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Posted 10 May 2017 by Drugs.com
WEDNESDAY, May 10, 2017 – Safety problems emerge with nearly one in three prescription drugs after they've been approved by the U.S. Food and Drug Administration, a new study reveals. Researchers examined data on drugs approved by the FDA between 2001 and 2010, with follow-up through 2017. The investigators found that 32 percent of the drugs had safety issues after approval. "That is very rarely a drug withdrawal, but more commonly a black-box warning or drug safety communication issued by the FDA to let physicians and patients know that new safety information has been determined," said study leader Dr. Joseph Ross. He is an associate professor of medicine and public health at Yale University. Of 222 drugs approved by the agency during the study period, three were withdrawn, 61 received boxed warnings and 59 prompted safety communications, the findings showed. Drugs most likely to have ... Read more
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Posted 18 Dec 2015 by Drugs.com
FRIDAY, Dec. 18, 2015 – Exposure to toxic chemicals while in the womb or in early life may weaken a baby's immune system response to the tuberculosis (TB) vaccine, researchers say. The study focused on two common toxins: PCBs, an industrial chemical; and DDT, used in pesticides. These so-called "persistent" pollutants are not easily broken down and remain a health threat years after being banned. PCBs were banned in the United States in 1979. DDT is banned in the United States, but is still used in some countries to control malaria-carrying mosquitoes, the study authors, from the University of Rochester in New York, said in a university news release. The researchers analyzed blood samples and immune responses from 516 pairs of mothers and infants in an area of Slovakia heavily contaminated with environmental toxins. Each baby received the tuberculosis vaccine in their first four days ... Read more
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