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FDA OKs Parkinson's Add-On Drug

Posted 1 day 11 hours ago by Drugs.com

WEDNESDAY, March 22, 2017 – The U.S. Food and Drug Administration has approved a new drug for Parkinson's disease. Xadago (safinamide) pills were given the green light as an add-on treatment for people taking levodopa/carbidopa and experiencing "off" episodes. These are periods when medication effectiveness wanes, leading to a rise in symptoms such as tremor and difficulty walking. "Parkinson's is a relentless disease without a cure," Dr. Eric Bastings said in an FDA news release. "We are committed to helping make additional treatments for Parkinson's disease available to patients," added Bastings, deputy director of neurology products in the FDA's Center for Drug Evaluation and Research. The FDA's approval of the drug is based on two clinical trials. The studies included a total of nearly 1,200 patients who were taking levodopa and experiencing "off" time. Those who added Xadago to ... Read more

Related support groups: Flexeril, Cyclobenzaprine, Parkinson's Disease, Dry Cough, Dextromethorphan, Mucinex DM, Sinemet, Alka-Seltzer, DayQuil, Delsym, Levodopa, St. John's Wort, Daytime, Carbidopa, Bromfed DM, C-Phen DM, Tylenol Cold, Tussin DM, Rondec-DM, Promethazine DM

Are Blood Thinners Overused in Patients With Irregular Heartbeat?

Posted 6 days ago by Drugs.com

FRIDAY, March 17, 2017 – Many people living with the heart rhythm disorder known as atrial fibrillation may be taking unneeded blood thinners, a new study suggests. These blood thinners, which include aspirin, Plavix and warfarin, are believed to reduce the risk of stroke that can come with atrial fibrillation. But for many atrial fibrillation patients with a low stroke risk, the medications might actually increase both bleeding and stroke risk, researchers reported. The way most doctors decide whether a patient needs a blood thinner is by using a simple score called CHADS2, which assigns points to patients based on age and other medical risks. A score of 2 is usually needed to recommend a blood thinner, the researchers explained. But, "people are realizing that the CHADS2 scores are putting too many people above the threshold – it's pretty easy to get a 2," explained study author ... Read more

Related support groups: High Blood Pressure, Hypertension, Aspirin, Atrial Fibrillation, Plavix, Ischemic Stroke, Excedrin, Clopidogrel, Transient Ischemic Attack, Prevention of Thromboembolism in Atrial Fibrillation, Aggrenox, Alka-Seltzer, Fiorinal, Excedrin Migraine, Arthritis Pain, Ecotrin, Ischemic Stroke - Prophylaxis, Fiorinal with Codeine, Arthritis Pain Formula, Bayer Aspirin

Stent Patients Face Higher Risk of Death After Bleeding, Clots

Posted 8 days ago by Drugs.com

WEDNESDAY, March 15, 2017 – More than a year after getting stents to prop open their clogged arteries, some patients are still at increased risk of death if they suffer either blockages or bleeding events, researchers report. The researchers added that their findings highlight the need to identify which patients are more likely to benefit from prolonged anti-clotting treatment after stenting – and which are not. "Since our analysis found that the development of both ischemic [decreased blood flow] and bleeding events portend a particularly poor overall prognosis, we conclude that we must be thoughtful when prescribing any treatment... that may include bleeding risk," said study lead author Dr. Eric Secemsky. He is a fellow at Massachusetts General Hospital's division of cardiology. For the study, the researchers tracked long-term risks among people who had ischemia or bleeding events ... Read more

Related support groups: Aspirin, Ischemic Stroke, Excedrin, Aggrenox, Alka-Seltzer, Fiorinal, Excedrin Migraine, Coronary Artery Disease (CAD), Arthritis Pain, Ecotrin, Ischemic Stroke - Prophylaxis, Fiorinal with Codeine, Arthritis Pain Formula, Bayer Aspirin, Acute Coronary Syndrome, Norgesic, Soma Compound, Excedrin Extra Strength, Norgesic Forte, Percodan

Toothache? Neanderthals Might Have Reached for Aspirin, Too

Posted 15 days ago by Drugs.com

WEDNESDAY, March 8, 2017 – Dental care was decidedly primitive back in the time of the Neanderthals. But new research suggests these long-gone relatives of humans already had 21st century solutions to toothache pain – aspirin, and perhaps even penicillin. The study was led by Laura Weyrich, of the Australian Center for Ancient DNA (ACAD) at the University of Adelaide. Her team examined dental plaque from the remains of four Neanderthals found in caves in Belgium and Spain. This was the oldest such plaque ever to be genetically analyzed – between 42,000 to 50,000 years old. Weyrich said DNA analysis of ancient dental build-up can reveal a storehouse of knowledge. "Dental plaque traps microorganisms that lived in the mouth and pathogens found in the respiratory and gastrointestinal tract," she explained in a university news release. Plaque also harbors "bits of food stuck in the teeth ... Read more

Related support groups: Aspirin, Oral and Dental Conditions, Toothache, Excedrin, Gingivitis, Dental Abscess, Aggrenox, Alka-Seltzer, Fiorinal, Excedrin Migraine, Arthritis Pain, Ecotrin, Fiorinal with Codeine, Arthritis Pain Formula, Bayer Aspirin, Norgesic, Soma Compound, Periodontitis, Excedrin Extra Strength, Norgesic Forte

Study Tracks Bleeding Risk From Common Blood Thinners

Posted 28 Feb 2017 by Drugs.com

TUESDAY, Feb. 28, 2017 – Blood thinners can help prevent dangerous clots, but they also come with risks for excess bleeding. Now, new research shows that use of the medications does boost the odds of "subdural hematomas" – bleeds occurring within the skull and near the brain. And some blood thinners carry higher risk than others. The Danish research team stressed that the results don't mean patients who need blood thinners should avoid them altogether – just that their data adds to decisions around their use. "The present data add one more piece of evidence to the complex risk-benefit equation of [blood thinner] use," wrote a team led by Dr. David Gaist, of Odense University Hospital and the University of Southern Denmark. Despite the bleeding risk, "it is known that these drugs result in net benefits overall in patients with clear therapeutic indications," the study authors added. ... Read more

Related support groups: Bleeding Disorder, Aspirin, Warfarin, Coumadin, Plavix, Xarelto, Pradaxa, Eliquis, Excedrin, Clopidogrel, Aggrenox, Alka-Seltzer, Fiorinal, Excedrin Migraine, Arthritis Pain, Ecotrin, Fiorinal with Codeine, Arthritis Pain Formula, Bayer Aspirin, Norgesic

Too Many Stroke Victims Don't Get Clot-Busting Drug: Study

Posted 23 Feb 2017 by Drugs.com

THURSDAY, Feb. 23, 2017 – Stroke victims can be saved through the timely use of a powerful clot-busting drug, but certain groups of patients still aren't getting the medication quickly enough to help, a new study reveals. Blacks, Hispanics, women, seniors on Medicare and people in rural areas are less likely to be treated with tissue plasminogen activator (tPA) after suffering a stroke, researchers found. The drug works by dissolving clots that have blocked flow of blood to the brain, causing what is called an ischemic stroke. To have any effect, tPA must be administered within 4.5 hours of the start of a stroke, and it appears many patients aren't getting to the hospital and through emergency evaluation in time to receive the drug, said lead researcher Dr. Tracy Madsen. She's an assistant professor of emergency medicine at Brown University's Warren Alpert Medical School in Providence, ... Read more

Related support groups: Aspirin, Ischemic Stroke, Excedrin, Transient Ischemic Attack, Aggrenox, Alka-Seltzer, Fiorinal, Excedrin Migraine, Arthritis Pain, Ecotrin, Ischemic Stroke - Prophylaxis, Fiorinal with Codeine, Arthritis Pain Formula, Bayer Aspirin, Norgesic, Soma Compound, Excedrin Extra Strength, Norgesic Forte, Percodan, Anacin

Race May Play Role in Recurrent Stroke

Posted 23 Feb 2017 by Drugs.com

WEDNESDAY, Feb. 22, 2017 – Strokes bring with them a heightened possibility of another attack, and new research suggests black patients may be at especially high risk for recurrence. The risk of recurrent stroke was up to 50 percent higher in black seniors who'd survived a stroke compared to their white peers, according to a report to be presented Wednesday at the International Stroke Conference in Houston. The finding "suggests that neurologists need to pay extra attention to older black Americans with regard to preventing future strokes," said Dr. Andrew Rogove, who reviewed the study. He directs stroke care at Southside Hospital, in Bay Shore, N.Y. In the study, researchers led by Karen Albright, of the University of Alabama in Birmingham, looked at the odds of recurrence for ischemic strokes, which result from a blocked blood vessel. According to the American Stroke Association, ... Read more

Related support groups: Aspirin, Ischemic Stroke, Excedrin, Transient Ischemic Attack, Aggrenox, Alka-Seltzer, Fiorinal, Excedrin Migraine, Arthritis Pain, Ecotrin, Ischemic Stroke - Prophylaxis, Fiorinal with Codeine, Arthritis Pain Formula, Bayer Aspirin, Norgesic, Soma Compound, Excedrin Extra Strength, Norgesic Forte, Percodan, Anacin

Kids' OD Risk Rises When Opioids Left Out at Home

Posted 20 Feb 2017 by Drugs.com

MONDAY, Feb. 20, 2017 – A child's risk of a potentially fatal drug overdose more than doubles if a parent brings home a prescription opioid painkiller like oxycodone, codeine or morphine, a new study reports. When their mother is prescribed an opioid for pain as opposed to a non-narcotic drug like aspirin, ibuprofen or acetaminophen, young children are about two-and-a-half times more likely to accidentally overdose, the researchers found. "The opioid epidemic has not skipped children," said Dr. Yaron Finkelstein, a pediatric emergency doctor with the Hospital for Sick Children in Toronto. "They are also vulnerable to it, even as a third party or innocent bystander." Finkelstein is lead researcher on the study, published online Feb. 20 in Pediatrics. Another study in the journal helps explain the source of some of this risk. Nearly 70 percent of prescription opioids in homes with ... Read more

Related support groups: Pain, Suboxone, Oxycodone, Back Pain, Hydrocodone, Methadone, Percocet, Tramadol, OxyContin, Vicodin, Norco, Fentanyl, Opiate Dependence, Morphine, Aspirin, Codeine, Lortab, Chronic Pain, Opana, Ibuprofen

Daily Aspirin May Help Prevent Some Recurrent Miscarriages

Posted 9 Feb 2017 by Drugs.com

THURSDAY, Feb. 9, 2017 – Miscarriage is an often unexpected and traumatic event for a woman and her partner. But new research suggests that something as simple as taking a daily low-dose aspirin could help prevent a recurrence. The intervention appears to help boost live births in women with high levels of inflammation who previously lost a pregnancy, according to a research team from the U.S. National Institute of Child Health and Human Development (NICHD). One obstetrician-gynecologist said the practice is already in use in cases involving women who've miscarried in the past. "Doctors have often used baby aspirin in these patients to help achieve a healthy pregnancy," said Dr. Jennifer Wu, an ob/gyn at Lenox Hill Hospital in New York City who reviewed the new findings. "This study upholds a scientific theory to this treatment." The research was led by Lindsey Sjaarda, a staff ... Read more

Related support groups: Aspirin, Excedrin, Delivery, Aggrenox, Alka-Seltzer, Fiorinal, Excedrin Migraine, Arthritis Pain, Ecotrin, Fiorinal with Codeine, Labor Induction, Arthritis Pain Formula, Bayer Aspirin, Premature Labor, Norgesic, Soma Compound, Excedrin Extra Strength, Norgesic Forte, Percodan, Anacin

Common Painkillers Don't Ease Back Pain, Study Finds

Posted 2 Feb 2017 by Drugs.com

THURSDAY, Feb. 2, 2017 – Painkillers like aspirin, Aleve and Advil don't help most people with back pain, a new review finds. The researchers estimated that only one in six people gained a benefit from taking these nonsteroidal anti-inflammatory drugs (NSAIDs). Meanwhile, previous research has suggested that another common painkiller, Tylenol (acetaminophen), isn't very useful either, the study authors added. The findings raise the prospect that no over-the-counter painkillers really ease back pain, at least in the short term, and some may raise the risk of gastrointestinal problems. "There are other effective and safer strategies to manage spinal pain," said review author Gustavo Machado. He is a research fellow with the George Institute for Global Health in Sydney, Australia. Back and neck pain are the leading cause of pain worldwide, the researchers said. For the review, the ... Read more

Related support groups: Pain, Back Pain, Percocet, Vicodin, Norco, Aspirin, Lortab, Chronic Pain, Tylenol, Ibuprofen, Acetaminophen, Celebrex, Advil, Diclofenac, Voltaren, Aleve, Voltaren Gel, Paracetamol, Motrin, Fioricet

Study Casts Doubt on Long-Used Morning Sickness Drug

Posted 6 Jan 2017 by Drugs.com

THURSDAY, Jan. 5, 2017 – A drug commonly prescribed to ease the nausea of morning sickness may not be as effective as once believed, a new analysis suggests. Diclectin (pyridoxine-doxylamine) has been prescribed for millions of pregnant women for years. But an unpublished study from the 1970s used by the U.S. Food and Drug Administration and Health Canada to approve the drug may have overstated its benefits, the Canadian researchers behind the new research said. Study co-author Dr. Nav Persaud, a family physician at St. Michael's Hospital in Toronto, said the earlier study's data about the effectiveness of Diclectin is shaky at best. "We found two main problems with the [unpublished] study. Data was missing for 31 percent of participants. There are questions about the integrity of the data," Persaud said. "The approval and prescribing of this medication are based on this study. The ... Read more

Related support groups: Delivery, Unisom, Alka-Seltzer, Doxylamine, Vitamin/Mineral Supplementation during Pregnancy/Lactation, Vitamin B6, Sleep Aid, All-Nite, Diclegis, Night Time, Cesarean Section, Doxylamine/pyridoxine, Dextromethorphan/Doxylamine, Prematurity/Underweight in Infancy, Nyquil Cold & Flu, Nytol Maximum Strength, Nighttime Sleepaid, Lortuss DM, Doxylamine/phenylephrine, Tylenol Sinus NightTime

Daily Low-Dose Aspirin May Cut Pancreatic Cancer Risk

Posted 20 Dec 2016 by Drugs.com

TUESDAY, Dec. 20, 2016 – There's evidence that daily low-dose aspirin may decrease the risk of pancreatic cancer, according to a new study. The Chinese-based study couldn't prove cause-and-effect. However, "the balance of evidence shows that people who use aspirin to reduce risk for cardiovascular disease or colorectal cancer can feel positive that their use likely also lowers their risk for pancreatic cancer," said study lead author Dr. Harvey Risch. He's professor of epidemiology at the Yale School of Public Health and Yale Cancer Center in New Haven, Conn. According to the American Cancer Society, about 53,000 Americans will be diagnosed with pancreatic cancer this year, and almost 42,000 will die from the disease. Pancreatic cancer is often a "silent killer" because symptoms do not emerge until the tumor is advanced. The new study tracked 761 people diagnosed with pancreatic cancer ... Read more

Related support groups: Aspirin, Excedrin, Colorectal Cancer, Aggrenox, Alka-Seltzer, Pancreatic Cancer, Fiorinal, Excedrin Migraine, Prevention of Cardiovascular Disease, Arthritis Pain, Ecotrin, Fiorinal with Codeine, Arthritis Pain Formula, Bayer Aspirin, Cardiovascular Risk Reduction, Norgesic, Soma Compound, Excedrin Extra Strength, Norgesic Forte, Percodan

Everyday Pain Relievers May Be Linked to Hearing Loss in Some Women

Posted 19 Dec 2016 by Drugs.com

MONDAY, Dec. 19, 2016 – Long-term use of over-the-counter pain relievers may be associated with increased risk of hearing loss in some women, a new study says. Women who used ibuprofen (Advil, Motrin) or acetaminophen (Tylenol) for six years or more were more likely to suffer hearing loss than those who used the pain relievers for a year or less, said researchers from Brigham and Women's Hospital in Boston. They found no significant association between long-term aspirin use and hearing loss. "Although the magnitude of higher risk of hearing loss with analgesic use was modest, given how commonly these medications are used, even a small increase in risk could have important health implications," study senior author Dr. Gary Curhan said in a hospital news release. "Assuming causality, this would mean that approximately 16.2 percent of hearing loss occurring in these women could be due to ... Read more

Related support groups: Pain, Percocet, Vicodin, Norco, Aspirin, Lortab, Tylenol, Ibuprofen, Acetaminophen, Advil, Paracetamol, Motrin, Fioricet, Excedrin, Endocet, Darvocet-N 100, Acetaminophen/Hydrocodone, Tylenol PM, Tylenol with Codeine, Percocet 10/325

Wider Low-Dose Aspirin Use Would Save U.S. $692 Billion: Study

Posted 30 Nov 2016 by Drugs.com

WEDNESDAY, Nov. 30, 2016 – Taking low-dose aspirin daily can reduce older Americans' risk of heart disease and cancer, and lead to significant savings in health care spending, a new study contends. University of Southern California researchers used national data to assess the long-term benefits of daily aspirin usage. They calculated that taking low-dose aspirin every day would prevent 11 cases of heart disease and four cases of cancer for every 1,000 Americans ages 51 to 79. "Although the health benefits of aspirin are well-established, few people take it," said study lead author Dr. David Agus. He's the founding director and CEO of the university's Lawrence J. Ellison Institute for Transformative Medicine. "Our study shows multiple health benefits and a reduction in health care spending from this simple, low-cost measure that should be considered a standard part of care for the ... Read more

Related support groups: Aspirin, Ischemic Stroke, Excedrin, Transient Ischemic Attack, Aggrenox, Alka-Seltzer, Fiorinal, Excedrin Migraine, Prevention of Cardiovascular Disease, Arthritis Pain, Ecotrin, Ischemic Stroke - Prophylaxis, Fiorinal with Codeine, Arthritis Pain Formula, Bayer Aspirin, Cardiovascular Risk Reduction, Norgesic, Soma Compound, Excedrin Extra Strength, Norgesic Forte

Take Meds as Directed to Boost Survival After Heart Procedures

Posted 24 Oct 2016 by Drugs.com

THURSDAY, Oct. 20, 2016 – Taking medications as prescribed improves outcomes for heart procedure patients, a new study finds. Researchers looked at 973 heart bypass patients and 2,255 patients who underwent angioplasty and stenting to reopen clogged heart arteries. Heart bypass surgery is when surgeons take a piece of blood vessel from somewhere else in the body to bypass a blocked portion of the heart's artery. Angioplasty is performed using a thin catheter that's threaded through the blood vessels to the heart. A balloon on the end of the catheter is inflated to open the narrowed blood vessel. Sometimes a stent (a mesh or wire tube) will be left in the blood vessel to keep it open. Prescribed medications in the study included cholesterol-lowering statins, blood thinners and beta blockers. Follow-up information was collected 12 to 18 months after the heart procedures. Overall, ... Read more

Related support groups: Surgery, Aspirin, Metoprolol, Atenolol, Lipitor, Propranolol, Simvastatin, Crestor, Atorvastatin, Bystolic, Carvedilol, Pravastatin, Bisoprolol, Excedrin, Coreg, Inderal, Sotalol, Zocor, Lovastatin, Toprol-XL

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