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Swiss Report Highlights Danger of Drug-Resistant Tuberculosis

Posted 11 Nov 2015 by Drugs.com

WEDNESDAY, Nov. 11, 2015 – A new report on a patient in Switzerland who nearly died after catching a highly drug-resistant strain of tuberculosis illustrates exactly what public health officials around the world fear most. Although antibiotics have largely eradicated tuberculosis in the United States in recent decades, experts say evidence is mounting that the bacteria is becoming increasingly resistant to these medications. Details of the Swiss case are reported in the Nov. 12 issue of the New England Journal of Medicine by lead investigator Sebastien Gagneux, head of tuberculosis research with the Swiss Tropical and Public Health Institute at the University of Basel, and colleagues. Normally, Gagneux said, tuberculosis patients are treated for six months with a daily drug "cocktail" comprised of four different first-line medications. The goal: to hem in tuberculosis (TB) while ... Read more

Related support groups: Tuberculosis, Tuberculosis - Latent, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Tuberculosis - Extrapulmonary, Tuberculous Meningitis, Tuberculosis - Resistant, Tuberculous Pleurisy, Bedaquiline, Tuberculous Esophagitis, Adrenal Tuberculosis, Sirturo, Tuberculosis - Urinary Tract, Ocular Tuberculosis

Sirturo Approved for Multi-Drug Resistant TB

Posted 2 Jan 2013 by Drugs.com

WEDNESDAY, Jan. 2 – Sirturo (bedaquiline) has been approved by the U.S. Food and Drug Administration for use with other drugs to treat multi-drug resistant tuberculosis when alternative treatments aren't available. TB, which is spread through the air, is among the world's deadliest respiratory diseases. Nearly 9 million people worldwide and more than 10,000 in the United States contracted the disease in 2011, the agency said in a news release. The bacterium that causes TB, M. tuberculosis, has become resistant to the powerful drugs isoniazid and rifampin, the FDA added. Sirturo is the first drug approved to treat multi-drug resistant TB, the agency said in its news release. The drug inhibits an enzyme that makes it possible for the tuberculosis bacterium to replicate throughout the body. "Multi-drug resistant tuberculosis poses a serious health threat throughout the world, and Sirturo ... Read more

Related support groups: Tuberculosis - Resistant, Bedaquiline

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