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Common Gout Drug Tied to Lower Risk of Early Death in Study

Posted 28 Mar 2014 by

FRIDAY, March 28, 2014 – A drug often used to treat gout may reduce the risk of premature death in patients with this common form of arthritis, according to a new study. Previous research has associated gout with an increased risk of early death. This study examined how allopurinol – the most widely used medication for gout – might affect that risk. Allopurinol causes a potentially fatal reaction in about one of 260 patients who uses the drug, which has made some doctors reluctant to prescribe it, according to background information in the study. The researchers looked at data from over 5,900 gout patients in the United Kingdom who were prescribed allopurinol and compared them to a group of gout patients who did not take the drug. Patients who took allopurinol were 11 percent less likely to die from all causes during the study period than those who did not take the medication. ... Read more

Related support groups: Gout, Allopurinol, Gouty Arthritis, Zyloprim, Aloprim, Lopurin

40-Year-Old Gout Drug Shows Promise Against Angina

Posted 8 Jun 2010 by

MONDAY, June 7 – A new British study suggests that a standard treatment for gout, already in use for four decades, could be an effective and less expensive alternative to conventional drugs targeting chronic stable angina. Following work with 65 heart disease patients between the ages of 18 and 85, the research team noted that six weeks of high doses (600 milligrams per day) of the gout drug allopurinol appeared to curtail the activity of a particular enzyme called xanthine oxidase, and in so doing cut back on the amount of energy the heart needs to exert whenever it beats. Exercise tests further revealed that allopurinol enabled the angina patients to get more oxygen to heart tissue plagued by blood and oxygen deprivation due to the arterial narrowing that characterizes coronary heart disease. Without treatment, this oxygen supply issue – called ischaemia – often leads to the onset ... Read more

Related support groups: Allopurinol, Angina, Zyloprim, Aloprim, Lopurin

Drug May Lower Blood Pressure in Adolescents With Hypertension

Posted 26 Aug 2008 by

TUESDAY, Aug. 26 – The drug allopurinol – a drug used to lower uric acid levels – may lower blood pressure in adolescents with high blood pressure, a new study shows. Because high blood pressure is commonly associated with high uric acid levels, some studies suggest that elevated uric acid may be one cause of high blood pressure. But since elevated uric acid levels in high blood pressure could be the result of several factors, high uric acid levels are not currently considered a true risk factor for hypertension. The current study, published in the Aug. 27 issue of the Journal of the American Medical Association, tested whether treatment with allopurinol would reduce blood pressure in 30 11- to 17-year-olds who had high uric acid levels and newly diagnosed high blood pressure. Daniel I. Feig, of the Baylor College of Medicine in Houston, and his colleagues randomly assigned the ... Read more

Related support groups: High Blood Pressure, Aloprim

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Gout, Calcium Oxalate Calculi with Hyperuricosuria, Hyperuricemia Secondary to Chemotherapy

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