblastoma tumors are diagnosed in about 12,000 people in the United States each year. Half of patients with this type of tumor die within 15 months of diagnosis, the researchers said. There was hope that lives could be extended with a class of chemotherapy drugs called anti-angiogenic compounds. These drugs were designed to block the growth of new blood vessels in the tumor in an attempt to starve the tumor of oxygen and nutrients. But recently published findings from two large clinical trials concluded that an anti-angiogenic drug called bevacizumab did not ... Read more

Related support groups: Cancer, Brain Tumor, Avastin, Glioblastoma Multiforme, Bevacizumab

FDA Approves Avastin (bevacizumab) Plus Chemotherapy for a Specific Type of Advanced Ovarian Cancer

Posted 7 Dec 2016 by Drugs.com

South San Francisco, CA – December 6, 2016 – Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), today announced that the U.S. Food and Drug Administration (FDA) has approved Avastin (bevacizumab), either in combination with carboplatin and paclitaxel or in combination with carboplatin and gemcitabine chemotherapy, followed by Avastin alone, for the treatment of patients with platinum-sensitive recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer. Women are said to have a ‘platinum-sensitive’ form of the disease if a relapse occurs six months or longer following the last treatment with a platinum-based chemotherapy. “With today’s approval of Avastin plus chemotherapy, women in the U.S. with recurrent, platinum-sensitive ovarian cancer now have a treatment option that showed a survival difference of more than five months compared to chemotherapy al ... Read more

Related support groups: Avastin, Ovarian Cancer, Bevacizumab, Fallopian Tube Cancer, Peritoneal Cancer

Salt-Based Spray May Help Chronic Nosebleeds

Posted 6 Sep 2016 by Drugs.com

TUESDAY, Sept. 6, 2016 – A simple salt-based spray is as effective as medicated sprays in controlling chronic nosebleeds, a new study contends. "This research highlights that there could be a benefit even in the simplest of interventions," said corresponding study author Dr. Kevin Whitehead. He is an associate professor of internal medicine at the University of Utah School of Medicine. People with a condition called hemorrhagic telangiectasia (HHT) are plagued with nosebleeds. Many have one nosebleed a week, and some have more than two a day. The new study included 121 people with the condition who sprayed either a saline solution (salt plus water) or one of three medications – bevacizumab, estriol or tranexamic acid – into their nose twice a day for 12 weeks. The saline spray was as effective in reducing nosebleeds as the drugs, according to the study. "No drug proved to be any ... Read more

Related support groups: Bleeding Disorder, Avastin, Tranexamic Acid, Lysteda, Bevacizumab, Cyklokapron, Rhinaris, ENTsol, Saline Nasal Mist, Ayr Saline Nasal, Little Noses, Humist, Neilmed Nasogel, Ocean, Ocean Kids, Pediamist, Sea Soft, NasoGel, Afrin Saline, Simply Soothing

Cancer's Heavy Financial Burden

Posted 8 Jun 2016 by Drugs.com

WEDNESDAY, June 8, 2016 – Many cancer patients can't afford to see their doctor or take the medications they've been prescribed, a new study finds. And the problem will likely only get worse as the cost of cancer treatments continues to rise, the study authors said. "You can prescribe the best drug in the world, but if patients can't afford it and they can't get it, then it won't be effective," said study author Dr. Greg Knight. He is chief fellow with the University of North Carolina School of Medicine's division of hematology and oncology. "We saw a significant portion of patients in our study who were stretching their prescriptions or not coming to the doctor's office," Knight said in a university news release. The researchers reviewed survey results from nearly 2,000 patients at the N.C. Cancer Hospital in Chapel Hill, N.C. The participants were all 18 and older, and had been ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Gleevec, Lung Cancer, Colorectal Cancer, Votrient, Brain Tumor, Tarceva, Avastin, Melanoma, Skin Cancer, Tasigna, Ovarian Cancer, Sutent, Endometrial Cancer, Herceptin, Sprycel, Afinitor, Nausea/Vomiting - Chemotherapy Induced

U.S. Pays Highest Prices for Cancer Meds: Study

Posted 6 Jun 2016 by Drugs.com

MONDAY, June 6, 2016 – The United States pays the highest prices in the world for generic and brand-name cancer drugs, a new study has found. However, as the world's wealthiest nation, the United States is better able to pay for those pricey drugs than poorer countries with somewhat lower medication prices, added study lead author Dr. Daniel Goldstein. People in China and India are much less able to afford cancer drugs than Americans, he said, even though U.S. monthly drug prices are about three to six times higher in the United States. That doesn't mean America came out on top in overall drug affordability, however. Developed nations such as Australia, England and Israel had the "best deal" in the world on cancer drugs, thanks to government programs that regulate drug pricing, the study found. "America is the wealthiest nation, but its drug prices are significantly higher – so much ... Read more

Related support groups: Cancer, Depo-Provera, Provera, Methotrexate, Breast Cancer, Accutane, Lupron, Medroxyprogesterone, Tamoxifen, Arimidex, Tretinoin, Fluorouracil, Lupron Depot, Femara, Gleevec, Lung Cancer, Rituxan, Isotretinoin, Colorectal Cancer, Votrient

Tumor Location Affects Colon Cancer Survival: Study

Posted 19 May 2016 by Drugs.com

WEDNESDAY, May 18, 2016 – Your survival odds against colon cancer may depend on which side of your colon the tumor develops, new research contends. In a study of more than 1,000 men and women with colon cancer that had spread, those whose tumor was on the left side survived just over 33 months, while those whose tumor was on the right side survived only slightly more than 19 months. "It's a stunning and surprising finding, and the difference is dramatic," said lead researcher Dr. Alan Venook, a professor of medicine at the University of California, San Francisco. It appears that colon cancer that begins on the right side is different from colon cancer that begins on the left side, he said. "We thought of the colon as a tube that propelled stool out of the body, but it's not that simple," Venook said. "Each side of the colon starts in a different place, which is why the cancers are ... Read more

Related support groups: Colonoscopy, Colorectal Cancer, Avastin, Erbitux, Bevacizumab, Cetuximab, Familial Adenomatous Polyposis

Drug Used for Preemie Eye Disease Tied to Disabilities

Posted 19 Mar 2016 by Drugs.com

FRIDAY, March 18, 2016 – A drug used to treat an eye disease in premature infants may be linked to serious disabilities such as cerebral palsy and hearing loss, a new study suggests. The drug in question is Avastin (bevacizumab), a cancer drug that fights tumors by cutting off their blood supply. In the past few years, doctors have also been using it to treat retinopathy of prematurity, or ROP. Avastin isn't approved by the U.S. Food and Drug Administration specifically to treat ROP, but doctors still use the drug for what's known as an "off-label" indication. The current findings do not prove that Avastin is to blame, according to the researchers, led by Dr. Julie Morin of the Sainte-Justine University Hospital Center, in Montreal, Canada. They only show an association between the drug and serious complications in babies treated for ROP. ROP is a potentially blinding disease that ... Read more

Related support groups: Eye Conditions, Avastin, Bevacizumab

Study Compares Drugs for Common Diabetic Eye Disease

Posted 29 Feb 2016 by Drugs.com

MONDAY, Feb. 29, 2016 – People with diabetes are at risk for blurred vision or even a loss of vision from a condition called macular edema. Three drugs for the disease – Avastin, Eylea and Lucentis – vary widely in price, but new research suggests all work equally well for patients with mild vision loss. However, when diabetic macular edema leads to more severe vision loss, researchers found Eylea to be the better choice. The study, funded by the U.S. National Eye Institute (NEI), "will help doctors and their patients with diabetic macular edema choose the most appropriate therapy," study lead author Dr. John Wells said in an institute news release. "The study suggests there is little advantage of choosing Eylea or Lucentis over [much cheaper] Avastin when a patient's loss of visual acuity from macular edema is mild, meaning a visual acuity of 20/40 or better," Wells explained. ... Read more

Related support groups: Eye Conditions, Macular Degeneration, Avastin, Diabetes Mellitus, Lucentis, Macular Edema, Eylea, Abnormal Glucose Tolerance, Bevacizumab, Diabetic Macular Edema, Visual Defect/Disturbance, Ranibizumab, Aflibercept

Drug Avastin Not Linked to Higher Risk of Blindness: Study

Posted 13 Aug 2015 by Drugs.com

THURSDAY, Aug. 13, 2015 – Concerns that eye injections of the drug Avastin increase the risk of a potentially blinding eye infection may be unfounded, a new study finds. Researchers analyzed insurance claims data from across the United States to compare the use of Avastin (bevacizumab) to treat retinal diseases with a much more expensive drug called Lucentis (ranibizumab). The study was conducted in response to reports of Avastin-related eye infections that led the U.S. Food and Drug Administration to propose tight restrictions on the use of the drug for eye conditions. But the findings showed that patients treated with Avastin do not have a higher risk of an eye infection called endophthalmitis than those treated with Lucentis, the study authors said. The researchers looked at more than 296,000 injections of Avastin and more than 87,000 injections of Lucentis. They found the rates of ... Read more

Related support groups: Eye Conditions, Avastin, Lucentis, Bevacizumab, Orbital Infection, Infectious Endophthalmitis, Ranibizumab

U.S. Oncologists Decry High Cost of Cancer Drugs

Posted 23 Jul 2015 by Drugs.com

THURSDAY, July 23, 2015 – Soaring costs for cancer drugs are hurting patient care in the United States, a group of top oncologists claim. "High cancer-drug prices are affecting the care of patients with cancer and our health care system," Dr. Ayalew Tefferi, a hematologist at Mayo Clinic in Rochester, Minn., said in a Mayo news release. Tefferi and his colleagues made a number of recommendations on how to address the problem in a commentary published July 23 in the Mayo Clinic Proceedings. Allowing Medicare to negotiate drug prices is one of the suggestions the team of 118 leading cancer experts offered as a possible solution. Along with their recommendations, the group also expressed support for a patient-based grassroots movement on change.org that is demanding action on the issue. "The average gross household income in the U.S. is about $52,000 per year. For an insured patient with ... Read more

Related support groups: Cancer, Depo-Provera, Provera, Methotrexate, Breast Cancer, Accutane, Lupron, Prostate Cancer, Medroxyprogesterone, Tamoxifen, Arimidex, Tretinoin, Fluorouracil, Lupron Depot, Femara, Gleevec, Lung Cancer, Rituxan, Renal Cell Carcinoma, Isotretinoin

Chemo for Breast Cancer Erases Woman's Fingerprints

Posted 16 Apr 2015 by Drugs.com

WEDNESDAY, April 15, 2015 – A 65-year-old breast cancer patient ran into an unexpected problem with her bank: She was denied a transaction because her fingerprints had disappeared. Reporting in the April 16 issue of the New England Journal of Medicine, doctors in Mexico said the woman's unusual case was due to the effects of chemotherapy for an advanced breast cancer that had spread to the lungs. A chemotherapy side effect called "hand-foot syndrome" appears to be tied to the fingerprint loss, wrote Drs. Yanin Chavarri-Guerra and Enrique Soto-Perez-de-Celis, of the Institute of Medical Science and Nutrition in Mexico City. They described the syndrome as "characterized by redness, swelling, and pain on the palms of the hands or soles of the feet." The patient in question experienced hand-foot syndrome that was so bad it interfered with everyday tasks, the two physicians said. "Loss of ... Read more

Related support groups: Cancer, Breast Cancer, Avastin, Xeloda, Capecitabine, Breast Cancer - Palliative, Bevacizumab

Progress Reported in Battling Advanced Ovarian Cancer

Posted 29 Mar 2015 by Drugs.com

SATURDAY, March 28, 2015 – An experimental vaccine and a drug already on the market each may help slow down advanced ovarian cancer, two new studies suggest. In one, of just 31 patients, researchers found that adding the vaccine to standard treatment staved off a recurrence in women who had advanced-stage ovarian cancer. The other study, involving women with recurrent ovarian cancer, found that administering the drug Avastin after surgery and chemotherapy stalled the cancer's progression, versus surgery and chemo alone. The findings are to be presented Saturday at the annual meeting of the Society of Gynecologic Oncology (SGO), in Chicago. Studies reported at meetings are usually considered preliminary until they're published in a medical journal. Still, experts expressed cautious optimism, saying the findings represent progress against the deadliest form of gynecologic cancer. There ... Read more

Related support groups: Avastin, Ovarian Cancer, Bevacizumab

Vitamin D May Boost Colon Cancer Survival, Study Finds

Posted 12 Jan 2015 by Drugs.com

MONDAY, Jan. 12, 2015 – Higher vitamin D levels in patients with advanced colon cancer appear to improve response to chemotherapy and targeted anti-cancer drugs, researchers say. "We found that patients who had vitamin D levels at the highest category had improved survival and improved progression-free survival, compared with patients in the lowest category," said lead author Dr. Kimmie Ng, an assistant professor of medicine at Harvard Medical School in Boston. Those patients survived one-third longer than patients with low levels of vitamin D – an average 32.6 months, compared with 24.5 months, the researchers found. The report, scheduled for presentation this week at the Gastrointestinal Cancers Symposium in San Francisco, adds more weight to suspicions that vitamin D might be a valuable cancer-fighting supplement. However, colon cancer patients shouldn't try to boost vitamin D ... Read more

Related support groups: Colorectal Cancer, Avastin, Erbitux, Bevacizumab, Cetuximab

FDA Approves Avastin (bevacizumab) Plus Chemotherapy for Platinum-Resistant Recurrent Ovarian Cancer

Posted 16 Nov 2014 by Drugs.com

South San Francisco, Calif. – November 14, 2014 – Genentech, a member of the Roche Group, today announced that the U.S. Food and Drug Administration (FDA) approved Avastin in combination with chemotherapy for the treatment of women with platinum-resistant, recurrent ovarian cancer. The approval was based on results from the Phase III AURELIA study that showed Avastin plus chemotherapy reduced the risk of disease worsening or death (progression-free survival or PFS) by 62 percent compared to women who received chemotherapy alone (median PFS: 6.8 vs. 3.4 months, Hazard Ratio (HR)=0.38; p Read more

Related support groups: Avastin, Ovarian Cancer, Bevacizumab

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