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Pradaxa Blood Thinner May Beat Warfarin After Bleeding Episode: Study

Posted 2 days 7 hours ago by Drugs.com

THURSDAY, Dec. 1, 2016 – Use of a blood thinner is routine for many heart patients, but these drugs come with a risk of episodes of excess bleeding. What, if any, anticoagulant (blood thinner) should these patients take after such episodes arise? A new study suggests that the blood thinner Pradaxa (dabigatran) may be a better choice than the standby drug warfarin in these cases. The reason: Pradaxa is less likely than warfarin to cause recurrent bleeding in patients who recently suffered a bleeding stroke or other major bleeding event, the researchers found. "Our results should encourage clinicians to seriously consider resuming anticoagulation among patients who survived a major bleeding event, particularly if the source of bleeding was identified and addressed," said study senior author Dr. Samir Saba. He's associate chief of cardiology at the University of Pittsburgh Heart and ... Read more

Related support groups: Bleeding Disorder, Warfarin, Coumadin, Ischemic Stroke, Xarelto, Pradaxa, Lovenox, Eliquis, Transient Ischemic Attack, Heparin, Rivaroxaban, Ischemic Stroke - Prophylaxis, Enoxaparin, Apixaban, Fragmin, Clexane, Arixtra, Hep-Pak, Intracranial Hemorrhage, Jantoven

Many Atrial Fibrillation Patients Missing Out on Blood Thinners

Posted 17 days ago by Drugs.com

WEDNESDAY, Nov. 16, 2016 – Half of patients hospitalized with the heart rhythm disorder atrial fibrillation aren't given blood-thinning drugs that reduce the risk of clots and stroke, a new study finds. Atrial fibrillation, a type of irregular heartbeat, puts people at higher risk for blood clots and stroke, researchers from Duke University said. They analyzed nearly 1.6 million admissions for atrial fibrillation at 812 hospitals across the United States over five years and found that only 46 percent of patients received blood thinners at discharge. "This low rate of [blood thinner] use in hospitalized patients highlights an important opportunity to improve care in atrial fibrillation patients," said study co-author Dr. Sean Pokorney, an electrophysiology fellow at Duke School of Medicine in Durham, N.C. The patients in the study were 40 and older, stayed in the hospital for at least ... Read more

Related support groups: Blood Disorders, Warfarin, Coumadin, Atrial Fibrillation, Xarelto, Eliquis, Prevention of Thromboembolism in Atrial Fibrillation, Rivaroxaban, Apixaban, Arixtra, Fondaparinux, Jantoven, Savaysa, Edoxaban, Anisindione, Arixtra 10 mg/dose, Arixtra 7.5 mg/dose, Dicumarol, Arixtra 5 mg/dose, Miradon

Gene Test May ID Chemo Patients at Risk of Clots: Study

Posted 1 Nov 2016 by Drugs.com

TUESDAY, Nov. 1, 2016 – Genetic testing could help identify breast cancer patients at high risk for the formation of blood clots in their veins, new research suggests. This problem, called venous thromboembolism (VTE), is a serious and potentially fatal complication that can occur during cancer treatment, particularly chemotherapy. Because breast cancer is one of the most common cancers, breast cancer patients account for a large number of cancer-related VTE cases, said study author Judith Brand. She's a postdoctoral researcher in the department of medical epidemiology and biostatistics at Karolinska Institute in Stockholm, Sweden. Venous thromboembolism is preventable through treatment with an anti-clotting drug. But side effects, such as bleeding, mean this therapy is not routinely used in patients undergoing chemotherapy, the researchers explained. The new study included more than ... Read more

Related support groups: Blood Disorders, Cancer, Warfarin, Coumadin, Breast Cancer, Xarelto, Prostate Cancer, Pradaxa, Lovenox, Eliquis, Lung Cancer, Colorectal Cancer, Heparin, Melanoma, Rivaroxaban, Enoxaparin, Fragmin, Apixaban, Clexane, Arixtra

Irregular Heart Rhythm Patients May Not Always Need Blood Thinners: Study

Posted 18 Oct 2016 by Drugs.com

TUESDAY, Oct. 18, 2016 – People with an abnormal heart rhythm called atrial fibrillation typically take powerful blood thinners to prevent strokes. But, some patients who have implanted pacemakers or defibrillators may not always need the drugs, a new study suggests. Those who suffered only short bouts of atrial fibrillation – estimated at 20 seconds or less – were at no more risk for stroke or other heart complications than people without atrial fibrillation, the researchers found. "Some patients have atrial fibrillation 100 percent of the time, while others might have only a few seconds of atrial fibrillation once a year," explained study author Dr. Steven Swiryn. He's a clinical professor of cardiology at the Feinberg School of Medicine at Northwestern University in Chicago. "Where atrial fibrillation only happens rarely and lasts a short time, it can be difficult to detect," ... Read more

Related support groups: Warfarin, Coumadin, Atrial Fibrillation, Ischemic Stroke, Xarelto, Eliquis, Transient Ischemic Attack, Prevention of Thromboembolism in Atrial Fibrillation, Rivaroxaban, Ischemic Stroke - Prophylaxis, Apixaban, Thromboembolic Stroke Prophylaxis, Arixtra, Jantoven, Fondaparinux, Coagulation Defects and Disorders, Savaysa, Edoxaban, Arixtra 10 mg/dose, Arixtra 7.5 mg/dose

Irregular Heartbeat May Be Deadly in Car Crash

Posted 10 Jun 2016 by Drugs.com

FRIDAY, June 10, 2016 – Having the common heart rhythm disorder atrial fibrillation might be risky if you get into a car accident, a new study suggests. Atrial fibrillation is a quivering or irregular heartbeat. Researchers report the condition is linked to higher chances of dying if you're in a crash, although their study didn't prove a cause-and-effect relationship. "Atrial fibrillation is the most common heart rhythm disorder, and incidence is rising. Many of these patients are on anticoagulants to lower their stroke risk, but these drugs increase the chance of bleeding," said study author Dr. Abhishek Deshmukh, a cardiologist at the Mayo Clinic in Rochester, Minn. However, "we should not jump the gun and advise patients with atrial fibrillation to stop driving. This was a retrospective observational study and needs to be confirmed by further research," he said in an European ... Read more

Related support groups: Warfarin, Coumadin, Atrial Fibrillation, Xarelto, Pradaxa, Eliquis, Prevention of Thromboembolism in Atrial Fibrillation, Rivaroxaban, Apixaban, Arixtra, Jantoven, Fondaparinux, Dabigatran, Savaysa, Edoxaban, Angiomax, Refludan, Arixtra 10 mg/dose, Anisindione, Arixtra 7.5 mg/dose

Women Less Likely to Get Blood Thinner for Irregular Heartbeat

Posted 8 Jun 2016 by Drugs.com

WEDNESDAY, June 8, 2016 – Among people with the common heart rhythm disorder known as atrial fibrillation, women are less likely than men to receive blood-thinning drugs, a new study reveals. Blood thinners are important for people with atrial fibrillation because they help prevent stroke. Atrial fibrillation causes an irregular heartbeat. In people with atrial fibrillation, blood doesn't move from one part of the heart to the other as it should. Instead, the blood can pool and may clot. If a clot travels to the brain, it can cause a stroke. Blood-thinning drugs can help keep clots from forming, according to the U.S. National Heart, Lung, and Blood Institute. For the study, researchers reviewed data from nearly 1,600 people with atrial fibrillation. Among these patients, 55 percent of women were taking blood thinners, compared with 61 percent of men. "The irony is that women have a ... Read more

Related support groups: Warfarin, Coumadin, Atrial Fibrillation, Xarelto, Pradaxa, Eliquis, Prevention of Thromboembolism in Atrial Fibrillation, Rivaroxaban, Apixaban, Arixtra, Fondaparinux, Jantoven, Dabigatran, Edoxaban, Savaysa, Anisindione, Arixtra 10 mg/dose, Arixtra 7.5 mg/dose, Reversal of Dabigatran, Dicumarol

The Pill, Hormone Therapy Safe for Women Taking Blood Thinners: Study

Posted 22 Dec 2015 by Drugs.com

TUESDAY, Dec. 22, 2015 – Women on blood thinners can also take contraceptives that contain estrogen, or hormone replacement therapy, without raising their risk for blood clots or uterine bleeding, a new Italian study finds. Currently, women diagnosed with blood clots may be advised to stop hormone therapy or use of the contraceptive pill – even if they are already on a blood thinner. The reason: Doctors are often concerned that these drug combinations might raise the patient's risk for more clots. However, "there has been no evidence to support this decision," said the study's senior author, Dr. Ida Martinelli, of the A. Bianchi Bonomi Hemophilia and Thrombosis Center in Milan. "We conducted this study to address the fear felt by both the physician and patient when making the decision to stop or continue hormone therapy in this setting," she explained in a news release from the ... Read more

Related support groups: Birth Control, Contraception, Blood Disorders, Emergency Contraception, Bleeding Disorder, Warfarin, Coumadin, Hot Flashes, Estradiol, Menopausal Disorders, Xarelto, Premarin, Pradaxa, Ethinyl Estradiol, Postcoital Contraception, Estrace, Postmenopausal Symptoms, Lovenox, Eliquis, Vagifem

Health Tip: Know Your Risk for Deep Vein Thrombosis

Posted 4 Aug 2015 by Drugs.com

-- A dangerous condition called deep vein thrombosis (DVT) occurs when a blood clot develops in a vein deep inside the body. The U.S. National Heart Lung and Blood Institute mentions these potential risk factors: Having had a previous DVT, or taking medication that thickens the blood or promotes clotting. Having had surgery, a broken bone or other injury that affects a deep vein. Having reduced blood flow to a deep vein as a result of inactivity. Typical causes are post-surgical recovery, or taking a long trip that limits your ability to move around. Being pregnant. Being treated for cancer. Having a central venous catheter. Being over the age of 60, being a smoker or being obese. Read more

Related support groups: Blood Disorders, Warfarin, Coumadin, Xarelto, Deep Vein Thrombosis (DVT), Pradaxa, Lovenox, Eliquis, Deep Vein Thrombosis, Heparin, Deep Vein Thrombosis - First Event, Deep Vein Thrombosis - Recurrent Event, Rivaroxaban, Enoxaparin, Apixaban, Deep Vein Thrombosis Prophylaxis after Knee Replacement Surgery, Fragmin, Clexane, Arixtra, Hep-Pak

How Long Do Patients With Clots in the Lung Need Blood Thinners?

Posted 7 Jul 2015 by Drugs.com

TUESDAY, July 7, 2015 – People who suffer a blood clot in the lungs with no obvious cause can ward off a new clot with extended use of blood-thinning medications, a new study shows. However, the length of time those blood thinners should be given is unclear, since their benefits wear off soon after use is discontinued, the French researchers found. The clots are called pulmonary emboli, explained one U.S. expert, Dr. Richard Hayes. "Pulmonary emboli are clots in the blood vessels to the lungs that arise from the veins of the leg or thigh," said Hayes, a cardiologist at Lenox Health in New York City. One type of clot is deep vein thrombosis (DVT), often nicknamed "economy-class syndrome" because of cases occurring after long-haul flights. In many cases, Hayes said, there's a trigger – extended bedrest, obesity, recent surgery – for the clot, but in other cases the clots seem to arise ... Read more

Related support groups: Warfarin, Coumadin, Xarelto, Pradaxa, Pulmonary Embolism, Lovenox, Eliquis, Heparin, Rivaroxaban, Pulmonary Embolism - Recurrent Event, Enoxaparin, Apixaban, Fragmin, Clexane, Arixtra, Hep-Pak, Jantoven, Dabigatran, Fondaparinux, Dalteparin

White Men May Get Better Treatment for Abnormal Heartbeat

Posted 30 Jun 2015 by Drugs.com

TUESDAY, June 30, 2015 – Women, Hispanics and blacks are less likely than white men to receive optimal treatment for atrial fibrillation in the United States, researchers say. The study of more than a half-million Medicare patients found that women with this abnormal heart rhythm are less likely than men to get blood thinners to prevent stroke, which is a serious risk with atrial fibrillation. Women, blacks and Hispanics are also less likely to get catheter ablation, a surgical procedure that can restore the heart's normal rhythm. "Across the board, women are offered less aggressive care, particularly in cardiology," said lead researcher Dr. Prashant Bhave, a clinical assistant professor of internal medicine at University of Iowa Health Care. "There are still gaps in how patients are treated," he said. "The most important one is the difference in prescribing blood thinners. Ablation ... Read more

Related support groups: Warfarin, Coumadin, Atrial Fibrillation, Xarelto, Pradaxa, Lovenox, Eliquis, Heparin, Prevention of Thromboembolism in Atrial Fibrillation, Rivaroxaban, Enoxaparin, Fragmin, Apixaban, Clexane, Thromboembolic Stroke Prophylaxis, Arixtra, Hep-Pak, Jantoven, Fondaparinux, Dalteparin

Blood Thinners OK for Cancers That Spread to Brain, Study Finds

Posted 2 Jun 2015 by Drugs.com

TUESDAY, June 2, 2015 – Blood-thinning drugs are safe for treating blood clots in patients with cancer that has spread to the brain from other areas of the body, according to new research. Cancer normally increases a person's risk of blood clots, the study authors explained in a news release from the American Society of Hematology. When a cancer patient develops a clot, a blood thinner – also called an anticoagulant – is often added to the cancer treatment regimen to prevent the risk of blood clots traveling to the lungs. Such a clot can be fatal. However, if cancer spreads from other parts of the body to the brain (called brain metastases), doctors are hesitant to prescribe blood thinners because of concern they might cause bleeding in the head, which is already a risk for these patients, the study authors added. The new findings show that the use of blood thinners in these patients ... Read more

Related support groups: Cancer, Warfarin, Coumadin, Xarelto, Pradaxa, Lovenox, Eliquis, Heparin, Brain Tumor, Rivaroxaban, Enoxaparin, Fragmin, Apixaban, Clexane, Arixtra, Hep-Pak, Jantoven, Dabigatran, Fondaparinux, Innohep

Pharmacists Key to Whether Patients Take Blood Thinners

Posted 14 Apr 2015 by Drugs.com

TUESDAY, April 14, 2015 – Millions of older Americans are prescribed a blood thinner to help reduce the stroke risks associated with a dangerous irregular heart beat known as atrial fibrillation. A new study finds that even though a large percentage fail to take the potentially life-saving medications as prescribed, the intervention of their local pharmacist might help. In the study, a team led by Dr. Mintu Turakhia, an assistant professor of medicine at Stanford University, in Palo Alto, Calif., looked at the use of the blood thinner Pradaxa (dabigatran) by Veterans Administration outpatients who were prescribed the drug between 2010 and 2012. Pradaxa belongs to a new class of twice-daily oral blood thinners, and it is often prescribed for atrial fibrillation (nicknamed "a-fib"). "The new oral anticoagulants, such as dabigatran, represent the biggest medical change in the delivery of ... Read more

Related support groups: Warfarin, Coumadin, Atrial Fibrillation, Xarelto, Eliquis, Prevention of Thromboembolism in Atrial Fibrillation, Rivaroxaban, Apixaban, Arixtra, Fondaparinux, Jantoven, Edoxaban, Savaysa, Anisindione, Arixtra 10 mg/dose, Arixtra 7.5 mg/dose, Dicumarol, Arixtra 5 mg/dose, Miradon

Blood Thinners Overprescribed for Low-Risk Irregular Heartbeat: Study

Posted 14 Apr 2015 by Drugs.com

TUESDAY, April 14, 2015 – As many as one-quarter of people with atrial fibrillation who have a low risk of stroke are given blood-thinning drugs they likely don't need, a new study contends . Atrial fibrillation – a common form of irregular heartbeat – can cause blood clots. Those blood clots can then travel to the brain and cause a stroke. To prevent this from happening, many people with atrial fibrillation are prescribed blood thinners. However, because the drugs also have a risk of causing excessive bleeding, they generally aren't recommended for people with atrial fibrillation who have the lowest risk for stroke, the study authors explained. The study included information from nearly 11,000 atrial fibrillation patients across the United States. They were all younger than 60. They were also all considered to have a low risk of stroke, according to the researchers. Still, the study ... Read more

Related support groups: Warfarin, Coumadin, Atrial Fibrillation, Xarelto, Eliquis, Rivaroxaban, Apixaban, Arixtra, Fondaparinux, Jantoven, Savaysa, Edoxaban, Anisindione, Arixtra 10 mg/dose, Arixtra 7.5 mg/dose, Dicumarol, Arixtra 5 mg/dose, Miradon

Newer Blood Thinner Beats Heparin for Certain Heart Attacks

Posted 17 Feb 2015 by Drugs.com

TUESDAY, Feb. 17, 2015 – A blood thinner already used to treat dangerous blood clots in the limbs and lungs appears to be safer in treating certain heart attacks than the more powerful blood thinner that's traditionally used, a new Swedish study has found. Patients who received fondaparinux to treat a specific type of heart attack called non-ST-segment elevation myocardial infarction (NSTEMI) had a lower risk of major bleeding and death compared to patients who received heparin. Heparin is the blood thinner commonly used by doctors in heart attack cases, according to the study published in the Feb. 17 issue of the Journal of the American Medical Association. These findings, drawn from a large Swedish health records database, confirm the results of a 2006 clinical trial that showed that fondaparinux could be used to safely and effectively treat these types of heart attacks, said lead ... Read more

Related support groups: Heart Attack, Myocardial Infarction, Arixtra, Fondaparinux, Arixtra 10 mg/dose, Arixtra 7.5 mg/dose, Arixtra 5 mg/dose

Most Treatments for Blood Clots Appear Safe, Effective

Posted 16 Sep 2014 by Drugs.com

TUESDAY, Sept. 16, 2014 – Almost all the various treatment options for blood clots that form in veins are equally safe and effective, new research shows. In exploring the safety and effectiveness of treatments for such blood clots as deep vein thrombosis or pulmonary embolism (blood clot in a lung), Canadian researchers analyzed outcomes associated with eight blood-thinning options, including unfractionated heparin, low-molecular-weight heparin (LMWH) and fondaparinux in combination with vitamin K antagonists. The investigators also examined LMWH with dabigatran (Pradaxa), edoxaban, rivaroxaban (Xarelto), apixaban (Eliquis), as well as LMWH alone. After examining nearly 50 randomized studies, the researchers found that unfractionated heparin combined with vitamin K antagonist was associated with a higher percentage of recurrent blood clots over the course of three months than the ... Read more

Related support groups: Xarelto, Deep Vein Thrombosis (DVT), Pradaxa, Pulmonary Embolism, Eliquis, Deep Vein Thrombosis, Heparin, Rivaroxaban, Apixaban, Thrombotic/Thromboembolic Disorder, Arixtra, Hep-Pak, Fondaparinux, Dabigatran, Venous Thromboembolism, Pulmonary Thromboembolism, Heparin Sodium, Arixtra 10 mg/dose, Arixtra 7.5 mg/dose, Hep-Pak CVC

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