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Doctors Seeing More HIV Patients With Multidrug Resistance

Posted 2 days 15 hours ago by Drugs.com

THURSDAY, Dec. 1, 2016 – A significant number of people with HIV have strains of the AIDS-causing virus that are resistant to both older and newer drugs, researchers report. The researchers looked at 712 HIV patients worldwide whose infection was not controlled by antiretroviral drugs. They found that 16 percent of patients whose infection was resistant to modern drugs had HIV mutations linked with resistance to older drugs called thymidine analogues. Among patients whose HIV had this mutation, 80 percent were also resistant to tenofovir, the main drug in most modern HIV treatment and prevention programs, the researchers reported. The findings were published in the Nov. 30 issue of The Lancet Infectious Diseases journal. "We were very surprised to see that so many people were resistant to both drugs, as we didn't think this was possible," study lead author Ravi Gupta, of University ... Read more

Related support groups: Harvoni, HIV Infection, Atripla, Sovaldi, Pre-Exposure Prophylaxis, Incivek, Truvada, Stribild, Complera, Triumeq, Baraclude, Victrelis, Sofosbuvir, Genvoya, Zepatier, Viread, Epclusa, Kaletra, Viekira Pak, Norvir

HIV Infection Seems to Affect Nervous System

Posted 13 Jun 2016 by Drugs.com

MONDAY, June 13, 2016 – Many newly infected HIV patients experience neurological problems, but they tend to be mild and they subside after antiretroviral drugs are given, a new study finds. "We were surprised that neurologic findings were so pervasive in participants diagnosed with very recent HIV infection," said study author Dr. Joanna Hellmuth. She is a clinical fellow in the department of neurology at the University of California, San Francisco (UCSF). "While the findings were mild, it is clear that HIV affects the nervous system within days of infection," she said in a university news release. "Since the majority of these neurologic issues were resolved with treatment, our study reinforces recommendations that people at risk for HIV test often and start antiretroviral treatment immediately if they are infected," Hellmuth added. Among 139 people in Thailand infected with HIV three ... Read more

Related support groups: Peripheral Neuropathy, Harvoni, HIV Infection, Atripla, Pre-Exposure Prophylaxis, Incivek, Truvada, Stribild, Complera, Triumeq, Autonomic Neuropathy, Baraclude, Victrelis, Genvoya, Zepatier, Viread, Viekira Pak, Kaletra, Norvir, Daklinza

HIV Decline Falls Short of U.S. 5-Year Goal

Posted 6 May 2016 by Drugs.com

FRIDAY, May 6, 2016 – Although HIV infection and transmission rates in the United States declined over the past five years, they fell short of White House targets, a new study finds. Between 2010 and 2015, new HIV infections decreased 11 percent and transmission of the AIDS-causing virus declined 17 percent, far less than the goals set in 2010 as part of the U.S. National HIV/AIDS Strategy (NHAS), researchers said. The NHAS goals for 2015 were reductions of 25 percent for new HIV infections and 30 percent declines in HIV transmission. "Even though we missed the goals by a sizable margin, it's promising to see that we made important progress in reducing rates of HIV infection and transmission," said lead study author Robert Bonacci. He is a fourth-year medical student at the University of Pennsylvania Perelman School of Medicine. The aim was to lower the persistent HIV infection rate ... Read more

Related support groups: Harvoni, HIV Infection, Atripla, Pre-Exposure Prophylaxis, Incivek, Truvada, Stribild, Triumeq, Complera, Baraclude, Victrelis, Genvoya, Zepatier, Viread, Viekira Pak, Kaletra, Norvir, Entecavir, Tenofovir, Telaprevir

Prenatal Use of HIV Drug May Slow Child's Development Slightly

Posted 23 Feb 2016 by Drugs.com

TUESDAY, Feb. 23, 2016 – A drug used to prevent mother-to-child HIV transmission during pregnancy may slow language development slightly in children, a new study suggests. Researchers followed more than 900 infants who were born to HIV-positive mothers but were not infected by the AIDS-causing virus. All of the mothers took antiretroviral drugs during pregnancy. Some of the treatment regimens included a drug called atazanavir (Reyataz), while others did not. The infants underwent a standard test of development at 1 year of age. The 167 infants whose mothers took atazanavir during pregnancy had slightly lower language and social development scores than the 750 infants whose mothers did not take the drug. But the study only showed an association between atazanavir and language delays in children, and did not prove a cause-and-effect link. And the difference in social development scores ... Read more

Related support groups: Harvoni, HIV Infection, Atripla, Pre-Exposure Prophylaxis, Incivek, Truvada, Stribild, Triumeq, Complera, Baraclude, Victrelis, Genvoya, Viread, Viekira Pak, Kaletra, Norvir, Entecavir, Tenofovir, Telaprevir, Lamivudine

Vaginal Ring Offers Some Protection Against HIV, Study Says

Posted 23 Feb 2016 by Drugs.com

MONDAY, Feb. 22, 2016 – An insertable vaginal ring containing a month's supply of a continuous-release HIV prevention drug reduced the risk of HIV in African women by at least 27 percent, a new study found. The ring works by slowly and continuously delivering a highly localized and controlled amount of the antiretroviral medication dapivirine. This drug aims to halt the ability of HIV – the virus that causes AIDS – to replicate inside a healthy cell. The goal: to prevent HIV infection, rather than treat it, the researchers said. "These results come after a number of challenging years in the effort to find ways to improve HIV control," said study lead author Dr. Jared Baeten, a professor in the departments of global health, medicine and epidemiology at the University of Washington in Seattle. "But while the dapivirine vaginal ring isn't commercially available yet, I'm really very ... Read more

Related support groups: Harvoni, HIV Infection, Atripla, Pre-Exposure Prophylaxis, Incivek, Truvada, Stribild, Triumeq, Complera, Baraclude, Viral Infection, Victrelis, Genvoya, Viread, Kaletra, Viekira Pak, Norvir, Tenofovir, Entecavir, Telaprevir

CDC: Black Americans With HIV Still Less Likely to Get Ongoing Medical Care

Posted 5 Feb 2016 by Drugs.com

FRIDAY, Feb. 5, 2016 – While HIV diagnoses dropped significantly over the past decade in the United States, blacks with HIV are less likely than whites or Hispanics to receive routine, ongoing care, according to the U.S. Centers for Disease Control and Prevention. From 2005 to 2014, annual HIV diagnoses fell 19 percent in the United States. Infections among black women dropped 42 percent during this period. Despite this progress in the fight against HIV, racial disparities persist, the CDC found. While black people make up 12 percent of the U.S. population, they accounted for nearly half of all HIV diagnoses in 2014. "CDC has been working for many years to eliminate the HIV disparities that exist within the black community," Dr. Eugene McCray, director of the CDC's Division of HIV/AIDS Prevention, said in an agency news release. "While we are seeing signs of success, we must continue ... Read more

Related support groups: Harvoni, HIV Infection, Atripla, Tamiflu, Pre-Exposure Prophylaxis, Incivek, Truvada, Stribild, Complera, Triumeq, Baraclude, Victrelis, Genvoya, Viread, Oseltamivir, Viekira Pak, Kaletra, Norvir, Entecavir, Tenofovir

Resistance to HIV Drug Growing, Study Finds

Posted 29 Jan 2016 by Drugs.com

FRIDAY, Jan. 29, 2016 – HIV resistance to the antiretroviral drug tenofovir (Viread) is increasingly common, a new study finds. The researchers said their finding is surprising and alarming because the drug plays a major role in treating and preventing infection with HIV, the virus that causes AIDS. "Tenofovir is a critical part of our armamentarium against HIV, so it is extremely concerning to see such a high level of resistance to this drug," study author Dr. Ravi Gupta, from the department of infection and immunity at University College London in England, said in a university news release. "It is very potent drug with few side effects, and there aren't any good alternatives that can be deployed using a public health approach. Tenofovir is used not only to treat HIV but also to prevent it in high-risk groups, so we urgently need to do more to combat the problem of emerging ... Read more

Related support groups: HIV Infection, Atripla, Pre-Exposure Prophylaxis, Truvada, Stribild, Complera, Viral Infection, Genvoya, Viread, Tenofovir, Emtricitabine/rilpivirine/tenofovir, Cobicistat/elvitegravir/emtricitabine/tenofovir, Efavirenz/Emtricitabine/Tenofovir, Emtricitabine/nelfinavir/tenofovir, Emtricitabine/Tenofovir, Emtricitabine/lopinavir/ritonavir/tenofovir

HIV Can Persist in Body Despite Drug Therapy

Posted 27 Jan 2016 by Drugs.com

WEDNESDAY, Jan. 27, 2016 – Even when blood tests of HIV patients on antiretroviral drugs show no sign of the AIDS-causing virus, it can still be replicating in lymphoid tissue, researchers report. The study offers important new insight into how HIV persists in the body despite treatment with the powerful drugs, according to the team of international researchers led by Northwestern University's Feinberg School of Medicine in Chicago. To reach their finding, they examined viral sequences in samples of lymph node and blood cells from three HIV-infected patients who had no detectable virus in their blood. And what they found was that a viral reservoir in lymphoid tissue, which scientists believed held long-lived infected cells in a resting state, was being constantly replenished with infected cells. "The challenge is to deliver drugs at clinically effective concentrations to where the ... Read more

Related support groups: Harvoni, HIV Infection, Atripla, Sovaldi, Pre-Exposure Prophylaxis, Incivek, Truvada, Stribild, Complera, Triumeq, Baraclude, Victrelis, Sofosbuvir, Genvoya, Viread, Kaletra, Viekira Pak, Diagnosis and Investigation, Norvir, Daklinza

FDA Lifts Ban on Blood Donations by Gay Men

Posted 21 Dec 2015 by Drugs.com

MONDAY, Dec. 21, 2015 – Gay and bisexual men who have abstained from sex for one year will now be allowed to donate blood in the United States. The new policy, announced Monday by the U.S. Food and Drug Administration, reverses a three-decades-old ban on donations from this group of men that traces back to the start of the AIDS epidemic. "The FDA's responsibility is to maintain a high level of blood product safety for people whose lives depend on it," FDA Acting Commissioner Stephen Ostroff said in an agency news release. "We have taken great care to ensure this policy revision is backed by sound science and continues to protect our blood supply." The FDA said it was changing its policy based on data from other countries that show allowing such donations would not increase the risk of HIV-tainted blood entering America's blood supply. FDA officials have estimated that about half of the ... Read more

Related support groups: Blood Disorders, Bleeding Disorder, Harvoni, HIV Infection, Valtrex, Anemia, Acyclovir, Atripla, Tamiflu, Ribavirin, Valacyclovir, Pre-Exposure Prophylaxis, Incivek, Blood Transfusion, Zovirax, Truvada, Stribild, Triumeq, Complera, Baraclude

Risky Sexual Behaviors Put Many Young Gay Men at Risk of HIV: Study

Posted 7 Dec 2015 by Drugs.com

MONDAY, Dec. 7, 2015 – Young American gay and bisexual men who have detectable blood levels of HIV – the virus that causes AIDS – are also more likely to engage in risky sexual behavior that might spread the virus, a new study has found. "While many of these young men are engaged in care, and success stories are many, we still have work to do to reduce the rate of new infections," study author Patrick Wilson, an assistant professor of sociomedical sciences at Columbia University's Mailman School of Public Health in New York City, said in a university news release. Different strategies to help prevent HIV infections and promote safe sex are needed for this group, his team wrote in the Dec. 7 issue of the journal JAMA Pediatrics. According to the researchers, young men between the ages of 13 and 29 who are gay or bisexual are particularly vulnerable to infection with HIV and now ... Read more

Related support groups: Birth Control, Contraception, Emergency Contraception, Harvoni, HIV Infection, Postcoital Contraception, Atripla, Pre-Exposure Prophylaxis, Incivek, Truvada, Stribild, Complera, Triumeq, Baraclude, Victrelis, Viread, Viekira Pak, Kaletra, Norvir, Entecavir

HIV Rates Fall, But Not All Groups Benefit, U.S. Study Finds

Posted 7 Dec 2015 by Drugs.com

MONDAY, Dec. 7, 2015 – The number of Americans diagnosed with HIV each year declined by about one-fifth during the past decade, but not all groups saw drops in prevalence, a federal government study shows. Between 2005 and 2014, the overall annual number of HIV diagnoses fell 19 percent – from nearly 48,800 to just over 39,700 a year. The drop was led by a 63 percent decline among injection drug users, a 42 percent drop among black women, and a 35 percent decrease among heterosexuals. However, annual HIV diagnoses among gay and bisexual men actually rose about 6 percent during the study period, from about 25,000 to just over 26,600 a year, although they recently stabilized at less than a 1 percent increase a year. The increase in HIV diagnoses among gay and bisexual men was driven largely by blacks and Hispanics, the U.S. Centers for Disease Control and Prevention report found. HIV ... Read more

Related support groups: Harvoni, HIV Infection, Atripla, Incivek, Truvada, Stribild, Triumeq, Complera, Baraclude, Victrelis, Viread, Viekira Pak, Kaletra, Norvir, Tenofovir, Entecavir, Diagnosis and Investigation, Telaprevir, Ledipasvir/sofosbuvir, Prezista

Preventive HIV Treatment Shown Effective at Health Clinics

Posted 16 Nov 2015 by Drugs.com

MONDAY, Nov. 16, 2015 – Medications taken to prevent HIV infection in high-risk people appear to work well in "real-life" use, a new study suggests. During a year of taking pre-exposure prophylaxis (PrEP), only two people out of more than 400 high-risk people became infected with HIV, the virus that causes AIDS. And it seems that those who became infected didn't take the medication properly, the study said. The new study found the HIV infection rate was as much as 20 times lower than in several previous HIV studies, background information in the current study said. Gay and bisexual men at high risk for HIV infection "should be counseled about pre-exposure prophylaxis," said Dr. Kenneth Mayer, director of HIV Prevention Research at Beth Israel Deaconess Medical Center in Boston, who's familiar with the study findings. Already, he said, "pharmacy records suggest that tens of thousands ... Read more

Related support groups: HIV Infection, Atripla, Pre-Exposure Prophylaxis, Truvada, Stribild, Complera, Viread, Tenofovir, Emtricitabine/rilpivirine/tenofovir, Cobicistat/elvitegravir/emtricitabine/tenofovir, Efavirenz/Emtricitabine/Tenofovir, Emtricitabine/nelfinavir/tenofovir, Emtricitabine/Tenofovir, Emtricitabine/lopinavir/ritonavir/tenofovir

HIV Therapy May Also Lower Risk for Hepatitis B, Study Says

Posted 12 Oct 2015 by Drugs.com

MONDAY, Oct. 12, 2015 – Not only does effective HIV therapy thwart the AIDS-causing virus, it may also reduce the risk for hepatitis B infection, a new study says. "What this means to us is that effective HIV therapy appears to restore an impairment in the immune response that protects someone with HIV from acquiring hepatitis B infection," study senior author Dr. Chloe Thio, a professor of medicine at Johns Hopkins University School of Medicine, said in a university news release. The study, published in the October issue of Annals of Internal Medicine, involved 2,400 gay and bisexual men who were enrolled in the Multicenter AIDS Cohort Study. Researchers found that the men successfully treated with HIV therapy had the same risk for hepatitis B infection as the men who did not have HIV. Hepatitis B is a virus that can damage the liver. The study showed HIV-positive men on HIV therapy ... Read more

Related support groups: Harvoni, HIV Infection, Valtrex, Acyclovir, Atripla, Hepatitis B, Sovaldi, Ribavirin, Valacyclovir, Pre-Exposure Prophylaxis, Incivek, Zovirax, Truvada, Pegasys, Stribild, Complera, Triumeq, Baraclude, Victrelis, Famciclovir

Many U.S. AIDS Patients Still Die When 'Opportunistic' Infections Strike

Posted 1 Jul 2015 by Drugs.com

WEDNESDAY, July 1, 2015 – Even after the advent of powerful medications for suppressing HIV, a new study finds that more than one-third of people in San Francisco who were diagnosed with an AIDS-related infection died within five years. "The main cause of mortality arises from people stopping treatment entirely," said Dr. Robert Grant, a professor at the University of California, San Francisco, who reviewed the findings but was not involved in the research. When HIV treatment lapses, so-called "opportunistic" infections and illnesses can arise, posing a real threat to patients' health, he explained. The bottom line, according to Grant, is that there is still "a long way to go" in prolonging the lives of Americans with HIV/AIDS. The new study was led by Dr. Sandra Schwarcz, associate professor of epidemiology and biostatistics at the University of California, San Francisco. She and her ... Read more

Related support groups: Harvoni, HIV Infection, Atripla, Tamiflu, Sovaldi, Pre-Exposure Prophylaxis, Incivek, Truvada, Stribild, Triumeq, Complera, Baraclude, Victrelis, Sofosbuvir, Mycobacterium avium-intracellulare, Mycobacterium avium-intracellulare - Treatment, Oseltamivir, Viread, Kaletra, Norvir

Sequence of Shots May Lead to Effective HIV Vaccine, Mouse Study Finds

Posted 25 Jun 2015 by Drugs.com

THURSDAY, June 25, 2015 – It's unlikely that a single vaccine would ever enable the body to neutralize the HIV virus, but a sequence of immunizations might hold the key, a new mouse study suggests. The immune system could be guided in a series of steps to develop a special type of HIV-fighting antibody, a team of researchers said. Each immunization would be customized for specific stages of the immune system's response to the virus. In the end, the series of shots would result in the production of broadly neutralizing antibodies capable of fighting HIV, the authors said. "As HIV mutates in a patient, the immune system continually adapts. In some patients, this process produces broadly neutralizing antibodies, which are unusual antibodies that can bind to and neutralize a wide range of globally occurring HIV variants. These are the antibodies we want to try to elicit with a vaccine," ... Read more

Related support groups: Harvoni, HIV Infection, Atripla, Sovaldi, Pre-Exposure Prophylaxis, Incivek, Truvada, Stribild, Triumeq, Complera, Baraclude, Victrelis, Sofosbuvir, Viread, Kaletra, Entecavir, Norvir, Tenofovir, Telaprevir, Nevirapine

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