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Study Suggests Heartburn Meds-Superbug Infections Link

Posted 27 Mar 2017 by Drugs.com

MONDAY, March 27, 2017 – Patients who take certain heartburn medications may be more likely to suffer recurrent bouts of a common "superbug" infection, a new study suggests. Proton pump inhibitors, such as Prilosec, Prevacid and Nexium, or so-called H2 blockers, such as Zantac, Pepcid and Tagamet, were linked to a 50 percent increased risk of developing multiple Clostridium difficile infections, researchers found. However, the study did not prove these heartburn medications cause recurrent C. difficile infections, just that an association appears to exist. And one specialist not involved with the study said the findings won't make him change his prescribing patterns. C. difficile can cause diarrhea and life-threatening inflammation of the colon. In the United States, about half a million people get sick from C. difficile each year. In recent years, these infections have become more ... Read more

Related support groups: Infections, GERD, Bacterial Infection, Omeprazole, Nexium, Prilosec, Pantoprazole, Protonix, Zantac, Ranitidine, Dexilant, Lansoprazole, Prevacid, Pepcid, Barrett's Esophagus, Aciphex, Famotidine, Heartburn Relief, Rabeprazole, Esomeprazole

Are Heartburn Meds During Pregnancy Linked to Asthma in Kids?

Posted 9 Jan 2017 by Drugs.com

MONDAY, Jan. 9, 2017 – Women who take certain heartburn medications during pregnancy may have a child at increased risk of developing asthma, new research suggests. For the new study, investigators analyzed eight studies that included more than 1.3 million children. The researchers found that kids born to mothers who were prescribed drugs for acid reflux during pregnancy were at least one-third more likely to have been seen by a doctor for asthma symptoms. Some of the medications come from drug classes that include Tagamet, Zantac, Prilosec, Nexium and Pepcid. "Our study reports an association between the onset of asthma in children and their mothers' use of acid-suppressing medication during pregnancy," said researcher Dr. Aziz Sheikh. He's co-director of the Asthma UK Center for Applied Research, at the University of Edinburgh in Scotland. "It is important to stress that this ... Read more

Related support groups: GERD, Asthma, Omeprazole, Nexium, Asthma - Maintenance, Prilosec, Pantoprazole, Zantac, Protonix, Indigestion, Ranitidine, Dexilant, Lansoprazole, Prevacid, Pepcid, Delivery, Asthma - Acute, Aciphex, Duodenitis/Gastritis, Famotidine

Heartburn Drugs May Raise Risk of Stomach Infections: Study

Posted 5 Jan 2017 by Drugs.com

THURSDAY, Jan. 5, 2017 – People who take heartburn drugs such as Prilosec and Nexium may be at increased risk of two potentially serious gut infections, a new study suggests. The study, of nearly 565,000 adults, found those on certain heartburn drugs had higher risks of infection with C. difficile and Campylobacter bacteria. Both bugs cause abdominal pain and diarrhea, but can become more serious – especially C. diff. According to the U.S. Centers for Disease Control and Prevention, almost half a million Americans were sickened by the infection in 2011, and 29,000 of them died within a month. The heartburn drugs in question included both proton pump inhibitors (PPIs) – brands like Prilosec, Prevacid and Nexium – and H2 blockers, such as Zantac, Pepcid and Tagamet, the study authors said. All suppress stomach acid production, and the researchers suspect that may make some people more ... Read more

Related support groups: GERD, Omeprazole, Nexium, Prilosec, Pantoprazole, Protonix, Zantac, Indigestion, Ranitidine, Dexilant, Lansoprazole, Prevacid, Pepcid, Aciphex, Duodenitis/Gastritis, Famotidine, Heartburn Relief, Rabeprazole, Esomeprazole, Zantac 150

Could Common Heartburn Drugs Up Stroke Risk?

Posted 15 Nov 2016 by Drugs.com

TUESDAY, Nov. 15, 2016 – A popular category of heartburn medications – including Nexium, Prevacid, Prilosec and Protonix – may increase your risk of stroke, a new study suggests. Known as proton pump inhibitors (PPIs), these drugs increased people's overall stroke risk by 21 percent, said study lead author Dr. Thomas Sehested. However, the risk appears to be driven by people who take high doses, added Sehested, research director at the Danish Heart Foundation in Copenhagen. "People treated with a low dose of PPIs did not have a high risk of stroke," he said. "Those treated with the highest doses of PPIs had the highest risk of stroke." The extent of risk also depends on the specific PPI taken. At the highest dose, stroke risk ranged from 30 percent for lansoprazole (Prevacid) to 94 percent for pantoprazole (Protonix), the researchers said. Takeda Pharmaceutical, the maker of ... Read more

Related support groups: GERD, Heart Disease, Ischemic Stroke, Omeprazole, Nexium, Dementia, Prilosec, Pantoprazole, Zantac, Protonix, Indigestion, Alzheimer's Disease, Ranitidine, Transient Ischemic Attack, Dexilant, Lansoprazole, Prevacid, Pepcid, Barrett's Esophagus, Aciphex

Health Tip: Is it Indigestion?

Posted 6 Jun 2016 by Drugs.com

-- If you've eaten too much or indulged in a food that's greasy, fatty or spicy, you may have an uncomfortable feeling known as indigestion. Here are common symptoms, courtesy of the Cleveland Clinic: A burning sensation in the stomach or upper abdomen. An acidic taste in the mouth. Pain in the abdomen. Occasional diarrhea. Bloatedness or gassiness. Vomiting or nausea. Growling stomach. Read more

Related support groups: GERD, Omeprazole, Nexium, Prilosec, Pantoprazole, Protonix, Zantac, Indigestion, Ranitidine, Dexilant, Lansoprazole, Prevacid, Pepcid, Tums, Milk of Magnesia, Aciphex, Caltrate, Duodenitis/Gastritis, Famotidine, Heartburn Relief

1 in 4 Hospitalized Newborns Gets Heartburn Drugs, Despite Risks

Posted 27 Apr 2016 by Drugs.com

WEDNESDAY, April 27, 2016 – Despite reported risks, nearly one in four infants in neonatal intensive care units (NICUs) are given stomach acid-suppressing drugs, researchers report. However, they noted that the use of these medications has started to decline some in recent years. A number of studies have linked the use of stomach acid-suppressing drugs in hospitalized high-risk infants with infections, necrotizing enterocolitis (a serious disease where intestinal tissue begins to die off) and increased risk of death, the researchers said. These drugs include histamine-2 receptor antagonists such as ranitidine (Zantac), and proton pump inhibitors such as esomeprazole (Nexium). Researchers at Nationwide Children's Hospital in Columbus, Ohio, analyzed data from 43 children's hospitals across the United States from 2006 to 2013. They found that nearly 24 percent of roughly 122,000 newborns ... Read more

Related support groups: Omeprazole, Nexium, Prilosec, Pantoprazole, Zantac, Protonix, Ranitidine, Dexilant, Lansoprazole, Prevacid, Pepcid, Delivery, Aciphex, Famotidine, Heartburn Relief, Rabeprazole, Esomeprazole, Zantac 150, Zegerid, Vimovo

Antacids May Improve Head and Neck Cancer Survival

Posted 2 Dec 2014 by Drugs.com

TUESDAY, Dec. 2, 2014 – Using antacids to control acid reflux may improve head and neck cancer patients' chances of survival, a new study suggests. The researchers examined the effects that two types of antacids – proton pump inhibitors and histamine 2 blockers – had on head and neck cancer patients. More than two-thirds of the nearly 600 patients in the study took one or both types of the antacids after their cancer diagnosis. Acid reflux – commonly known as heartburn – is a common side effect of chemotherapy or radiation treatment, according to the researchers. Proton pump inhibitors include drugs such as Prilosec, Nexium and Prevacid, while histamine 2 blockers include drugs such as Tagamet, Zantac and Pepcid. Compared to patients who didn't take antacids, those who took proton pump inhibitors had a 45 percent lower risk of death, according to the researchers. They also found ... Read more

Related support groups: Omeprazole, Nexium, Prilosec, Pantoprazole, Protonix, Zantac, Ranitidine, Dexilant, Lansoprazole, Prevacid, Pepcid, Aciphex, Famotidine, Heartburn Relief, Rabeprazole, Esomeprazole, Zantac 150, Zegerid, Pepcid AC, Pepcid Complete

Health Tip: When Food and Drugs Interact

Posted 27 Feb 2014 by Drugs.com

-- When food and drinks interact with medication, the medication may not work sufficiently or the drug can become too powerful as the body has trouble handling it properly. The Academy of Nutrition and Dietetics mentions these common examples of food and drug interaction: Grapefruit juice interacts with several drugs and may affect the way the body metabolizes medication. Drugs that may interact with grapefruit juice include: some statins, antihistamines, thyroid medications, blood pressure medications, birth control pills, cough suppressants and medications that block stomach acids. Blood-thinning medications can interact with leafy green vegetables, affecting the blood's clotting ability. Natural black licorice may interact with certain blood pressure medications and blood-thinning medications. Salt substitutes can interact with ACE inhibitors and digoxin. Tyramine (found in foods ... Read more

Related support groups: Plan B, Hydrocodone, Mirena, Nexplanon, Depo-Provera, Provera, NuvaRing, Sprintec, Implanon, Codeine, Ortho Tri-Cyclen, Tri-Sprintec, Microgestin Fe 1/20, Yasmin, Amlodipine, Plan B One-Step, Loestrin 24 Fe, Ortho Evra, TriNessa, Lutera

Acid-Reflux Drugs Tied to Lower Levels of Vitamin B-12

Posted 10 Dec 2013 by Drugs.com

TUESDAY, Dec. 10, 2013 – People who take certain acid-reflux medications might have an increased risk of vitamin B-12 deficiency, according to new research. Taking proton pump inhibitors (PPIs) to ease the symptoms of excess stomach acid for more than two years was linked to a 65 percent increase in the risk of vitamin B-12 deficiency. Commonly used PPI brands include Prilosec, Nexium and Prevacid. Researchers also found that using acid-suppressing drugs called histamine-2 receptor antagonists – also known as H2 blockers – for two years was associated with a 25 percent increase in the risk of B-12 deficiency. Common brands include Tagamet, Pepcid and Zantac. "This study raises the question of whether or not people who are on long-term acid suppression need to be tested for vitamin B-12 deficiency," said study author Dr. Douglas Corley, a research scientist and gastroenterologist at ... Read more

Related support groups: GERD, Omeprazole, Nexium, Prilosec, Pantoprazole, Protonix, Zantac, Ranitidine, Dexilant, Lansoprazole, Prevacid, Pepcid, Aciphex, Famotidine, Vitamin B12 Deficiency, Heartburn Relief, Rabeprazole, Esomeprazole, Zantac 150, Zegerid

Antihistamine Meds May Raise Risk for Diarrheal Illness

Posted 29 Mar 2013 by Drugs.com

FRIDAY, March 29 – Patients who take antihistamines to reduce stomach acid are at increased risk for infection with Clostridium difficile, a common cause of diarrhea, a new study finds. Researchers reviewed the findings of 33 previous studies that looked at C. difficile and antihistamines used to suppress stomach acid. People who took over-the-counter antihistamine drugs did not have a significantly increased risk of C. difficile infection. However, a clear link existed between histamine 2 receptor antagonists – a specific class of antihistamines – and C. difficile infection. The risk for people on these drugs – also known as H2 blockers – was greatest for hospitalized patients receiving antibiotics, said the researchers from the Mayo Clinic in Rochester, Minn. The study was published online March 27 in the journal PLoS One. "It's not clear why these antihistamines increase the ... Read more

Related support groups: Zantac, Ranitidine, Pepcid, Famotidine, Heartburn Relief, Zantac 150, Pepcid AC, Clostridial Infection, Pepcid Complete, Tagamet, Zantac 75, Cimetidine, Axid, Nizatidine, Axid AR, Tagamet HB, Zantac 150 EFFERdose, Ranitidine Bismuth Citrate, Zantac 25 mg EFFERdose, Pepcid RPD

Which Hospital Patients Need Drugs to Prevent Gastrointestinal Bleeding?

Posted 10 Jan 2013 by Drugs.com

THURSDAY, Jan. 10 – Researchers have developed a scoring system to help doctors determine which hospital patients can be prescribed stomach acid-suppressing drugs to prevent gastrointestinal bleeding and which patients should not be given such medications. Gastrointestinal bleeding in hospital patients is rare, but it is dangerous and potentially fatal, according to the study authors. Although the use of acid suppressants to prevent gastrointestinal bleeding in patients who are not critically ill is not widely recommended, the medications are commonly used for this purpose, said Shoshana Herzig and colleagues at the Beth Israel Deaconess Medical Center in Boston. The study was published online recently in the Journal of General Internal Medicine. The researchers analyzed data from more than 75,000 hospital patients admitted over three years and found that gastrointestinal bleeding ... Read more

Related support groups: Omeprazole, Nexium, Prilosec, Pantoprazole, Protonix, Zantac, Ranitidine, Dexilant, Lansoprazole, Prevacid, Pepcid, Aciphex, Famotidine, Heartburn Relief, Rabeprazole, Esomeprazole, Zantac 150, Zegerid, Pepcid AC, Pepcid Complete

No One Treatment for Acid Reflux Clearly Better Than Another: Study

Posted 29 Sep 2011 by Drugs.com

THURSDAY, Sept. 29 – Medications are effective for most patients with acid reflux disease, but some surgical options may be just as effective, according to a review of studies on current treatments for this common condition. Acid reflux disease, also known as gastroesophageal reflux disease or GERD, occurs when the contents of the stomach – including burning acid – chronically spill up into the esophagus, causing heartburn and other symptoms such as a persistent cough, laryngitis and asthma. Acid reflux disease may afflict as many as 4 percent of Americans, resulting not only in a sometimes significant financial drain but also more serious long-term consequences such as esophageal cancer, according to background information in the report released Sept. 23 by the U.S. Agency for Healthcare Research & Quality (AHRQ), part of the U.S. Department of Health & Human Services. Obesity, ... Read more

Related support groups: GERD, Omeprazole, Nexium, Prilosec, Pantoprazole, Protonix, Zantac, Ranitidine, Dexilant, Lansoprazole, Prevacid, Pepcid, Aciphex, Famotidine, Heartburn Relief, Rabeprazole, Esomeprazole, Zantac 150, Zegerid, Pepcid AC

Heartburn Drugs May Raise Pneumonia Risk

Posted 21 Dec 2010 by Drugs.com

MONDAY, Dec. 20 – Popular heartburn drugs, including proton pump inhibitors and histamine-2 receptor antagonists, may raise the risk of pneumonia, new research finds. Researchers in Korea analyzed the results of 31 studies on heartburn drugs published between 1985 and 2009. "Our results suggest that the use of acid suppressive drugs is associated with an increased risk of pneumonia," said Dr. Sang Min Park of the department of family medicine at Seoul National University Hospital in Korea. "Patients should be cautious at overuse of acid-suppressive drugs, both high-dose and long duration," he added. Sales of these enormously popular drugs – the second best-selling category of medications worldwide – reached nearly $27 billion in the United States in 2005, according to background information in the study, published Dec. 20 in CMAJ (Canadian Medical Association Journal). Proton pump ... Read more

Related support groups: GERD, Omeprazole, Nexium, Prilosec, Pantoprazole, Zantac, Protonix, Ranitidine, Dexilant, Lansoprazole, Prevacid, Pepcid, Aciphex, Famotidine, Heartburn Relief, Rabeprazole, Esomeprazole, Zantac 150, Zegerid, Vimovo

Right Match of Drug, Doctor Can Boost Reflux Outcomes

Posted 12 Jan 2010 by Drugs.com

FRIDAY, Aug. 21 – Chronic heartburn caused by acid reflux is one of the most common complaints among Americans, and a new study outlines which approaches appear to work best to ease patients' suffering. The Danish study found that people with the condition – formally called gastroesophageal reflux disease (GERD) – typically feel best when placed on medications called proton pump inhibitors (PPIs) by a doctor with whom they have a good rapport. "The treatment we have isn't always perfect," conceded Dr. Maria T. Abreu, professor of medicine and chief of the division of gastroenterology at the University of Miami Miller School of Medicine, who was not involved in the study. She agreed that communicating well with patients can go a long way toward increasing their satisfaction, because reflux treatments don't always relieve all symptoms. If doctors said that up front, patients "might be ... Read more

Related support groups: GERD, Omeprazole, Nexium, Prilosec, Pantoprazole, Zantac, Protonix, Ranitidine, Lansoprazole, Prevacid, Pepcid, Aciphex, Famotidine, Heartburn Relief, Rabeprazole, Esomeprazole, Zantac 150, Zegerid, Pepcid AC, Pepcid Complete

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GERD, Erosive Esophagitis, Indigestion, Stomach Ulcer, Gastric Ulcer, Duodenal Ulcer Prophylaxis, Duodenal Ulcer

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