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Antara News

Study Questions Rise in Use of Certain Cholesterol Drugs

Posted 22 Mar 2011 by Drugs.com

TUESDAY, March 22 – Use of a class of cholesterol-lowering drugs called fibrates is on the rise in the United States despite research that suggests they may not do much to improve health, researchers say. Fibrates are often prescribed to people with low levels of HDL ("good") cholesterol and high levels of triglycerides, a harmful form of fat circulating in the blood, experts explained. The new study isn't questioning the ability of fibrates to lower triglycerides, said lead study author Cynthia A. Jackevicius, an associate professor of pharmacy at Western University of Health Sciences in Pomona, Calif. Fibrates have also been shown to have a "modest" effect on raising HDL cholesterol. (Statins, another hugely popular family of cholesterol drugs that includes brands such as Lipitor and Zocor, are used to lower LDL, or "bad, cholesterol.) The real question, according to the study ... Read more

Related support groups: High Cholesterol, Fenofibrate, Tricor, Gemfibrozil, Trilipix, Lopid, Fenofibric Acid, Antara, Lofibra, Lipofen, Fenoglide, Dom-Fenofibrate, Triglide, Lipidil EZ, Atromid-S, Lipidil Micro, Fibricor, Clofibrate, Lipidil Supra

Herbicides, Fibrate Drugs May Block Taste Receptors

Posted 2 Dec 2009 by Drugs.com

TUESDAY, Oct. 27 – Some common herbicides and cholesterol drugs block a nutrient-sensing receptor known as T1R3, researchers report. "Compounds that either activate or block T1R3 receptors could have significant metabolic effects, potentially influencing diseases such as obesity, type II diabetes and metabolic syndrome," study author Dr. Bedrich Mosinger said in a news release. Mosinger is a geneticist at the Monell Chemical Senses Center in Philadelphia. The receptor helps the body detect sweetness and the savory taste known as umami. It's found on the tongue and also appears to be in the intestine and pancreas. According to scientists, the receptors notice that nutrients are in food and set off their processing. In the study, recently published online in the Journal of Medicinal Chemistry, researchers looked at two compounds – fibrates and phenoxy-herbicides – to see if they had an ... Read more

Related support groups: Fenofibrate, Tricor, Gemfibrozil, Lopid, Fenofibric Acid, Antara, Lofibra, Lipofen, Fenoglide, Dom-Fenofibrate, Triglide, Lipidil EZ, Atromid-S, Clofibrate, Lipidil Micro, Lipidil Supra

Drug May Lessen Amputation Risk for Diabetics

Posted 21 May 2009 by Drugs.com

THURSDAY, May 21 – The chances of having to have a limb amputated because of diabetes were reduced by 36 percent when people with type 2 diabetes were given the drug fenofibrate to lower their blood fat levels, new research has found. The study included 9,795 people, ages 50 to 75, who took either 200 milligrams of fenofibrate or a placebo daily for five years. The researchers reported that 115 people had lower-limb amputations attributed to diabetes. People with previous cardiovascular disease, microvascular disease, previous non-traumatic amputation or skin ulcer, smoking and a longer duration of diabetes were more likely to have amputations than those who had other cardiovascular problems or those who had neither cardiovascular issues or amputations. The risk of a first amputation was 36 percent lower among people taking fenofibrate than those taking the placebo. The study also ... Read more

Related support groups: Diabetes, Type 2, Antara

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Further Information

Related Condition Support Groups

Hypertriglyceridemia, Hyperlipoproteinemia, Hyperlipoproteinemia Type IIa (Elevated LDL), Hyperlipoproteinemia Type IV (Elevated VLDL), Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL), Hyperlipoproteinemia Type V (Elevated Chylomicrons + VLDL)

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