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Celebrex May Not Pose Bigger Heart Risk Than Similar Drugs: Study

Posted 18 days ago by Drugs.com

MONDAY, Nov. 14, 2016 – Some people taking the pain reliever Celebrex may not have a greater risk for heart problems than those taking other nonsteroidal anti-inflammatory drugs (NSAIDs), a new study says. Celebrex (celecoxib) is a COX-2 inhibitor. That's the same class of drugs as Vioxx and Bextra, which were pulled from the market in 2004 and 2005, respectively, because they were linked to heart problems. Celebrex didn't seem to share the same issues, so has remained available. And the new trial's "primary message is that celecoxib is not riskier for the heart than other NSAIDs," said study director Dr. Steven Nissen in a Cleveland Clinic news release. Nissen is chair of the Department of Cardiovascular Medicine. Nissen's prior research was instrumental in uncovering the cardiovascular risks associated with COX-2 inhibitors. The new study seems to reaffirm Celebrex's safety profile. ... Read more

Related support groups: Ibuprofen, Naproxen, Heart Disease, Celebrex, Advil, Aleve, Motrin, Vicoprofen, Naprosyn, Prevention of Cardiovascular Disease, Advil PM, Vimovo, Treximet, Advil Cold and Sinus, Vioxx, Celecoxib, Naprelan '375', Cardiovascular Risk Reduction, Naprelan, Hydrocodone/Ibuprofen

Health Tip: Avoid These 5 Pre-Bedtime Don'ts

Posted 2 Oct 2016 by Drugs.com

-- Your habits just before you slip into bed could be sabotaging your night of sleep. The National Sleep Foundation says do NOT: Take any over-the-counter medications that contain pseudoephedrine, found in common cold medicines, which can keep you awake. Opt for a nighttime formula that may help you feel drowsy. Text, watch TV or spend time on the computer shortly before bed. Take a hot shower or bath just before bed. It's best to do so about an hour before you plan to sleep, as that gives your body temperature time to drop again. Indulge in a greasy, fattening, salty bedtime snack, which can be stimulating and trigger nightmares. Drink caffeine beyond the morning, as it can stay in your system for as long as 12 hours. Read more

Related support groups: Sleep Disorders, Insomnia, Fatigue, Sta-D, Caffeine, Pseudoephedrine, Fioricet, Excedrin, Claritin-D, Alert, Mucinex D, DayQuil, Fiorinal, Allegra-D, Excedrin Migraine, Bromfed DM, Cafergot, Tylenol Cold, Advil Cold and Sinus, Lodrane

Could Prescribed NSAID Painkillers Raise Heart Failure Risk?

Posted 29 Sep 2016 by Drugs.com

WEDNESDAY, Sept. 28, 2016 – Use of prescription-strength ibuprofen, naproxen and other commonly used pain relievers may be tied to a higher risk of heart failure, researchers report. Medicines like these fall into a category of painkillers known as non-steroidal anti-inflammatory drugs (NSAIDs). These medications may raise a person's relative risk of heart failure by nearly 20 percent, according to the analysis of medical records for nearly 10 million patients. That risk increases with the amount of NSAIDs a person is taking, said study author Andrea Arfe, a Ph.D. student at University of Milano-Bicocca, in Italy. A person's risk of hospitalization for heart failure doubles for some NSAIDs used at very high doses, including diclofenac (Cataflam or Voltaren), etoricoxib (Arcoxia), indomethacin (Indocin), and piroxicam (Feldene), Arfe said. Also, "our findings – which focused only on ... Read more

Related support groups: Ibuprofen, Naproxen, Meloxicam, Diclofenac, Advil, Heart Failure, Voltaren, Congestive Heart Failure, Aleve, Mobic, Motrin, Indomethacin, Toradol, Etodolac, Vicoprofen, Nabumetone, Flector, Ketorolac, Arthrotec, Naprosyn

Beware of Bleeding Risks With Antacids Containing Aspirin

Posted 6 Jun 2016 by Drugs.com

MONDAY, June 6, 2016 – Antacids that contain aspirin may cause stomach or intestinal bleeding in rare cases, U.S. Food and Drug Administration officials said Monday. Since it issued a warning about serious bleeding risk with aspirin in 2009, the FDA has recorded eight new cases of serious bleeding caused by aspirin-containing antacid products sold over-the-counter, which include Alka Seltzer and Bromo Seltzer. In some of those cases, patients required a blood transfusion, the agency said in a news release. "Take a close look at the Drug Facts label, and if the product has aspirin, consider choosing something else for your stomach symptoms," Dr. Karen Murry Mahoney, deputy director of the division of nonprescription drug products, said in the release. "Unless people read the Drug Facts label when they're looking for stomach symptom relief, they might not even think about the possibility ... Read more

Related support groups: GERD, Aspirin, Ibuprofen, Naproxen, Advil, Aleve, Indigestion, Alcohol Dependence, Motrin, Excedrin, Tums, Milk of Magnesia, Vicoprofen, Aggrenox, Alka-Seltzer, Caltrate, Alcoholism, Fiorinal, Duodenitis/Gastritis, Excedrin Migraine

Many Chronic Pain Sufferers May Overuse Nonprescription Painkillers

Posted 26 Jan 2016 by Drugs.com

MONDAY, Jan. 25, 2016 – Many people with chronic pain ignore dosing instructions on over-the-counter pain medicines and put themselves at risk for an overdose, a new survey suggests. An overdose of these medicines can result in serious side effects, such as stomach bleeding, ulcers, liver damage and even death, according to the American Gastroenterological Association (AGA). The AGA-commissioned poll of more than 1,000 U.S. adults aged 30 and older and 251 gastroenterologists found that 43 percent of chronic pain sufferers said they knowingly have taken more than the recommended dose of an over-the-counter (OTC) pain medicine at some point. Common types of OTC pain medicines include acetaminophen (Tylenol) and nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil, Motrin), naproxen (Aleve) and aspirin. "Pain is incredibly personal, but taking more than the recommended ... Read more

Related support groups: Pain, Suboxone, Oxycodone, Back Pain, Hydrocodone, Methadone, Percocet, Tramadol, OxyContin, Vicodin, Norco, Fentanyl, Morphine, Aspirin, Codeine, Lortab, Tylenol, Chronic Pain, Muscle Pain, Opana

Prescription Naproxen as Good as Narcotic Painkillers for Low Back Pain: Study

Posted 20 Oct 2015 by Drugs.com

TUESDAY, Oct. 20, 2015 – Naproxen – a drug available over-the-counter and by prescription – appears to provide as much relief for low back pain as a narcotic painkiller or a muscle relaxant, a new study suggests. The study compared the use of prescription-strength naproxen (Naprosyn) alone to the use of naproxen with the narcotic painkiller oxycodone with acetaminophen (Percocet), or the muscle relaxant cyclobenzaprine (Amrix). Patients who took a combination of drugs fared no better than when they took naproxen alone, the researchers said. "Acute low back pain is a frustrating condition," said lead researcher Dr. Benjamin Friedman, an associate professor of emergency medicine at Montefiore Medical Center and Albert Einstein College of Medicine in New York City. Many patients have already taken over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs), such as naproxen (Aleve) ... Read more

Related support groups: Pain, Oxycodone, Back Pain, Percocet, OxyContin, Vicodin, Norco, Lortab, Tylenol, Chronic Pain, Naproxen, Flexeril, Acetaminophen, Cyclobenzaprine, Roxicodone, Aleve, Paracetamol, Fioricet, Excedrin, Endocet

Slow Progress on Curbing Wasteful, 'Low-Value' Health Care Practices: Study

Posted 12 Oct 2015 by Drugs.com

MONDAY, Oct. 12, 2015 – As health care budgets get tighter across the United States, there's been a renewed focus on ridding the system of procedures that give patients little real benefit for the time and money spent. Now, a new study suggests that the use of at least three health care services deemed to be "low value" have dropped over the past few years. However, there were only slight decreases – and even increases – in the use of many other low-value services, the report found. In 2009, the National Physicians Alliance piloted an effort called the Choosing Wisely Campaign, aimed at cutting overuse and waste out of the health care system. The campaign lists hundreds of widely used medical practices and procedures that experts say are of little clinical good to patients. In the new study, a team led by Abiy Agiro, of HealthCore in Wilmington, Del., examined seven health services ... Read more

Related support groups: High Blood Pressure, Back Pain, Hypertension, Ibuprofen, Naproxen, Advil, Sciatica, Heart Failure, Congestive Heart Failure, Aleve, Renal Failure, Motrin, Vicoprofen, Human Papilloma Virus, Chronic Kidney Disease, Naprosyn, Left Ventricular Dysfunction, Advil PM, Treximet, Vimovo

Health Tip: Avoid These Things Before Bedtime

Posted 20 Jul 2015 by Drugs.com

-- If you're not getting enough sleep, it could be due to your activities before you hit the hay. The National Sleep Foundation warns against: Taking medications that contain pseudoephedrine, a stimulant. If you need relief from cold or allergy symptoms, opt for an antihistamine designed for night-time use. Don't watch TV, work at a computer or use a tablet or smartphone. Light from these screens can over-stimulate your brain. Opt for a book or music instead. Don't take a hot bath just before bed. Bathe at least an hour before so your body has time to cool off before sleep. Don't go to sleep with a full belly, especially if it's loaded with foods high in fat and salt. Don't drink beverages that contain caffeine after the morning. Caffeine can stay in your system for up to 12 hours. Read more

Related support groups: Sleep Disorders, Insomnia, Benadryl, Hydroxyzine, Zyrtec, Sta-D, Promethazine, Claritin, Allegra, Loratadine, Diphenhydramine, Pseudoephedrine, Phenergan, Cetirizine, Vistaril, Sudafed, Cyproheptadine, Atarax, NyQuil, Claritin-D

Antidepressant, Painkiller Combo May Raise Risk of Brain Bleed

Posted 14 Jul 2015 by Drugs.com

TUESDAY, July 14, 2015 – Taking both an antidepressant and a painkiller such as ibuprofen or naproxen may increase risk of a brain hemorrhage, a new study suggests. Korean researchers found that of more than 4 million people prescribed a first-time antidepressant, those who also used nonsteroidal anti-inflammatory drugs (NSAIDs) had a higher risk of intracranial hemorrhage within the next month. Intracranial hemorrhage refers to bleeding under the skull that can lead to permanent brain damage or death. The findings, published online July 14 in BMJ, add to a week of bad news on NSAIDs, which include over-the-counter pain relievers such as aspirin, ibuprofen (Motrin, Advil) and naproxen (Aleve). Last Thursday, the U.S. Food and Drug Administration strengthened the warning labels on some NSAIDs, emphasizing that the drugs can raise the risk of heart attack and stroke. As far as the new ... Read more

Related support groups: Lexapro, Zoloft, Wellbutrin, Cymbalta, Bleeding Disorder, Effexor, Prozac, Celexa, Citalopram, Paxil, Trazodone, Sertraline, Pristiq, Ibuprofen, Bupropion, Amitriptyline, Naproxen, Fluoxetine, Viibryd, Venlafaxine

Experts Urge Caution With Popular Painkillers After FDA Warning

Posted 10 Jul 2015 by Drugs.com

FRIDAY, July 10, 2015 – People who regularly reach for widely used painkillers like ibuprofen and naproxen may need to think carefully before they pop those pills, heart experts say. Mounting evidence has shown that chronic use of non-steroidal anti-inflammatory drugs (NSAIDs) can raise a person's risk of heart attack and stroke. The evidence is strong enough that the U.S. Food and Drug Administration on Thursday ordered drug makers to toughen warning labels on both prescription and over-the-counter NSAIDs. The tougher warning does not include aspirin, an NSAID that has been shown to lower heart risks in some patients. Most people who occasionally take ibuprofen (Advil, Motrin) or naproxen (Aleve) for infrequent headaches or pain don't have to worry, as long as they follow the dosage directions on the bottle, said Dr. Richard Chazal, president-elect of the American College of ... Read more

Related support groups: Pain, Ibuprofen, Naproxen, Meloxicam, Celebrex, Diclofenac, Advil, Voltaren, Aleve, Mobic, Voltaren Gel, Motrin, Indomethacin, Toradol, Etodolac, Vicoprofen, Nabumetone, Flector, Flector Patch, Ketorolac

FDA Strengthens Heart Attack, Stroke Warning for Popular Painkillers

Posted 10 Jul 2015 by Drugs.com

THURSDAY, July 9, 2015 – The U.S Food and Drug Administration on Thursday strengthened the warning labels for widely used painkillers like ibuprofen and naproxen, saying they can increase the risk of heart attack or stroke. The FDA is asking people to think carefully about their use of nonsteroidal anti-inflammatory drugs (NSAIDs), particularly if they've already had a heart attack, according to a consumer update on the agency's website. The agency said it is taking this action based on recent data that shows the risk of heart attack or stroke can increase even after using NSAIDs for a short time. "They used to say they might cause risk of heart attack or stroke. Now we are saying they do cause increased risk of heart attack and stroke," FDA spokesman Eric Pahon told NBC News. In particular, people should avoid taking multiple products that contain NSAIDs, according to the revised FDA ... Read more

Related support groups: Ibuprofen, Naproxen, Meloxicam, Celebrex, Diclofenac, Advil, Voltaren, Aleve, Mobic, Voltaren Gel, Motrin, Indomethacin, Toradol, Etodolac, Vicoprofen, Nabumetone, Flector, Flector Patch, Ketorolac, Arthrotec

FDA Medwatch Alert: Non-aspirin Nonsteroidal Anti-inflammatory Drugs (NSAIDs): Drug Safety Communication - FDA Strengthens Warning of Increased Chance of Heart Attack or Stroke

Posted 10 Jul 2015 by Drugs.com

[Posted 07/09/2015] ISSUE:  FDA is strengthening an existing label warning that non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) increase the chance of a heart attack or stroke. Based on FDAs comprehensive review of new safety information, FDA is requiring updates to the drug labels of all prescription NSAIDs. As is the case with current prescription NSAID labels, the Drug Facts labels of over-the-counter (OTC) non-aspirin NSAIDs already contain information on heart attack and stroke risk. FDA will also request updates to the OTC non-aspirin NSAID Drug Facts labels. See the FDA Drug Safety Communication (Table 1) for a list of non-aspirin nonsteroidal anti-inflammatory drug products. Prescription NSAID labels will be revised to reflect the following information: The risk of heart attack or stroke can occur as early as the first weeks of using an NSAID. The risk may increase ... Read more

Related support groups: Ibuprofen, Naproxen, Meloxicam, Celebrex, Advil, Diclofenac, Voltaren, Aleve, Mobic, Voltaren Gel, Motrin, Indomethacin, Toradol, Etodolac, Vicoprofen, Nabumetone, Flector, Flector Patch, Ketorolac, Arthrotec

Common Painkillers May Help Prevent Certain Skin Cancers, Study Finds

Posted 18 Dec 2014 by Drugs.com

THURSDAY, Dec. 18, 2014 – Common painkillers, including ibuprofen, might slightly reduce your risk of developing a form of skin cancer, researchers say. Use of ibuprofen (Advil, Motrin) and naproxen (Aleve) appear to reduce the risk of squamous cell skin cancer by 15 percent, the researchers concluded after reviewing nine prior studies. Squamous cell skin cancer is usually caused by sun exposure. These painkillers "have potential as part of a skin cancer-prevention strategy," said review co-author Catherine Olsen, a senior research officer with QIMR Berghofer Medical Research Institute in Brisbane, Queensland, Australia. But Olsen and other experts aren't ready to recommend popping these or other nonsteroidal anti-inflammatory drugs (NSAIDs) to prevent skin cancer. For one thing, these drugs are associated with risks of their own. "Don't rely on aspirin or other nonsteroidal ... Read more

Related support groups: Ibuprofen, Naproxen, Advil, Aleve, Motrin, Vicoprofen, Skin Cancer, Naprosyn, Advil PM, Treximet, Vimovo, Advil Cold and Sinus, Naprelan '375', Squamous Cell Carcinoma, Naprelan, Hydrocodone/Ibuprofen, Anaprox, Duexis, Anaprox-DS, Ibuprofen PMR

Medication Errors Occur Every 8 Minutes in U.S. Children

Posted 20 Oct 2014 by Drugs.com

MONDAY, Oct. 20, 2014 – A child receives the wrong medication or the wrong dosage every eight minutes in the United States, according to a recent study. Nearly 700,000 children under 6 years old experienced an out-of-hospital medication error between 2002 and 2012. Out of those episodes, one out of four children was under a year old. As the age of children decreased, the likelihood of an error increased, the study found. Though 94 percent of the mistakes didn't require medical treatment, the errors led to 25 deaths and about 1,900 critical care admissions, according to the study. "Even the most conscientious parents make errors," said lead author Dr. Huiyun Xiang, director of the Center for Pediatric Trauma Research at Nationwide Children's Hospital in Columbus, Ohio. That conscientiousness may even lead to one of the most common errors: Just over a quarter of these mistakes involved a ... Read more

Related support groups: Xanax, Klonopin, Clonazepam, Seroquel, Ativan, Valium, Abilify, Lorazepam, Alprazolam, Azithromycin, Diazepam, Soma, Benadryl, Flexeril, Latuda, Cyclobenzaprine, Baclofen, Zyprexa, Hydroxyzine, Risperdal

FDA Panel Sees No Heart-Safety Advantage With Naproxen

Posted 11 Feb 2014 by Drugs.com

TUESDAY, Feb. 10, 2014 – The science isn't convincing enough to say that naproxen – the key pain reliever in Aleve – is safer for the heart than other popular anti-inflammatory drugs such as ibuprofen (Advil and Motrin), U.S. health advisers ruled Tuesday. The decision was highly anticipated, since a vote in favor of naproxen's superiority might have led to a product labeling change, experts said. However, the 16-9 vote by the advisory panel to the U.S. Food and Drug Administration did not find enough evidence to put naproxen ahead of other pain relievers in terms of heart risk. The FDA isn't required to follow the recommendations of its advisory committees but it usually does so. Naproxen, ibuprofen and aspirin fall under the umbrella term nonsteroidal anti-inflammatory drugs (NSAIDs). Millions of people take these medicines to help relieve muscle aches, headaches and pain from ... Read more

Related support groups: Naproxen, Aleve, Naprosyn, Vimovo, Treximet, Naprelan '375', Naprelan, Anaprox, Anaprox-DS, Midol Extended Relief, Esomeprazole/naproxen, Aleve Sinus & Headache, Naproxen/Sumatriptan, Prevacid NapraPAC, EC-Naprosyn, Prevacid NapraPAC 500, Aflaxen, Lansoprazole/Naproxen, Aleve Cold and Sinus, Naprelan '500'

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