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Amevive News

Kidney Woes Tied to Raised Cancer Risk, Study Finds

Posted 12 Nov 2015 by Drugs.com

THURSDAY, Nov. 12, 2015 – Kidney failure and having a kidney transplant may increase the risk for certain types of cancer, a new study suggests. Poor kidney function and immune system-suppressing drugs may be behind this increased risk, according to Elizabeth Yanik, of the U.S. National Cancer Institute, and colleagues. For the study, published in the Nov. 12 online edition of the Journal of the American Society of Nephrology, the researchers looked at data from more than 200,000 U.S. kidney transplant candidates and recipients. Along with finding that these patients are at increased risk for certain types of cancer, the investigators also identified clear patterns of risk associated with different types of treatment. However, the associations seen in the study do not prove cause-and-effect. The risk of kidney and thyroid cancers was especially high when kidney failure patients were on ... Read more

Related support groups: Cancer, Methotrexate, Renal Failure, CellCept, Gilenya, Tysabri, Imuran, Xolair, Orencia, Chronic Kidney Disease, Revlimid, Arava, Leflunomide, Azathioprine, Afinitor, Tecfidera, Mycophenolate Mofetil, Peritoneal dialysis, Aubagio, Benlysta

Psoriasis Drug May Help Preserve Pancreas Cells in Type 1 Diabetes

Posted 21 Jul 2015 by Drugs.com

TUESDAY, July 21, 2015 – Taking two 12-week courses of alefacept – a drug already approved to treat the skin condition psoriasis – may help people with newly diagnosed type 1 diabetes preserve some function in the beta cells in the pancreas, a new study suggests. People taking the drug needed about 25 percent less insulin, and they had about half the rate of major low blood sugar episodes (hypoglycemia) compared to those who took a placebo, the study revealed. "This is the first time that documented rates of hypoglycemia – using standardized home glucometers in all patients – have shown a reduction in major hypoglycemia events following an immune intervention in new-onset [type 1 diabetes] patients," lead researcher Dr. Mario Ehlers, of the Immune Tolerance Network, said in a network news release. "This is important because frequent hypoglycemia is a common and serious complication ... Read more

Related support groups: Psoriasis, Diabetes, Type 1, Plaque Psoriasis, Amevive, Alefacept

FDA Medwatch Alert: Amevive (alefacept)

Posted 10 Nov 2005 by Drugs.com

[Posted 11/10/2005] Biogen Idec and FDA notified healthcare professionals of revisions to CONTRAINDICATIONS section of the prescribing information for Amevive, indicated for the treatment of adult patients with moderate to severe chronic plaque psoriasis who are candidates for systemic therapy or phototherapy. Amevive should not be administered to patients infected with HIV. Amevive reduces CD4+ T lymphocyte counts, which might accelerate disease progression or increase complications of disease in these patients. In addition, other sections of the product labeling were revised to reflect additional safety information. [October 2005 - Letter - Biogen Idec] Read more

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Psoriasis, Plaque Psoriasis

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