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Dealing With Diabetes Distress

Posted 16 Feb 2017 by Drugs.com

THURSDAY, Feb. 16, 2017 – People with diabetes have to think about their condition and make treatment decisions constantly – and all that extra work and worry can lead to psychological distress at times. "Diabetes distress" isn't the same as depression, however, diabetes experts note. It's a condition unique to the 24/7 demands that come with diabetes, particularly for people dependent on insulin. "The day you develop diabetes, it's like the universe just handed you a new full-time job that you have to do in addition to whatever else you're doing. It's a special job that has a big impact on the rest of your life. There's no pay and no vacation," said William Polonsky, president of the Behavioral Diabetes Institute in San Diego. Alicia McAuliffe-Fogarty, vice president of lifestyle management at the American Diabetes Association, put it this way: "Diabetes distress is the extra burden ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Lantus, Diabetes, Type 1, Glucophage, Glipizide, Novolog, Humalog, Insulin Resistance, Janumet, Glyburide, Invokana, Lantus Solostar, Levemir, Actos, Glimepiride, Pre-Diabetes, Novolin R, Amaryl

Insulin Makers Conspired to Raise Prices: Lawsuit

Posted 31 Jan 2017 by Drugs.com

Three makers of insulin conspired to boost the prices of the lifesaving diabetes drug, according to a lawsuit filed Monday in federal court in Massachusetts. A recent study in the Journal of the American Medical Association said the price of insulin nearly tripled between 2002 and 2013, and three manufacturers – Sanofi, Novo Nordisk and Eil Lilly – have raised the list prices of their insulin in near unison, The New York Times reported. The price increases have triggered anger among patient groups and doctors, who say the rising cost of insulin appears to have little to do with higher production costs. "People who have to pay out of pocket for insulin are paying enormous prices, when they shouldn't be," Steve Berman, a lawyer for the patients, told The Times. The lawsuits alleges that the three companies increased the list prices on their insulin in order to win favor with pharmacy ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Lantus, Diabetes, Type 1, Glucophage, Glipizide, Novolog, Humalog, Insulin Resistance, Janumet, Glyburide, Lantus Solostar, Levemir, Actos, Pre-Diabetes, Glimepiride, Novolin R, Amaryl, Novolin N

Diabetes Kills More Americans Than Had Been Thought

Posted 25 Jan 2017 by Drugs.com

WEDNESDAY, Jan. 25, 2017 – The number of Americans who die from diabetes is much higher than previously believed, according to a new study. The research, based on federal government data, found that diabetes causes 12 percent of deaths in the United States. That makes it the third-leading cause of death after heart disease and cancer, researchers said. "Another way of saying that is, if diabetes were eliminated as a disease process, the number of deaths would decline by 12 percent," said study author Samuel Preston, a sociology professor at the University of Pennsylvania. "There has been only one similar, earlier research effort, and it was based on data from the 1980s and early '90s. It showed deaths attributable to diabetes amounted to roughly 4 percent of total deaths," he said in a university news release. Data for the new study came from the U.S. National Health Interview Survey ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Heart Disease, Lantus, Glucophage, Glipizide, Novolog, Humalog, Insulin Resistance, Glyburide, Lantus Solostar, Levemir, Actos, Pre-Diabetes, Glimepiride, Novolin R, Amaryl, Novolin N, Pioglitazone

Language Barrier May Keep Some Hispanics From Good Diabetes Care

Posted 23 Jan 2017 by Drugs.com

MONDAY, Jan. 23, 2017 – Hispanic-American type 2 diabetes patients who lack proficiency in English may end up with poorer care, a new study finds. Specifically, these patients were found to be much less likely than non-Hispanic patients to take newly prescribed diabetes medications as directed, the researchers said. The study "suggests that more needs to be done to improve adherence to newly prescribed medications among Latino patients at all levels of English proficiency," wrote a team led by Dr. Alicia Fernandez, of the University of California, San Francisco. A diabetes specialist who reviewed the study wasn't surprised by the results. The research "further validates what many clinicians already know: Patients who do not understand English tend to do worse with management of chronic disease," said Dr. Maria Pena. She is an endocrinologist who directs the Center for Weight Management ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Lantus, Diabetes, Type 1, Glucophage, Novolog, Glipizide, Humalog, Janumet, Insulin Resistance, Glyburide, Invokana, Lantus Solostar, Levemir, Actos, Pre-Diabetes, Glimepiride, Novolin R, Amaryl

Metformin Still Best Choice for First Type 2 Diabetes Treatment

Posted 3 Jan 2017 by Drugs.com

MONDAY, Jan. 2, 2017 – Newly updated guidelines reaffirm that metformin is the first-line drug for people with type 2 diabetes, and that several other medications – including newer ones – can be added if needed. The recommendations come from the American College of Physicians (ACP). The American Academy of Family Physicians endorsed the new guidelines. The ACP updated the guidelines because of new research into diabetes drugs, and the U.S. Food and Drug Administration approval of new diabetes drugs. "Metformin, unless contraindicated, is an effective treatment strategy because it has better effectiveness, is associated with fewer adverse effects, and is cheaper than most other oral medications," ACP president Dr. Nitin Damle said in a college news release. "The escalating rates of obesity in the U.S. are increasing the incidence and prevalence of diabetes substantially. Metformin has ... Read more

Related support groups: Diabetes, Type 2, Metformin, Januvia, Glucophage, Glipizide, Janumet, Glyburide, Invokana, Actos, Glimepiride, Pre-Diabetes, Amaryl, Pioglitazone, Tradjenta, Avandia, Glucophage XR, GlipiZIDE XL, Farxiga, Glucotrol, Jardiance

FDA Medwatch Alert: Pioglitazone-containing Medicines: Drug Safety Communication - Updated FDA Review, Increased Risk of Bladder Cancer

Posted 13 Dec 2016 by Drugs.com

ISSUE: As a result of an updated review, the FDA has concluded that use of the type 2 diabetes medicine pioglitazone (Actos, Actoplus Met, Actoplus Met XR, Duetact, Oseni) may be linked to an increased risk of bladder cancer. The labels of pioglitazone-containing medicines already contain warnings about this risk, and FDA has approved label updates to describe the additional studies reviewed. See the FDA Drug Safety Communication for more details, including a data summary. BACKGROUND: FDA alerted the public about the possible risk of bladder cancer in September 2010 and June 2011 based on interim results from a 10-year epidemiologic study. FDA changed the labels of pioglitazone-containing medicines in August 2011 to include warnings about this risk, and required the manufacturer to modify and continue the 10-year study. Pioglitazone is approved to improve blood sugar control, along with ... Read more

Related support groups: Diabetes, Type 2, Actos, Pioglitazone, ActoPlus Met, Metformin/Pioglitazone, Oseni, Alogliptin/pioglitazone, Glimepiride/Pioglitazone, ActosPlus Met, Duetact

Have Type 2 Diabetes? Try Walking After Eating

Posted 18 Oct 2016 by Drugs.com

TUESDAY, Oct. 18, 2016 – For people with type 2 diabetes, a short walk after eating may help lower blood sugar levels more than exercising at other times of the day, a new study shows. A measurement of blood sugar called postprandial glycemia, which has been linked with heart disease risk, averaged 12 percent lower when study participants took a walk after eating, compared with those who exercised at other times. The largest drop in postprandial glycemia, 22 percent, was achieved by walking after dinner, the study authors found. "If you have type 2 diabetes, there is a guideline to be active for at least 150 minutes a week," said study author Andrew Reynolds, a researcher at the University of Otago, in New Zealand. But, he added, "the benefits we observed due to physical activity after meals suggest that current guidelines should be amended to specify after-meal activity, particularly ... Read more

Related support groups: Diabetes, Type 2, Heart Disease, Glipizide, Insulin Resistance, Glyburide, Invokana, Actos, Glimepiride, Pre-Diabetes, Amaryl, Pioglitazone, Diabetes Mellitus, Avandia, GlipiZIDE XL, Farxiga, Glucotrol, Jardiance, Acarbose, Glucotrol XL, Ischemic Heart Disease

Intensive Type 2 Diabetes Treatment Can Extend Survival: Study

Posted 8 Sep 2016 by Drugs.com

WEDNESDAY, Sept. 7, 2016 – Intensive management of type 2 diabetes can make a difference in how long and how well you live, even if you don't start until middle age, researchers report. People who were already at risk of type 2 diabetes complications were randomly selected to continue with their normal treatment or to be placed in an aggressive and multipronged treatment group. Two decades after the study began, the researchers found that people in the aggressive treatment group lived almost eight years longer. Not only that, they lived better – their risk of heart disease, kidney disease and blindness all dropped. The only complication that didn't seem to improve was nerve damage caused by diabetes. "Early, intensified intervention in type 2 diabetes patients with microalbuminuria with both target-driven pharmacological (medication) and behavioral actions increased life span. And, ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Victoza, Lantus, Januvia, Glucophage, Novolog, Glipizide, Saxenda, Humalog, Janumet, Byetta, Glyburide, Bydureon, Invokana, Lantus Solostar, Levemir, Actos, Trulicity

Intensive Blood Sugar Control May Be Too Much for Some With Type 2 Diabetes

Posted 6 Jun 2016 by Drugs.com

MONDAY, June 6, 2016 – Intensive treatment of blood sugar levels in some people with type 2 diabetes may cause serious complications, new research suggests. "In this study, we found that, particularly among older patients and patients with serious chronic conditions, intensive treatment nearly doubled the risk of severe hypoglycemia requiring medical attention, including hospitalization," said lead author Dr. Rozalina McCoy. She is an endocrinologist at the Mayo Clinic in Rochester, Minn. Hypoglycemia (low blood sugar) is a serious potential complication of diabetes treatment. The researchers said it can worsen quality of life and has been linked with cardiovascular events, dementia and death. The researchers reviewed information from more than 31,500 American adults. All had stable and controlled type 2 diabetes. None was taking insulin. None had a prior history of severe ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Lantus, Dementia, Glucophage, Glipizide, Novolog, Humalog, Hypoglycemia, Janumet, Glyburide, Invokana, Lantus Solostar, Levemir, Actos, Glimepiride, Novolin R, Amaryl, Novolin N

Cost of Insulin Rises Threefold in Just a Decade: Study

Posted 5 Apr 2016 by Drugs.com

TUESDAY, April 5, 2016 – Americans with diabetes who rely on insulin to keep their blood sugar levels in check are facing sticker shock: A new study finds the price of insulin has tripled in only 10 years. Moreover, since 2010, per-person spending on insulin in the United States was more than spending on all other diabetes drugs, the study found. "The cost of insulin has risen rapidly over the last few years," said study senior author Philip Clarke, a professor of health economics at the University of Melbourne in Australia. Clarke added there should be an assessment to see whether this price hike is justifiable in terms of improved clinical outcomes. One reason for the price climb, he said, is a switch from human insulins to analog insulins, which cost more but may offer additional benefits. Also, doctors are more apt to prescribe insulin for people with type 2 diabetes now, Clarke ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Victoza, Lantus, Diabetes, Type 1, Januvia, Glucophage, Diabetic Neuropathy, Glipizide, Novolog, Saxenda, Humalog, Insulin Resistance, Janumet, Diabetic Nerve Damage, Byetta, Glyburide, Bydureon, Invokana

Diabetes Meds Vary in Safety and Effectiveness, Study Shows

Posted 31 Mar 2016 by Drugs.com

THURSDAY, March 31, 2016 – A study of nearly a half-million people with type 2 diabetes shows there are pros and cons to nearly every form of drug therapy for the disease. In the British study, researchers looked at patient outcomes from a large U.K. database of almost 470,000 adults with type 2 diabetes, tracked between 2007 and 2015. Julia Hippisley-Cox and Carol Coupland, of the University of Nottingham, sought to parse out differences among a variety of diabetes drugs. They accounted for complicating patient factors such as age, sex, smoking and poverty, as well as how long a person had been diagnosed with type 2 diabetes. The researchers also focused on five major outcomes linked to diabetes: blindness, amputation, severe kidney failure, and high or low blood sugar. Reporting March 30 in BMJ, they found that when a class of drugs called glitazones (Actos, Avandia) was prescribed ... Read more

Related support groups: Diabetes, Type 2, Metformin, Glucophage, Glipizide, Janumet, Insulin Resistance, Glyburide, Actos, Glimepiride, Pre-Diabetes, Amaryl, Diabetes Mellitus, Avandia, Glucophage XR, Prandin, GlipiZIDE XL, Glucotrol, ActoPlus Met, Glucotrol XL, Glumetza

More Evidence Diabetes Drug Actos Raises Bladder Cancer Risk a Bit

Posted 31 Mar 2016 by Drugs.com

WEDNESDAY, March 30, 2016 – More evidence linking the diabetes drug Actos to an increased risk of bladder cancer has surfaced in a new study that also finds the risk rises with increased use. Actos (pioglitazone) appears to increase risk of bladder cancer by 63 percent, Canadian researchers say. The findings, published March 30 in The BMJ, stem from an analysis of nearly 146,000 patients treated between 2000 and 2013. The data also showed that bladder cancer risk increases if Actos is used for more than two years, or if someone takes more than 28,000 milligrams over the course of their lives. The overall risk is small, however. Still, "the more you accumulate the drug into your system, the higher the risk," said senior researcher Laurent Azoulay, an associate professor of oncology at McGill University in Montreal. Azoulay and his colleagues did not find a similar link between bladder ... Read more

Related support groups: Diabetes, Type 2, Insulin Resistance, Actos, Pre-Diabetes, Pioglitazone, Diabetes Mellitus, Bladder Cancer, Avandia, ActoPlus Met, Avandamet, Abnormal Glucose Tolerance, Rosiglitazone, Metformin/Pioglitazone, Oseni, Alogliptin/pioglitazone, Glimepiride/Pioglitazone, ActosPlus Met, Avandaryl, Glimepiride/Rosiglitazone, Duetact

Diabetes Drug May Help Prevent Second Stroke: Study

Posted 18 Feb 2016 by Drugs.com

WEDNESDAY, Feb. 17, 2016 – The diabetes drug Actos (pioglitazone) appears to protect people who've already had a stroke from suffering a second stroke, a new study finds. Along with standard treatment after a stroke – including blood thinners, and blood pressure and cholesterol medication – the addition of Actos reduced the odds of another stroke by 24 percent compared to a placebo, the researchers said. "Actos represents a new option for patients who have had a stroke to help prevent a future stroke," said lead researcher Dr. Walter Kernan, a professor of medicine at Yale School of Medicine in New Haven, Conn. For the study, Kernan and colleagues randomly assigned nearly 4,000 patients who had suffered a stroke or a mini-stroke to Actos or a placebo. None of the patients had diabetes but they did have evidence of insulin resistance, putting them at risk for the blood-sugar disease. ... Read more

Related support groups: Diabetes, Type 2, Insulin, Ischemic Stroke, Transient Ischemic Attack, Actos, Pioglitazone, Diabetes Mellitus, Ischemic Stroke - Prophylaxis, ActoPlus Met, Intracranial Hemorrhage, Metformin/Pioglitazone, Oseni, Alogliptin/pioglitazone, Glimepiride/Pioglitazone, ActosPlus Met, Duetact

New Diabetes Cases Among Americans Drop for First Time in Decades: CDC

Posted 1 Dec 2015 by Drugs.com

TUESDAY, Dec. 1, 2015 – In a sign that Americans may finally be turning the corner in the fight against diabetes – and possibly obesity – federal health statistics released Tuesday show that the number of new cases of diabetes has dropped for the first time in decades. The decline wasn't sudden or dramatic. But, the number of new diabetes cases went from 1.7 million in 2009 to 1.4 million in 2014, according to the U.S. Centers for Disease Control and Prevention. "It seems pretty clear that incidence rates have now actually started to drop. Initially it was a little surprising because I had become so used to seeing increases everywhere we looked," CDC researcher Edward Gregg told The New York Times. The proportion of Americans with diabetes is still twice what it was in the early 1990s. And not every racial group has made strides against the blood sugar disease, which is often ... Read more

Related support groups: Obesity, Diabetes, Type 2, Metformin, Insulin, Weight Loss, Victoza, Lantus, Januvia, Glucophage, Glipizide, Novolog, Saxenda, Humalog, Janumet, Glyburide, Byetta, Bydureon, Invokana, Lantus Solostar, Levemir

Type 2 Diabetes Drug Helps Some With Chronic Depression: Study

Posted 18 Nov 2015 by Drugs.com

WEDNESDAY, Nov. 18, 2015 – A new small study is adding evidence to the theory that insulin resistance may play a leading role in some people's depression. The study found that a medication normally used to boost insulin sensitivity in people with type 2 diabetes appears to help ease the symptoms of chronic depression. And, the effect was strongest in people who were insulin-resistant but didn't have diabetes, the study found. These findings "add to the neurobiological explanation of what's going on when people are depressed, and it should help de-stigmatize depression. It's a disease of the brain," said the study's lead author, Dr. Natalie Rasgon, a professor of psychiatry and behavioral sciences at Stanford University School of Medicine in California. "Depression is kind of a catch-all term, like the common cold; it can have more than one cause," Rasgon said. "In this study, we saw ... Read more

Related support groups: Depression, Diabetes, Type 2, Major Depressive Disorder, Postpartum Depression, Insulin Resistance, Actos, Dysthymia, Seasonal Affective Disorder, Pioglitazone, ActoPlus Met, Depressive Psychosis, Metformin/Pioglitazone, Oseni, Glimepiride/Pioglitazone, Alogliptin/pioglitazone, ActosPlus Met, Duetact

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