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Recurring Intestinal Infections on the Rise in U.S.: Study

Posted 7 Jul 2017 by Drugs.com

FRIDAY, July 7, 2017 – Recurring Clostridium difficile intestinal infections are rising sharply in the United States, researchers warn. These infections sicken about 500,000 people a year, cause tens of thousands of deaths, and cost the U.S. health care system about $5 billion, according to investigators at the University of Pennsylvania. C. difficile causes diarrhea, severe gut inflammation and can lead to deadly blood infections, especially in the elderly. A review of nationwide health insurance data found a nearly 200 percent increase in the annual incidence of multiple recurring C. difficile infections between 2001 and 2012. For ordinary C. difficile, incidence rose by about 40 percent. Patients with multiple recurring C. difficile infections tended to be older (average age 56 versus 49), female, and were more likely to have used antibiotics, corticosteroids or acid-reducing drugs, ... Read more

Related support groups: Infections, Bacterial Infection, Doxycycline, Bactrim, Cipro, Ciprofloxacin, Augmentin, Levaquin, Sulfamethoxazole, Levofloxacin, Minocycline, Bactrim DS, Clavulanate, Amoxicillin/Clavulanate, Tetracycline, Sulfamethoxazole/Trimethoprim, Avelox, Neomycin, Solodyn, Doryx

U.S. Hospitals Still Prescribe Too Many Antibiotics: Study

Posted 15 Jun 2017 by Drugs.com

THURSDAY, June 15, 2017 – About 20 percent of U.S. hospital patients who receive antibiotics experience side effects from the drugs, researchers report. The new study included nearly 1,500 hospitalized adults who were prescribed antibiotics. The findings revealed that one-fifth of those who experienced antibiotic-related side effects didn't require the drugs in the first place. The results add to growing evidence that antibiotics are overused, according to the Johns Hopkins Hospital researchers. "Too often, clinicians prescribe antibiotics even if they have a low suspicion for a bacterial infection, thinking that even if antibiotics may not be necessary, they are probably not harmful. But that is not always the case," said Dr. Pranita Tamma. She is director of the hospital's Pediatric Antimicrobial Stewardship Program. Antibiotics can cause real harm and doctors should always consider ... Read more

Related support groups: Infections, Bacterial Infection, Doxycycline, Bactrim, Cipro, Ciprofloxacin, Augmentin, Levaquin, Trimethoprim, Sulfamethoxazole, Nitrofurantoin, Macrobid, Bacterial Skin Infection, Levofloxacin, Minocycline, Bactrim DS, Clavulanate, Amoxicillin/Clavulanate, Tetracycline, Sulfamethoxazole/Trimethoprim

Many Americans Unaware of 'Superbug' Threat: Poll

Posted 27 Feb 2017 by Drugs.com

MONDAY, Feb. 27, 2017 – Antibiotic-resistant "superbugs" are a major public health threat, but most Americans are clueless about the dangers, a new HealthDay/Harris Poll shows. More than two-thirds of U.S. adults know "little" or "nothing" about so-called superbugs – bacterial infections that are resistant to many or all antibiotics. And around half believe, incorrectly, that antibiotics work against viruses. That's a concern because improper antibiotic use is considered the major driver of the superbug problem – a problem with deadly consequences. "This poll shows that public ignorance is a huge part of the problem," said Humphrey Taylor, chairman emeritus of The Harris Poll. "Millions of patients continue to believe that antibiotics will help them recover from colds, flu and other viral infections," Taylor said, "and they can be upset with their doctors if they will not prescribe ... Read more

Related support groups: Infections, Bacterial Infection, Doxycycline, Azithromycin, Bactrim, Cipro, Ciprofloxacin, Augmentin, Levaquin, Zithromax, Sulfamethoxazole, Erythromycin, Clarithromycin, Bacterial Skin Infection, Levofloxacin, Minocycline, Methicillin-Resistant Staphylococcus Aureus Infection, Bactrim DS, Clavulanate, Amoxicillin/Clavulanate

'Superbug' Infections Striking More U.S. Kids

Posted 24 Feb 2017 by Drugs.com

FRIDAY, Feb. 24, 2017 – A type of antibiotic-resistant bacterial infection has increased 700 percent in American children since 2007, a new investigation reveals. These infections are caused by Enterobacteriaceae bacteria – normal bacteria that can become resistant to multiple drugs. Once confined to hospitals, the tough-to-treat infections are spreading into the community at large, say researchers who evaluated eight years of data. These infections are associated with longer hospital stays and probably greater risk of death, the researchers said. "Antibiotic resistance increasingly threatens our ability to treat our children's infections," said study author Dr. Sharon Meropol. "Efforts to control this trend are urgently needed from all of us, such as using antibiotics only when necessary, and eliminating agricultural use of antibiotics in healthy animals," added Meropol. She's a ... Read more

Related support groups: Infections, Bacterial Infection, Cipro, Ciprofloxacin, Augmentin, Levaquin, Bacterial Skin Infection, Levofloxacin, Clavulanate, Amoxicillin/Clavulanate, Avelox, Neomycin, Tobramycin, Gentamicin, Ofloxacin, Moxifloxacin, Bacteremia, Amikacin, Ertapenem, Amoclan

CDC: Too Many Antibiotics Still Being Prescribed in U.S.

Posted 19 Sep 2016 by Drugs.com

MONDAY, Sept. 19, 2016 – Despite growing concerns about creating drug-resistant bacteria, overprescribing of antibiotics in U.S. hospitals didn't drop between 2006 and 2012, according to a new federal report. Over that time period, 55 percent of patients received at least one dose of antibiotics during their hospital stay, whether it was needed or not, researchers from the U.S. Centers for Disease Control and Prevention said. "Antibiotic use remains common, and use of the most powerful antibiotics is rising," said lead researcher James Baggs, a CDC epidemiologist. Although the use of antibiotics remained about the same during the study period, a significant increase was seen in the use of newer antibiotics, Baggs said. "Because inappropriate antibiotic use increases the risk of antibiotic resistance and other side effects, continued monitoring of antibiotic use is critical to future ... Read more

Related support groups: Infections, Amoxicillin, Bacterial Infection, Doxycycline, Bactrim, Cipro, Ciprofloxacin, Augmentin, Levaquin, Trimethoprim, Sulfamethoxazole, Nitrofurantoin, Macrobid, Bacterial Skin Infection, Levofloxacin, Methicillin-Resistant Staphylococcus Aureus Infection, Minocycline, Bactrim DS, Clavulanate, Amoxicillin/Clavulanate

FDA Medwatch Alert: Amikacin Sulfate Injection USP 500 mg/2 mL (250 mg/mL) and 1 Gram/4 mL (250 mg/mL) Vials by Teva: Recall - Glass Particulate Matter

Posted 3 Aug 2016 by Drugs.com

ISSUE: Teva Pharmaceuticals announced a voluntary recall of seven lots of Amikacin Sulfate Injection USP, 500 mg/2mL (250 mg/mL) and 1 gram/4mL (250 mg/mL) vials due to the potential for the presence of glass particulate matter. The administration of a glass particulate, if present in an intravenous drug, may result in local irritation or swelling in response to the foreign material. More serious potential outcomes would include blockage and clotting in blood vessels, which may be life-threatening if a critical organ is affected. See the press release for a listing of affected lot numbers. BACKGROUND: Amikacin Sulfate Injection USP is used in the short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria, and has also been shown to be effective in staphylococcal infections and may be considered as initial therapy under certain conditions in the ... Read more

Related support groups: Bacterial Infection, Amikacin, Amikin, Amikin Pediatric

FDA Medwatch Alert: Amikacin Sulfate Injection USP, 1 gram/4mL (250 mg/mL) Vials by Teva: Recall - Glass Particulate Matter

Posted 15 Mar 2016 by Drugs.com

ISSUE: Teva Pharmaceuticals announced a voluntary recall of one lot of amikacin sulfate injection USP, 1 gram/4mL (250 mg/mL) vials due to the potential presence of particulate matter identified as glass in one vial. The recalled lot # is 4750915, Expiration Date 9/2017. The administration of a glass particulate, if present in an intravenous drug, may result in local irritation or swelling in response to the foreign material. More serious potential outcomes would include blockage and clotting in blood vessels, which may be life-threatening if a critical organ is affected. BACKGROUND: Amikacin sulfate injection USP is used in the short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria, and has also been shown to be effective in staphylococcal infections and may be considered as initial therapy under certain conditions in the treatment of known or ... Read more

Related support groups: Amikacin, Amikin, Amikin Pediatric

Drug Makers, Governments Sign Deal to Fight Drug-Resistant Infections

Posted 21 Jan 2016 by Drugs.com

A groundbreaking agreement between the drug industry and governments to work together to fight drug-resistant "superbugs" is expected to be announced Thursday. Under the deal, 74 drug makers, 11 diagnostic test makers, and nine industry groups pledge to work with each other and 16 countries to prevent and improve treatment of drug-resistant infections, the Associated Press reported. These infections are a serious threat to millions of people worldwide and a number of factors contribute to the problem, including overuse of antibiotics, declining drug industry research, and few new medicines to combat bacteria, viruses, parasites and fungi. The new deal – scheduled to be announced at the World Economic Forum in Davos, Switzerland – is the first to outline how the drug industry and governments should team up to prevent more drugs from becoming ineffective, to spur development of new ... Read more

Related support groups: Doxycycline, Cephalexin, Bactrim, Cipro, Ciprofloxacin, Levaquin, Keflex, Sulfamethoxazole, Nystatin, Levofloxacin, Minocycline, Bactrim DS, Lamisil, Cefdinir, Terbinafine, Tetracycline, Sulfamethoxazole/Trimethoprim, Avelox, Sulfasalazine, Cefuroxime

Patients Can Self-Administer IV Antibiotics at Home: Study

Posted 25 Dec 2015 by Drugs.com

THURSDAY, Dec. 24, 2015 – Patients can be taught to safely self-administer long-term intravenous antibiotics at home, without the help of a health care worker, a new study suggests. The finding could have a significant impact on uninsured patients who might otherwise spend weeks in a hospital receiving IV care, according to researchers at the University of Texas Southwestern Medical Center at Dallas. "This really taps into human potential, giving a voice to the uninsured at the same time that it offers an opportunity for enormous cost savings to hospitals," study first author Dr. Kavita Bhavan, assistant professor of internal medicine, said in a medical center news release. Some infections require treatment with IV antibiotics for six weeks or more. Patients with insurance typically go home or to a nursing home and have their antibiotics administered by a home health care worker or ... Read more

Related support groups: Infections, Amoxicillin, Bacterial Infection, Doxycycline, Cephalexin, Azithromycin, Bactrim, Cipro, Ciprofloxacin, Augmentin, Levaquin, Keflex, Zithromax, Trimethoprim, Sulfamethoxazole, Nitrofurantoin, Erythromycin, Clarithromycin, Macrobid, Levofloxacin

Antibiotics May Not Help After 'Complicated' Appendectomy

Posted 2 Nov 2015 by Drugs.com

MONDAY, Nov. 2, 2015 – Antibiotics may not reduce the risk of infections in patients who undergo what's known as a "complicated" appendix removal, a new study finds. "The traditional teaching is that all patients with complicated appendicitis receive post-operative antibiotics to reduce the risk of wound infection or deep organ space infection," study lead author Dennis Kim, of the Los Angeles Biomedical Research Institute, explained in an institute news release. But is that advisory warranted? To find out, Kim's team tracked five-year outcomes for 410 patients. All of the patients had complicated appendectomies, meaning that their appendix was found to be perforated or gangrenous. About two-thirds of the patients received antibiotics after surgery. Those who received antibiotics had no fewer infections, Kim's team said, and they stayed in hospital an average of one day longer than ... Read more

Related support groups: Amoxicillin, Doxycycline, Cephalexin, Azithromycin, Bactrim, Cipro, Ciprofloxacin, Levaquin, Keflex, Zithromax, Sulfamethoxazole, Erythromycin, Clarithromycin, Levofloxacin, Minocycline, Cefdinir, Bactrim DS, Vancomycin, Tetracycline, Sulfamethoxazole/Trimethoprim

Better Control of Drug-Resistant Germs Could Save Thousands of Lives: CDC

Posted 4 Aug 2015 by Drugs.com

TUESDAY, Aug. 4, 2015 – An immediate, focused effort to halt the spread of antibiotic-resistant germs could save tens of thousands of lives and prevent hundreds of thousands of new infections over the next five years, a new government report suggests. As many as 37,000 lives could be saved, and 619,000 new infections prevented, if community health departments and health care facilities form tight support networks to quickly identify and address emerging outbreaks of antibiotic-resistant bacteria, said report author Dr. John Jernigan. He directs the Office of HAI (Health care-Associated Infections) Prevention Research and Evaluation at the U.S. Centers for Disease Control and Prevention. "When health care facilities and health departments in a community work together to share information about resistance, and then use that information to guide and target prevention efforts, then we ... Read more

Related support groups: Infections, Amoxicillin, Metronidazole, Bacterial Infection, Doxycycline, Clindamycin, Azithromycin, Bactrim, Cipro, Ciprofloxacin, Flagyl, Augmentin, Levaquin, Zithromax, Trimethoprim, Sulfamethoxazole, Nitrofurantoin, Erythromycin, Nystatin, Clarithromycin

Certain Antibiotics Linked to Hearing Loss, Mouse Study Finds

Posted 29 Jul 2015 by Drugs.com

WEDNESDAY, July 29, 2015 – A certain class of antibiotics used to treat deadly bacterial infections puts patients at high risk for hearing loss, research in mice suggests. Newborns with life-threatening infections are often given these antibiotics, the researchers said. Investigators focused on aminoglycoside antibiotics, which doctors rely on to treat meningitis, bacteremia, and respiratory infections in cystic fibrosis patients. These drugs are known to damage the sensory cells in the inner ear that detect sound and motion. Healthy mice given a low amount of an aminoglycoside developed a small degree of hearing loss. However, mice with an inflammation typical of the infections treated with aminoglycosides in humans had a much greater degree of hearing loss when they were given the antibiotics, the investigators found. Inflammation from bacterial infections boosts the uptake of ... Read more

Related support groups: Neomycin, Tobramycin, Gentamicin, Hearing Loss, Amikacin, Garamycin, Streptomycin, Tobi, Kanamycin, Paromomycin, Amikin, Humatin, Amikin Pediatric, Paromycin, Kantrex, Nebcin, Neo-Fradin, TOBI Podhaler, Cidomycin, Netromycin

Medicines Are Biggest Culprit in Fatal Allergic Reactions: Study

Posted 10 Oct 2014 by Drugs.com

THURSDAY, Oct. 9, 2014 – Although food allergies have garnered a lot of attention lately, a new study reports that medications are actually the biggest cause of sudden deaths related to allergy. Over a little more than a decade, nearly 60 percent of the allergy-related deaths were caused by medications, while less than 7 percent were caused by food allergies, the study found. "Medications can be dangerous," said study researcher Dr. Elina Jerschow, director of the Drug Allergy Center at Montefiore Medical Center and assistant professor of medicine at Albert Einstein College of Medicine, in New York City. While research from other countries has reported medications as a major culprit in anaphylaxis-related deaths, Jerschow said, the problem has been less defined in the United States. One reason is that there is no national registry for anaphylaxis deaths, she said. The study was ... Read more

Related support groups: Depo-Provera, Provera, Amoxicillin, Metronidazole, Doxycycline, Clindamycin, Cephalexin, Azithromycin, Methotrexate, Penicillin, Bactrim, Cipro, Accutane, Ciprofloxacin, Flagyl, Augmentin, Lupron, Levaquin, Keflex, Medroxyprogesterone

Hospitals' High Antibiotic Use May Boost Germs' Resistance: Study

Posted 7 Oct 2014 by Drugs.com

TUESDAY, Oct. 7, 2014 – About half of all U.S. hospital patients receive antibiotics, and these drugs are commonly the ones more likely to promote the growth of antibiotic-resistant bacteria, a new study found. "This is where the bad bugs spread, in the hospitals, because so many people are receiving antibiotics, and one of the only things that can spread are the antibiotic-resistant bugs," said Dr. Eli Perencevich, an infectious disease epidemiologist at the University of Iowa Carver College of Medicine. "We have to figure out better ways to reduce excess antibiotic use, and one way to do that is to get better at making diagnoses," he added. The study identified how many of more than 11,000 patients received antibiotics on a given day at one of 183 hospitals throughout the United States in 2011. The researchers found that 50 percent of these patients got at least one antibiotic, and ... Read more

Related support groups: Bacterial Infection, Cephalexin, Azithromycin, Bactrim, Cipro, Ciprofloxacin, Levaquin, Keflex, Zithromax, Sulfamethoxazole, Erythromycin, Clarithromycin, Levofloxacin, Methicillin-Resistant Staphylococcus Aureus Infection, Bactrim DS, Cefdinir, Vancomycin, Sulfamethoxazole/Trimethoprim, Biaxin, Avelox

U.S. Hospitals Overuse, Misuse Antibiotics, CDC Says

Posted 4 Mar 2014 by Drugs.com

TUESDAY, March 4, 2014 – Many hospitals across the United States overuse or misuse antibiotics, which fuels the growth of drug-resistant bacteria, federal health officials warned Tuesday. Doctors in some hospitals prescribe three times more antibiotics than doctors in the same departments at other medical centers, according to a new report from the U.S. Centers for Disease Control and Prevention. "We have to protect patients by protecting antibiotics," CDC Director Dr. Tom Frieden said during a noon press briefing Tuesday. "The drugs we have today are in danger, and any new drugs we get could be lost just as quickly if we don't improve the way we prescribe and use them." The agency outlined ways hospitals can improve their prescribing practices through recommended "antibiotic stewardship" programs. The CDC also is seeking a $30 million increase in the fiscal 2015 budget to help ... Read more

Related support groups: Amoxicillin, Doxycycline, Clindamycin, Cephalexin, Azithromycin, Bactrim, Cipro, Ciprofloxacin, Levaquin, Keflex, Zithromax, Sulfamethoxazole, Erythromycin, Clarithromycin, Levofloxacin, Minocycline, Bactrim DS, Tetracycline, Sulfamethoxazole/Trimethoprim, Biaxin

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