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Bone Drug 'Holiday' From Bisphosphonates May Raise Fracture Risk

Posted 11 May 2018 by Drugs.com

FRIDAY, May 11, 2018 – Osteoporosis patients who take "holidays" from bisphosphonate drugs are at increased risk for fractures, a new study finds. A six-year follow-up of patients who took a break from the bone-building drugs found 15 percent of them suffered fractures, according to researchers at Loyola University in Maywood, Ill. "Fracture risk needs to be regularly assessed during the drug ...

Growth Hormone May Lower Odds of Fractures in Older Women

Posted 27 Aug 2015 by Drugs.com

THURSDAY, Aug. 27, 2015 – Older women with osteoporosis could get lasting benefits from a few years on growth hormone, a new, small trial suggests. Researchers found that when women with the bone-thinning disease took growth hormone for three years, their fracture risk was still reduced seven years later. Before entering the study, 56 percent of the women had suffered a bone break; over the ...

Certain Generic Meds May Help Older Patients With Early Breast Cancer

Posted 23 Jul 2015 by Drugs.com

THURSDAY, July 23, 2015 – There's more evidence that two classes of inexpensive generic drugs reduce the risk of death in postmenopausal women with early breast cancer, a pair of new British studies find. The two classes of drugs – called aromatase inhibitors and bisphosphonates – can also be used together to increase the benefits and reduce some side effects, according to the authors of the ...

Strong Bones After 50? Women May Not Need Next Test Until 65

Posted 9 Jun 2015 by Drugs.com

TUESDAY, June 9, 2015 – A postmenopausal woman who is 50 and still shows "normal" readings on her bone density test may not need her next such test for 10 or even 15 years, a new study finds. However, researchers led by Dr. Margaret Gourlay of the University of North Carolina at Chapel Hill stressed that younger women who do show signs of bone loss are at high risk for a major fracture, and do ...

Too Many Women Who Need Bone Screening Aren't Getting It

Posted 25 May 2015 by Drugs.com

MONDAY, May 25, 2015 – Too few women at high risk for osteoporosis are being tested for the bone-depleting condition, while too many women at low-risk are being screened, a new study suggests. A team led by Dr. Anna Lee Amarnath of the University of California, Davis, examined the medical records of nearly 51,000 women, aged 40 to 85, living in the Sacramento area. The researchers looked at ...

Bone Drugs May Protect Against Endometrial Cancer

Posted 22 Dec 2014 by Drugs.com

MONDAY, Dec. 22, 2014 – Bisphosphonates, which are drugs that treat bone loss, may lower the risk of endometrial cancer, new research suggests. The study found that women taking the drugs had about half the risk of endometrial cancer compared to women who don't take the drugs. Endometrial cancer – one of the most common types of cancer in women – affects the lining of the uterus. ...

Too Few Prostate Cancer Patients Get Bone-Strengthening Meds: Study

Posted 3 Dec 2014 by Drugs.com

TUESDAY, Dec. 2, 2014 – Many men on hormone therapy for prostate cancer aren't getting bone-strengthening drugs they may need, new Canadian research contends. Hormone therapy, which suppresses male hormones called androgens, helps stop cancer cells from growing. But one consequence of the treatment is weakening of the bones, which can lead to fractures. To reduce this risk, men can be given oral ...

Osteoporosis Drugs Work, But Review Finds No Clear Winner

Posted 8 Sep 2014 by Drugs.com

MONDAY, Sept. 8, 2014 – Many osteoporosis drugs cut women's risk of suffering a bone fracture, though it's not clear whether any one medication works better than others, a new research review finds. Reporting Sept. 8 in Annals of Internal Medicine, researchers said that for women with the bone-thinning disease osteoporosis, various drugs cut the risk of a spine fracture by 40 to 60 percent, ...

More Evidence Ties Some Bone-Building Drugs to Rare Fractures

Posted 4 Sep 2014 by Drugs.com

THURSDAY, Sept. 4, 2014 – Taking osteoporosis drugs called bisphosphonates to help prevent fractures may carry a slight risk for unusual breaks in the thigh bone, Swedish researchers report. For those who took bisphosphonates for four to five years, the so-called "relative risk" was 100 times higher than among people who didn't use the medications. But the researchers explained that the absolute ...

Bone Drugs Don't Lower Breast Cancer Risk After All, Study Finds

Posted 11 Aug 2014 by Drugs.com

MONDAY, Aug. 11 – Drugs known as bisphosphonates, commonly prescribed to treat the bone-weakening disease osteoporosis, don't appear to reduce the risk of breast cancer as previously thought, new research finds. "We found that postmenopausal women who took a bisphosphonate for three or four years did not have a decreased risk in breast cancer," said study author Trisha Hue, an epidemiologist at ...

FDA Medwatch Alert: Oral Osteoporosis Drugs (bisphosphonates): Drug Safety Communication - Potential Increased Risk of Esophageal Cancer

Posted 21 Jul 2011 by Drugs.com

Includes: Fosamax (alendronate), Actonel (risedronate), Boniva (ibandronate), Atelvia (risedronate delayed release), Didronel (etidronate), and Skelid (tiludronate) ISSUE: FDA notified healthcare professionals and patients about its ongoing review of data from published studies to evaluate whether use of oral bisphosphonate drugs is associated with an increased risk of cancer of the esophagus. ...

FDA Medwatch Alert: Update on Early Communication: Bisphosphonates marketed as Alendronate (Fosamax, Fosamax Plus D); Etidronate (Didronel); Ibandronate (Boniva); Pamidronate (Aredia); Risedronate (Actonel, Actonel W/Calcium); Tiludronate (Skelid); Zoledronic acid (Recl

Posted 12 Nov 2008 by Drugs.com

[Posted 11/12/2008] FDA issued an update to the Agency's review of safety data regarding the potential increased risk of atrial fibrillation in patients treated with a bisphosphonate drug. Bisphosphonates are a class of drugs used primarily to increase bone mass and reduce the risk for fracture in patients with osteoporosis, slow bone turnover in patients with Paget’s disease of the bone, ...

FDA Medwatch Alert: Bisphosphonates (marketed as Actonel, Actonel+Ca, Aredia, Boniva, Didronel, Fosamax, Fosamax+D, Reclast, Skelid, and Zometa)

Posted 7 Jan 2008 by Drugs.com

[Posted 01/07/2008] FDA informed healthcare professionals and patients of the possibility of severe and sometimes incapacitating bone, joint, and/or muscle (musculoskeletal) pain in patients taking bisphosphonates. Although severe musculoskeletal pain is included in the prescribing information for all bisphosphonates, the association between bisphosphonates and severe musculoskeletal pain may be ...

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Related Condition Support Groups

Prevention of Osteoporosis, Osteoporosis, Paget's Disease

Actonel Patient Information at Drugs.com