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Most Adult Survivors of Childhood Cancers Enjoy Good Sexual Health

Posted 6 Feb 2017 by Drugs.com

MONDAY, Feb. 6, 2017 – Treatment received in childhood to help fight cancer can have an impact on sexual health in adulthood, a new report suggests. However, the study also found that most adult survivors of childhood cancer report having satisfying sexual and romantic lives. "As positive as it is to see this, we still should be closely monitoring sexual health in adults who did have cancer treatment as children, especially those needing high-dose neurotoxic [brain-harming] treatments," said Dr. Matthew Lorber, who reviewed the new findings. He directs child and adolescent psychiatry at Lenox Hill Hospital in New York City. The new research was published online Feb. 6 in the journal Cancer and was led by Vicky Lehmann, of Nationwide Children's Hospital and Ohio State University in Columbus. Lehmann's team noted that treatment for childhood cancer can harm the developing brain in a way ... Read more

Related support groups: Birth Control, Contraception, Cancer, Erectile Dysfunction, Methotrexate, Sexually Transmitted Diseases, Female Infertility, Leukemia, Fluorouracil, Xeloda, Hydroxyurea, Ovulation Induction, Mercaptopurine, Hydrea, Dacogen, Capecitabine, Gemcitabine, Gemzar, Sexual Deviations or Disorders, Alimta

Half Report Severe Side Effects From Breast Cancer Therapy

Posted 24 Jan 2017 by Drugs.com

TUESDAY, Jan. 24, 2017 – About half of early stage breast cancer patients experience severe side effects from their treatment, a new study finds. "It's in patients' best interest to receive their treatments on time and on schedule, whenever possible, to give them the best possible outcome," said study author Dr. Steven Katz. He's professor of health management and policy at the University of Michigan. "Unscheduled care for toxicities [side effects] – including clinic visits, emergency department visits and hospital stays – are expensive, inconvenient and disruptive to both doctors and patients. We need to avoid them whenever possible," Katz said in a university news release. For the study, researchers surveyed almost 2,000 early stage breast cancer patients an average of seven months after diagnosis. The women were asked to rate the severity of seven common treatment side effects: ... Read more

Related support groups: Surgery, Breast Cancer, Fluorouracil, Efudex, Carac, Breast Cancer, Metastatic, Herceptin, Taxol, Breast Cancer - Adjuvant, Taxotere, Carboplatin, Cytoxan, Cyclophosphamide, Paclitaxel, Breast Cancer, Prevention, Adriamycin, Breast Cancer - Palliative, Fluoroplex, Doxorubicin, Docetaxel

Skin Cancer Cream Linked to 5 Dog Deaths: FDA

Posted 20 Jan 2017 by Drugs.com

THURSDAY, Jan. 19, 2017 – Five dogs have died from exposure to a skin cancer cream prescribed for people, according to the U.S. Food and Drug Administration. Ingesting very small amounts of the drug – fluorouracil topical cream USP 5% (5-FU) – can sicken or kill family pets, said the FDA. "Although the FDA has not to date received any reports involving cats, they are also expected to be extremely sensitive to fluorouracil cream," the agency said in a news release. The drug is also marketed under the brand names Carac, Efudex and Fluoroplex, the FDA said. It's used to treat precancerous sun-damaged skin as well as some basal cell skin cancers, according to the American Cancer Society. In one case, a dog merely punctured the tube of fluorouracil in its mouth before its owner could grab it. The pooch died 12 hours later, after vomiting and suffering seizures. In another instance, a dog ... Read more

Related support groups: Fluorouracil, Efudex, Basal Cell Carcinoma, Carac, Melanoma, Skin Cancer, Melanoma - Metastatic, Fluoroplex, Tolak, Adrucil, History - Skin Cancer, Efudex Occlusion Pack, Fluorac, Diclofenac/fluorouracil

U.S. Pays Highest Prices for Cancer Meds: Study

Posted 6 Jun 2016 by Drugs.com

MONDAY, June 6, 2016 – The United States pays the highest prices in the world for generic and brand-name cancer drugs, a new study has found. However, as the world's wealthiest nation, the United States is better able to pay for those pricey drugs than poorer countries with somewhat lower medication prices, added study lead author Dr. Daniel Goldstein. People in China and India are much less able to afford cancer drugs than Americans, he said, even though U.S. monthly drug prices are about three to six times higher in the United States. That doesn't mean America came out on top in overall drug affordability, however. Developed nations such as Australia, England and Israel had the "best deal" in the world on cancer drugs, thanks to government programs that regulate drug pricing, the study found. "America is the wealthiest nation, but its drug prices are significantly higher – so much ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Breast Cancer, Accutane, Lupron, Medroxyprogesterone, Tamoxifen, Arimidex, Tretinoin, Fluorouracil, Lupron Depot, Femara, Gleevec, Rituxan, Lung Cancer, Isotretinoin, Colorectal Cancer, Claravis

'Precision' Cancer Treatment May Extend Lives

Posted 20 May 2016 by Drugs.com

THURSDAY, May 19, 2016 – "Precision" cancer treatment that's guided by genetic clues from the patient's own tumor appears to outperform traditional chemotherapy, a new research review finds. Patients given precision – or personalized – treatment experienced a tumor shrinkage rate six times that attained by regular chemotherapy. But, that only happened if doctors used genetic information to choose the appropriate targeted therapy, said lead researcher Maria Schwaederle. Those patients also experienced nearly double the length of time before their cancer resumed growing, according to the analysis of nearly 350 clinical trials. "It is not just that the therapies are better, but that targeted therapies must be given to the right patients," said Schwaederle, who's with the University of California, San Diego School of Medicine's Center for Personalized Cancer Therapy. She will present ... Read more

Related support groups: Cancer, Methotrexate, Breast Cancer, Accutane, Tretinoin, Fluorouracil, Gleevec, Lung Cancer, Colorectal Cancer, Isotretinoin, Claravis, Tarceva, Xeloda, Skin Cancer, Tasigna, BCG, Revlimid, Hydroxyurea, Sprycel, Herceptin

HIV Patients Less Likely to Get Treatment for Cancer: Study

Posted 17 May 2016 by Drugs.com

TUESDAY, May 17, 2016 – While powerful HIV medications are granting longer lives to many people infected with the virus, a new U.S. study shows these same patients are less likely to get treatment for cancer if it develops. It's not clear why the difference exists. It could reflect the decisions of physicians, patients or both. Whatever the case, the finding confirms that the gap persists even when patients have private insurance or are otherwise healthy, the study authors said. Previous research has suggested that "people with well-controlled HIV infection should be treated similarly to patients without HIV," said study author Dr. Gita Suneja. However, "even looking at cancer patients with private health insurance only, we saw that those with HIV infection were less likely to receive cancer treatment for many common cancer types," said Suneja. She is an assistant professor of ... Read more

Related support groups: Cancer, Methotrexate, HIV Infection, Fluorouracil, Lung Cancer, Xeloda, Hydroxyurea, Mercaptopurine, Hydrea, Carboplatin, Cisplatin, Cytoxan, Dacogen, Temodar, Bendamustine, Cyclophosphamide, Oxaliplatin, Capecitabine, Treanda, Gemcitabine

Could Talk Therapy Ease Chemo-Related Memory Issues?

Posted 2 May 2016 by Drugs.com

MONDAY, May 2, 2016 – A type of psychotherapy might help cancer survivors deal with the long-term thinking problems some experience after chemotherapy, researchers say. It's estimated that about half of those who undergo chemotherapy for cancer develop what's often called "chemo brain." For instance, they may have trouble following conversations or remembering the steps in a project, according to background notes with the new study. Although usually mild, these changes can affect quality of life, job performance and relationships, said the researchers from the Eastern Maine Medical Center and Lafayette Family Cancer Center in Bangor, Maine. The researchers developed a cognitive-behavioral therapy (CBT) program called Memory and Attention Adaptation Training to help cancer survivors prevent or manage these memory problems. Their study involved 47 breast cancer survivors who underwent ... Read more

Related support groups: Cancer, Methotrexate, Breast Cancer, Prostate Cancer, Fluorouracil, Gleevec, Lung Cancer, Renal Cell Carcinoma, Colorectal Cancer, Non-Small Cell Lung Cancer, Breast Cancer, Metastatic, Brain Tumor, Melanoma, Xeloda, Pancreatic Cancer, Skin Cancer, Tasigna, Ovarian Cancer, Endometrial Cancer, Hydroxyurea

Fewer Childhood Cancer Survivors Dying From 'Late' Effects

Posted 13 Jan 2016 by Drugs.com

WEDNESDAY, Jan. 13, 2016 – Fewer childhood cancer survivors are dying years later from lingering effects of the treatment that conquered their cancer, a new study finds. Experts called the report, published in the Jan. 14 issue of the New England Journal of Medicine, "very good news." "The findings substantiate what experts in the field have hoped would be true," said lead researcher Dr. Gregory Armstrong, of St. Jude Children's Research Hospital, in Memphis, Tenn. Survival rates from many childhood cancers are high, but survivors still face what doctors call "late effects" – health problems that develop months to years after the cancer treatment has ended. Among U.S. children who survived cancer back in the 1970s and '80s, 18 percent died within the next 25 years, Armstrong said. Sometimes, the initial cancer comes back. Often though, the health issues are related to the very ... Read more

Related support groups: Cancer, Methotrexate, Fluorouracil, Xeloda, Hydroxyurea, Mercaptopurine, Hydrea, Carboplatin, Cisplatin, Cytoxan, Dacogen, Cyclophosphamide, Temodar, Bendamustine, Oxaliplatin, Capecitabine, Treanda, Hodgkin's Lymphoma, Acute Lymphoblastic Leukemia, Gemzar

Childhood Cancer Treatment May Raise Adult Heart Disease Risk

Posted 5 Jan 2016 by Drugs.com

MONDAY, Jan. 4, 2016 – Children who survive cancer may face a higher risk of heart disease as adults, new research suggests. The lingering effects of the treatments that saved their lives as children may trigger the development of heart abnormalities that might not cause apparent symptoms, the researchers explained. The investigators found that heart disease appears to affect between 3 percent and 24 percent of pediatric cancer survivors by the time they reach their 30s. Those figures rose to between 10 and 37 percent among patients 40 and older, the study found. However, while the study revealed a link between childhood cancer treatment and later heart disease, it didn't prove cause-and-effect. "The prevalence of these cardiac findings might be expected in an older adult population, but not necessarily in this young a population," said study lead author Dr. Daniel Mulrooney. ... Read more

Related support groups: Cancer, Methotrexate, Heart Disease, Fluorouracil, Xeloda, Cardiac Arrhythmia, Cardiomyopathy, Hydroxyurea, Left Ventricular Dysfunction, Mercaptopurine, Hydrea, Carboplatin, Cisplatin, Cytoxan, Dacogen, Temodar, Bendamustine, Cyclophosphamide, Oxaliplatin, Capecitabine

FDA Medwatch Alert: Adrucil (fluorouracil injection, USP) 5 g/100 mL (50 mg/mL) by Teva Parenteral Medicines: Recall - Particulate Matter

Posted 27 Jul 2015 by Drugs.com

[Posted 07/27/2015] ISSUE: Teva Parenteral Medicines announced a voluntary recall of six lots of Adrucil (fluorouracil injection, USP) 5 g/100 mL (50 mg/mL) due to the potential presence of particulate matter identified as aggregate of silicone rubber pieces from a filler diaphragm and fluorouracil crystals. Administration of an intravenous product with particulate matter has the potential to result in inflammation, allergic reactions, or blockage of blood vessels, leading to tissue death, which may be life-threatening if vital organs are affected. To date, Teva has not received any reports of adverse events related to this recall. See the press release for product lot numbers affected by this recall. BACKGROUND: Adrucil Injection is used in the palliative management of carcinoma of the colon, rectum, breast, stomach and pancreas and is packaged in pharmacy bulk packages. ... Read more

Related support groups: Cancer, Fluorouracil, Adrucil

U.S. Oncologists Decry High Cost of Cancer Drugs

Posted 23 Jul 2015 by Drugs.com

THURSDAY, July 23, 2015 – Soaring costs for cancer drugs are hurting patient care in the United States, a group of top oncologists claim. "High cancer-drug prices are affecting the care of patients with cancer and our health care system," Dr. Ayalew Tefferi, a hematologist at Mayo Clinic in Rochester, Minn., said in a Mayo news release. Tefferi and his colleagues made a number of recommendations on how to address the problem in a commentary published July 23 in the Mayo Clinic Proceedings. Allowing Medicare to negotiate drug prices is one of the suggestions the team of 118 leading cancer experts offered as a possible solution. Along with their recommendations, the group also expressed support for a patient-based grassroots movement on change.org that is demanding action on the issue. "The average gross household income in the U.S. is about $52,000 per year. For an insured patient with ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Breast Cancer, Accutane, Prostate Cancer, Lupron, Medroxyprogesterone, Tamoxifen, Arimidex, Tretinoin, Fluorouracil, Lupron Depot, Femara, Gleevec, Lung Cancer, Rituxan, Renal Cell Carcinoma, Isotretinoin

FDA Medwatch Alert: Adrucil (fluorouracil Injection, USP) 5 g/100 mL (50 mg/mL): Recall - Particulate Matter

Posted 5 May 2015 by Drugs.com

ISSUE: Teva Parenteral Medicines issued a voluntary recall of eight lots of Adrucil (fluorouracil injection, USP) 5 g/100 mL (50 mg/mL) due to the potential presence of particulate matter identified as aggregate of silicone rubber pieces from a filler diaphragm and fluorouracil crystals. See the press release for a listing of affected lot numbers. Administration of an intravenous product with particulate matter has the potential to result in inflammation, allergic reactions, or blockage of blood vessels, leading to tissue death, which may be life-threatening if vital organs are affected. BACKGROUND: Adrucil Injection is used in the palliative management of carcinoma of the colon, rectum, breast, stomach and pancreas and is packaged in pharmacy bulk packages. The pharmacy bulk package has five 5 g/100ml vials per shelf pack. Individual Adrucil 5 g/100 ml vials have the NDC code ... Read more

Related support groups: Cancer, Fluorouracil, Adrucil

Medicines Are Biggest Culprit in Fatal Allergic Reactions: Study

Posted 10 Oct 2014 by Drugs.com

THURSDAY, Oct. 9, 2014 – Although food allergies have garnered a lot of attention lately, a new study reports that medications are actually the biggest cause of sudden deaths related to allergy. Over a little more than a decade, nearly 60 percent of the allergy-related deaths were caused by medications, while less than 7 percent were caused by food allergies, the study found. "Medications can be dangerous," said study researcher Dr. Elina Jerschow, director of the Drug Allergy Center at Montefiore Medical Center and assistant professor of medicine at Albert Einstein College of Medicine, in New York City. While research from other countries has reported medications as a major culprit in anaphylaxis-related deaths, Jerschow said, the problem has been less defined in the United States. One reason is that there is no national registry for anaphylaxis deaths, she said. The study was ... Read more

Related support groups: Provera, Depo-Provera, Amoxicillin, Metronidazole, Doxycycline, Cephalexin, Clindamycin, Penicillin, Azithromycin, Methotrexate, Bactrim, Cipro, Ciprofloxacin, Accutane, Augmentin, Levaquin, Flagyl, Lupron, Keflex, Zithromax

Cancer Chemotherapy Tied to Slight Rise in Risk for Leukemia

Posted 14 Feb 2013 by Drugs.com

THURSDAY, Feb. 14 – Chemotherapy can be a lifesaver for thousands of cancer patients, but a new study suggests that it might slightly raise the odds for a type of leukemia later in life. Over the past 30 years, the risk for acute myeloid leukemia (AML) has increased for patients who underwent chemotherapy for certain forms of cancer, particularly non-Hodgkin lymphoma, the new study found. On the other hand, the researchers from the U.S. National Cancer Institute said other cancer survivors may have a reduced risk for AML due to a change in chemotherapy agents that occurred decades ago. One expert not connected to the study stressed that cancer patients need to put the findings into perspective. "It's important to realize that the risk of developing acute myeloid leukemia related to prior chemotherapy is small and increases with the number of chemotherapy treatments given over time," ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Accutane, Lupron, Medroxyprogesterone, Tamoxifen, Arimidex, Tretinoin, Fluorouracil, Lupron Depot, Femara, Gleevec, Rituxan, Isotretinoin, Claravis, Anastrozole, Votrient, Tarceva

'Uncertainty' Remains Over Supply of Key Cancer Drugs

Posted 4 Jun 2012 by Drugs.com

MONDAY, June 4 – John Mahan, a 58-year-old Nashville firefighter battling a gastrointestinal cancer, couldn't believe what he was hearing last July. His doctor had just told him that his clinic had run out of injectable fluorouracil (5-FU), the generic chemotherapy Mahan needed to keep his tumor at bay. "My initial reaction was, 'you've got to be kidding, right?'" he said. Unfortunately, the news was all too real. Mahan was switched to another drug, capecitabine. Taken in pill form, it had the same anti-cancer effectiveness as 5-FU but with more onerous side effects. "It made me feel bad, weak," Mahan said, "just run down, feeling tired all of the time, loss of appetite." At a Monday news briefing at the annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago, Mahan spoke on behalf of the thousands of cancer patients who have been hit hard by the recent nationwide ... Read more

Related support groups: Cancer, Methotrexate, Fluorouracil, Colorectal Cancer, Lymphoma, Xeloda, Taxol, Head and Neck Cancer, Capecitabine, Paclitaxel, Hodgkin's Lymphoma, Adrucil, Methotrexate LPF Sodium, Trexall, Folex PFS, Onxol, Rheumatrex Dose Pack

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