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Acetaminophen Overdose News

Related terms: Acetaminophen Toxicity

How Older People Can Head Off Dangerous Drug Interactions

Posted 25 Sep 2016 by Drugs.com

SATURDAY, Sept. 24, 2016 – Potentially serious drug interactions are a daily threat to older people who take multiple medications and supplements, according to the U.S. Food and Drug Administration. One drug can affect the effectiveness of other drugs and how your body uses them. For example, your kidney and liver may not work as well, which affects how drugs are broken down and leave your body, the FDA said. "There is no question that physiology changes as we age. Many chronic medical conditions don't even appear until our later years," Dr. Sandra Kweder, an FDA medical officer, said in an agency news release. "It's not that people are falling to pieces; some changes are just part of the normal aging process." The FDA says these safety tips will help prevent harmful drug interactions or side effects: Follow your doctor's directions. You shouldn't take drugs that your doctor doesn't ... Read more

Related support groups: Allergic Reactions, Poisoning, Toxic Reactions Incl Drug and Substance Abuse, Acetaminophen Overdose, Digitalis Glycoside Toxicity

Dosing Errors Common With Kids' Liquid Meds

Posted 12 Sep 2016 by Drugs.com

MONDAY, Sept. 12, 2016 – Parents may give their child too much or too little medicine when dispensing liquid medication, especially if they use a dosing cup, a new study reports. Four out of five parents made at least one dosing error when using either a dosing cup or an oral syringe, researchers found during laboratory experiments. Often, those errors were large enough to cause concern, said lead researcher Dr. Shonna Yin, an associate professor of pediatrics at NYU School of Medicine in New York City. "Over 20 percent of parents made at least one dosing error that was more than two times the dose that was listed on the label," Yin said. Dosing cups proved much less reliable than an oral syringe in terms of dosage, the research revealed. "Parents had four times the odds of making an error with a cup compared with a syringe," Yin said. These errors could result in a child receiving an ... Read more

Related support groups: Toxic Reactions Incl Drug and Substance Abuse, Acetaminophen Overdose

FDA Medwatch Alert: Cetylev (acetylcysteine) Effervescent Tablets for Oral Solution: Recall - Inadequate Seal of Blister Pack

Posted 18 Aug 2016 by Drugs.com

ISSUE: Arbor  Pharmaceuticals, LLC announced a voluntary recall of three (3) lots of Cetylev (acetylcysteine) effervescent tablets for oral solution, 500 mg, due to an inadequate seal of the blister pack. An inadequate seal could result in an increase of oxygen and moisture entering the blister cavity which can start the effervescent process. This results in enlarged and swelled tablets which could also completely dissolve within the blister pack. The improper seal of the product can lead to a potentially sub-therapeutic dose as well as potential microbial contamination. Because the effectiveness of acetylcysteine to prevent or lessen hepatic injury after ingestion of acetaminophen is delayed with decreased therapy, sub-therapeutic dosing could lead to increased risk of liver injury. With regards to the potential microbial contamination due to moisture ingress into the tablets, the risk ... Read more

Related support groups: Acetylcysteine, Acetaminophen Overdose, Cetylev

60,000 U.S. Kids Treated for Accidental Medicine Poisoning a Year

Posted 21 Mar 2016 by Drugs.com

MONDAY, March 21, 2016 – Nearly 60,000 children in the United States are accidentally poisoned by medicines each year, a new report says. That's the equivalent of four busloads of children – or one every nine minutes – arriving at emergency departments every day because of medicine-related poisoning, according to Safe Kids Worldwide. And nearly every minute each day a poison control center receives a call about a child who got into medicines, the report notes. "We want parents and caregivers to remember that the first line of defense in preventing medicine poisoning is the family," Kate Carr, president and CEO of Safe Kids Worldwide, said in a news release from the group. Americans fill nearly three times as many prescriptions as they did in 1980 and spend five times as much on over-the-counter drugs, according to the report. With so many medications on hand, parents and other adults ... Read more

Related support groups: Poisoning, Toxic Reactions Incl Drug and Substance Abuse, Lead Poisoning, Acetaminophen Overdose, Iron Poisoning, Mercury Poisoning

Arbor Pharmaceuticals Announces FDA Approval of Cetylev

Posted 18 Feb 2016 by Drugs.com

Atlanta, GA, February 9, 2016 – Arbor Pharmaceuticals announced today that the U.S. Food and Drug Administration (FDA) approved its New Drug Application (NDA) for Cetylev (acetylcysteine effervescent tablets for oral solution). Cetylev is an antidote for acetaminophen overdose indicated to prevent or lessen hepatic injury after ingestion of a potentially hepatotoxic quantity of acetaminophen in patients with acute ingestion or from repeated supratherapeutic ingestion. Acetaminophen overdose is the most common poisoning reported to emergency rooms in the United States. According to the American Association of Poison Control Centers there were 73,347 reported acetaminophen exposures in 2014 which resulted in 108 deaths. Cetylev will be available in ready to use effervescent tablets intended to be mixed with water, resulting in a pleasant lemon-mint tasting solution. Currently, ... Read more

Related support groups: Acetaminophen, Acetylcysteine, Acetaminophen Overdose, Cetylev

Kids' ER Visits for Medicine Overdoses Dropping: Report

Posted 8 Sep 2015 by Drugs.com

TUESDAY, Sept. 8, 2015 – Fewer children are winding up in emergency rooms for accidental poisonings involving commonly used medications, a new U.S. government study finds. "We think these declines are real," said lead researcher Maribeth Lovegrove, of the U.S. Centers for Disease Control and Prevention's division of healthcare quality promotion. Between 2004 and 2013, approximately 640,000 children aged 5 and younger were seen in emergency rooms for ingesting drugs. Of these, 70 percent were 1- or 2-year-olds, and nearly one in five were hospitalized, according to the report. The number of pediatric emergency room visits rose during the early 2000s, peaking at approximately 76,000 in 2010, but declined to approximately 59,000 visits in 2013, Lovegrove said. While there has been a decline in emergency room visits, 59,000 visits a year for young children is still too many, Lovegrove ... Read more

Related support groups: Xanax, Suboxone, Oxycodone, Hydrocodone, Methadone, Percocet, Tramadol, OxyContin, Klonopin, Vicodin, Cough, Norco, Fentanyl, Clonazepam, Morphine, Ativan, Valium, Codeine, Lortab, Tylenol

Milliliter-Only Dosing Recommended for Kids' Meds

Posted 30 Mar 2015 by Drugs.com

MONDAY, March 30, 2015 – Time to toss out the teaspoon and tablespoon when it comes to sick kids: The best way to measure liquid medications for children is in metric milliliters, a leading group of U.S. pediatricians says. "Metric dosing is the most precise way to dose medications and prevent overdoses," said Dr. Ian Paul, lead author of a new policy statement from the American Academy of Pediatrics. Accidental medication overdoses send more than 70,000 children to U.S. emergency rooms each year, according to background information with the statement, which is published online March 30 in the journal Pediatrics. Two common ways these overdoses occur are incorrect measurement of the medicine and using the wrong device to measure it out – giving a tablespoon instead of a teaspoon, for instance. "There are increasing data that suggest that some dosing errors and overdoses occur when ... Read more

Related support groups: Poisoning, Acetaminophen Overdose

FDA Warns Against Prescription Drugs With High Levels of Acetaminophen

Posted 15 Jan 2014 by Drugs.com

WEDNESDAY, Jan. 15, 2014 – The U.S. Food and Drug Administration has asked doctors to stop prescribing painkillers that contain more than 325 milligrams of acetaminophen because of reports of severe liver damage. Prescription painkillers, which include Vicodin and Percocet, are commonly given for pain following acute injuries, operations or dental procedures and they often contain acetaminophen. However, many over-the-counter medications also contain acetaminophen. The FDA first tackled this issue in January 2011, when it asked drug makers to stop making prescription painkillers that contained more than 325 milligrams of acetaminophen per dose. Accidental overdoses from using these products contributes to nearly half of all cases of acetaminophen-related liver failure in the United States, the agency said in a statement issued Tuesday. Most cases of severe liver injury occurred in ... Read more

Related support groups: Percocet, Vicodin, Norco, Lortab, Tylenol, Acetaminophen, Paracetamol, Fioricet, Excedrin, Endocet, Darvocet-N 100, Tylenol PM, NyQuil, Acetaminophen/Hydrocodone, Tylenol with Codeine, Percocet 10/325, Ultracet, Tylenol with Codeine 3, DayQuil, Daytime

Tylenol-Induced Liver Failure Presents Own Set of Problems: Study

Posted 19 Jul 2013 by Drugs.com

WEDNESDAY, July 17 – People with liver failure caused by an overdose of acetaminophen (Tylenol) have poorer health than patients whose liver failure was caused by other problems, a new study finds. They reported more days of poor mental and physical health, activity limitations because of poor health, pain, anxiety and depression than other liver failure patients, U.S. researchers found. Acetaminophen-overdose patients also had higher rates of substance abuse and psychiatric disease than other liver failure patients, the study found. And patients who suffered an accidental acetaminophen overdose were less likely to have psychiatric disorders than those who intentionally overdosed, 48 percent versus 82 percent. For the study, published online in the journal Liver Transplantation, the researchers analyzed data from more than 280 patients who were diagnosed with acute liver failure ... Read more

Related support groups: Vicodin, Norco, Lortab, Tylenol, Acetaminophen, Paracetamol, Fioricet, Excedrin, Darvocet-N 100, Tylenol PM, NyQuil, Acetaminophen/Hydrocodone, Tylenol with Codeine, Ultracet, Tylenol with Codeine 3, DayQuil, Daytime, Coricidin, Panadol, Acetaminophen/Oxycodone

Many Americans Taking Too Much Acetaminophen

Posted 2 Jun 2012 by Drugs.com

FRIDAY, June 1 – Many U.S. adults are at risk for overdosing on over-the-counter pain relievers containing acetaminophen, according to a new study. Acetaminophen (Tylenol) is the most commonly used over-the-counter pain medication in the United States, and acetaminophen overdose is the leading cause of acute liver failure, according to researchers from Northwestern University in Evanston, Ill.. The researchers interviewed 500 adult patients at outpatient general medicine clinics in Atlanta and Chicago. More than half had used acetaminophen in the past six months and 19 percent said they were heavy users, which means they took acetaminophen every day or a couple of times a week. The study authors then assessed whether the patients understood the recommended dosage of acetaminophen products and if they were able to take them safely. The results showed that nearly a quarter of the ... Read more

Related support groups: Percocet, Vicodin, Norco, Lortab, Tylenol, Acetaminophen, Paracetamol, Fioricet, Excedrin, Endocet, Tylenol PM, Darvocet-N 100, NyQuil, Acetaminophen/Hydrocodone, Tylenol with Codeine, Percocet 10/325, Ultracet, Tylenol with Codeine 3, DayQuil, Daytime

Patients May Receive Too Much Acetaminophen in Hospital

Posted 23 May 2012 by Drugs.com

WEDNESDAY, May 23 – Roughly 2.5 percent of admitted hospital patients may receive more than the safe daily cumulative dose of the pain-reliever acetaminophen, best known as Tylenol, on at least one day, according to a new U.S. study. Patients on more than one drug containing acetaminophen often consume more than the recommended 4 grams per day of the drug, the researchers from Thomas Jefferson University Hospital in Philadelphia found. Together, two tablets of extra-strength Tylenol contain 1 gram of acetaminophen, commonly used to relieve pain and reduce fever. Over the course of two years, researchers led by Dr. Jesse Civan examined 46,000 hospital admissions and the medications those patients were given. They found that on at least one day of hospitalization, roughly 1,100 patients received more than 4 grams of acetaminophen in the form of Tylenol, Percocet and similar drugs. The ... Read more

Related support groups: Percocet, Vicodin, Norco, Lortab, Tylenol, Acetaminophen, Paracetamol, Fioricet, Excedrin, Endocet, Tylenol PM, Darvocet-N 100, NyQuil, Acetaminophen/Hydrocodone, Tylenol with Codeine, Percocet 10/325, Ultracet, Tylenol with Codeine 3, DayQuil, Daytime

IV Acetaminophen Linked to More Child Overdoses

Posted 27 Jan 2012 by Drugs.com

FRIDAY, Jan. 27 – Following the U.S. Food Drug Administration's approval last year of an intravenous formulation of acetaminophen for fever and pain in a hospital setting, researchers warn that use of the preparation could lead to serious overdoses, particularly among the youngest patients. The problem: There is confusion over measurement guidelines – milligrams vs. milliliters, to be specific – that can result in the accidental administration of doses that are up to 10 times more than the proper amount. "This product would be given in a health care facility," said study co-author Dr. Richard Dart, from the Rocky Mountain Poison and Drug Center at Denver Health in Colorado. "And thus, the overdose ends up being from a miscalculation by a health care provider." "In theory, the risk to the child is that they could develop serious liver injury," Dart added. "Liver injury is avoided if ... Read more

Related support groups: Tylenol, Acetaminophen, Paracetamol, Panadol, Paracetamol Teva, Tylenol Extra Strength, Tylenol Arthritis Caplet, Q-Pap, Panadol Osteo, Childrens Tylenol, Lemsip Max, Acetaminophen Quickmelt, Perfalgan, Acetaminophen Overdose, Panamax, Q-Pap Extra Strength, Aceta, Altenol, Doliprane, Q-Nol

Too Much Acetaminophen Over Time May Damage Liver

Posted 22 Nov 2011 by Drugs.com

TUESDAY, Nov. 22 – Taking slightly too much of the pain reliever acetaminophen (best known by the brand name Tylenol) over time can lead to an overdose that can cause liver failure and death, according to a new study. These "staggered overdoses" can occur when people have ongoing pain and repeatedly take a little more acetaminophen than they should, explained Dr. Kenneth Simpson, author of the study, published Nov. 22 in the British Journal of Clinical Pharmacology. "They haven't taken the sort of single-moment, one-off massive overdoses taken by people who try to commit suicide, but over time the damage builds up, and the effect can be fatal," Simpson said in a journal news release. He and his colleagues analyzed data from 663 patients with acetaminophen-induced liver injury who were admitted to the Royal Infirmary of Edinburgh, Scotland between 1992 and 2008. In the U.K. and ... Read more

Related support groups: Percocet, Vicodin, Norco, Lortab, Tylenol, Acetaminophen, Paracetamol, Fioricet, Excedrin, Endocet, Tylenol PM, Darvocet-N 100, NyQuil, Acetaminophen/Hydrocodone, Tylenol with Codeine, Percocet 10/325, Ultracet, Tylenol with Codeine 3, DayQuil, Roxicet

Poison Experts Turn Phone Line Into a Lifeline

Posted 19 Sep 2010 by Drugs.com

FRIDAY, Sept. 17 – Trained as a registered nurse to work in emergency rooms and intensive care units, Hugh Rawls did just that until sidelined a decade ago by a back injury. Today, he's still working in emergency care, but from a different angle. For the past 10 years, he has helped man the phone lines at the Poison Control Center in Jacksonville, Fla. "In a lot of ways, there's some similarities in the critical thinking I used as a bedside nurse," said Rawls, 45. "Part of my job is not only to think about what's going on right now, but also to think three steps ahead to what could happen. I have to think ahead as to what could happen to this person and where we need to go treatment-wise." People call the center with a wide variety of problems, Rawls said. "This is very similar to working in an emergency room," he said. "You don't know what's going to come up next. One minute it's a ... Read more

Related support groups: Ethylene Glycol Poisoning, Acetaminophen Overdose, Arsenic Poisoning, Organophosphate Poisoning, Cyanide Poisoning, Lead Poisoning, Anticholinesterase Poisoning, Arsenic Poisoning - Severe, Iron Poisoning, Acute Alcohol Intoxication, Lead Poisoning - Mild, Benzodiazepine Overdose, Methanol Poisoning, Gold Poisoning - Severe, Iron Poisoning - Chronic, Digitalis Glycoside Toxicity, Lead Poisoning - Severe, Arsenic Poisoning - Mild, Gold Poisoning - Mild, Iron Poisoning - Acute

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acetylcysteine, Mucomyst, NAC, Parvolex, Mucomyst-10, Mucomyst-20, Cetylev, Acys-5, Acetadote, Solgar NAC