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Taking Your Meds? A Digital Pill Can Tell

Posted 9 days ago by Drugs.com

MONDAY, Dec. 4, 2017 – Pairing medication with an ingestible sensor can help clinicians track how often and when patients actually take their prescription drugs, according to a small new investigational study. The findings come on the heels of the U.S. Food and Drug Administration's decision last month to approve the first digital pill for use with the antipsychotic drug Abilify, often prescribed to treat schizophrenia, bipolar disorder and depression. The new research involved just 15 patients, all of whom had been prescribed the opioid pain drug oxycodone (OxyContin) after sustaining a fracture. However, the study participants were given a special configuration of oxycodone. The pain med was packaged together with a so-called "digital pill." This meant that each time a patient took the pain med, they ingested a gelatin capsule that contained the oxycodone as well as a radiofrequency ... Read more

Related support groups: OxyContin, Opiate Dependence, Abilify, Drug Dependence, Fracture, bone, Toxic Reactions Incl Drug and Substance Abuse, Abilify MyCite

FDA Approves Abilify MyCite (aripiprazole) Pill with Sensor to Digitally Track if Patients Have Ingested Their Medication

Posted 14 Nov 2017 by Drugs.com

November 13, 2017 – The U.S. Food and Drug Administration today approved the first drug in the U.S. with a digital ingestion tracking system. Abilify MyCite (aripiprazole tablets with sensor) has an ingestible sensor embedded in the pill that records that the medication was taken. The product is approved for the treatment of schizophrenia, acute treatment of manic and mixed episodes associated with bipolar I disorder and for use as an add-on treatment for depression in adults. The system works by sending a message from the pill’s sensor to a wearable patch. The patch transmits the information to a mobile application so that patients can track the ingestion of the medication on their smart phone. Patients can also permit their caregivers and physician to access the information through a web-based portal. “Being able to track ingestion of medications prescribed for mental illness may be ... Read more

Related support groups: Depression, Bipolar Disorder, Abilify, Schizophrenia, Aripiprazole, Abilify Maintena, Abilify Discmelt, Abilify MyCite

FDA OKs First 'Digital Pill', Abilify Mycite, That Lets Doctors Know It's Been Taken

Posted 14 Nov 2017 by Drugs.com

TUESDAY, Nov. 14, 2017 – Offering both the promise of better patient compliance with health care, but also fears of a medical "Big Brother," a newly approved "digital pill" allows physicians to track whether or not it's been ingested by patients. The U.S. Food and Drug Administration has given the nod to Abilify MyCite, for use in patients with schizophrenia, an add-on treatment for depression, and to help control episodes of either manic or "mixed" episodes for people with bipolar disorder. As explained in an FDA news release, the pill contains a sensor that communicates with a wearable patch. This patch in turn sends signals to the patients' smartphone, telling them whether or not they've taken the pill, along with the pertinent dates and times. "Patients can also permit their caregivers and physician to access the information through a web-based portal," the FDA noted – opening the ... Read more

Related support groups: Bipolar Disorder, Abilify, Schizophrenia, Mania, Schizoaffective Disorder, Aripiprazole, Abilify Maintena, Aristada, Abilify Discmelt, Abilify MyCite

'Digital Pill' Tells Doctor When Patient Takes It

Posted 14 Nov 2017 by Drugs.com

TUESDAY, Nov. 14, 2017 – The first drug designed to alert a doctor when a patient takes the medication has been approved by the U.S. Food and Drug Administration. Abilify MyCite (aripiprazole with sensor) has an embedded sensor that sends a message to a wearable patch that the medication's been taken. This allows the patient and doctor to track the medication's use via smartphone. Abilify, first approved in 2012, is now OK'd to treat schizophrenia, manic depression and bipolar disorder, the FDA said in a news release. "Being able to track ingestion of medications prescribed for mental illness may be useful for some patients," said Dr. Mitchell Mathis, director of the agency's Division of Psychiatry Products. Abilify MyCite hasn't been proven to improve patient compliance with taking medication on a prescribed schedule, the FDA stressed. And the drug shouldn't be used in an attempt to ... Read more

Related support groups: Depression, Bipolar Disorder, Abilify, Schizophrenia, Schizoaffective Disorder, Aripiprazole, Abilify Maintena, Aristada, Abilify Discmelt, Abilify MyCite

Genes May Explain Why Some Don't Respond to Bipolar Drug

Posted 8 Nov 2017 by Drugs.com

WEDNESDAY, Nov. 8, 2017 – In a finding that pulls the roots of two mental illnesses closer together, researchers say people with bipolar disorder that's resistant to the drug lithium have a high number of genes associated with schizophrenia. Since the 1950s, lithium has been widely used to treat bipolar disorder. The drug stabilizes mood swings – the highs and lows associated with the disorder – and reduces the risk of suicide. But nearly one-fourth of patients don't respond to the drug and about 30 percent have only a partial response. To learn more about why some don't respond to the treatment, researchers studied the genetics of more than 2,500 bipolar patients who were given lithium. "We found that patients clinically diagnosed with bipolar disorder who showed a poor response to lithium treatment all shared something in common: a high number of genes previously identified for ... Read more

Related support groups: Bipolar Disorder, Seroquel, Abilify, Lithium, Schizophrenia, Latuda, Mania, Risperidone, Zyprexa, Schizoaffective Disorder, Risperdal, Quetiapine, Geodon, Saphris, Seroquel XR, Olanzapine, Invega, Rexulti, Clozapine, Aripiprazole

Magnetic Brain Stimulation May Quiet 'Voices' in Schizophrenia

Posted 7 Sep 2017 by Drugs.com

THURSDAY, Sept. 7, 2017 – A therapy that stimulates a region of the brain linked to language may help quiet the hallucinatory "voices" that often plague schizophrenia patients, new research suggests. A voice hallucination "seems very real for the patient, and very disturbing," explained study author Dr. Sonia Dollfus. "The voices can be felt inside or outside the brain." Dollfus is head of the mental health department with the Hospital Center University of Caen in France. Typically, the 70 percent of schizophrenia patients who experience these voices are treated with antipsychotics, she said. Unfortunately, not all patients respond, but this new treatment may be a "very promising" alternative, she added. Dollfus noted that voice hallucinations can involve just one voice or several voices, speaking intermittently or constantly. In some cases the voices – which can be adversarial or ... Read more

Related support groups: Seroquel, Abilify, Lithium, Schizophrenia, Latuda, Risperidone, Zyprexa, Schizoaffective Disorder, Risperdal, Quetiapine, Geodon, Saphris, Seroquel XR, Olanzapine, Invega, Haldol, Rexulti, Clozapine, Aripiprazole, Haloperidol

Abilify Maintena (aripiprazole) for Extended-Release Injectable Suspension Approved by the U.S. FDA for Maintenance Monotherapy Treatment of Bipolar I Disorder

Posted 8 Aug 2017 by Drugs.com

Valby, Denmark and Tokyo, Japan, 28 July 2017 - H. Lundbeck A/S (Lundbeck) and Otsuka Pharmaceutical Co., Ltd. (Otsuka) today announced Abilify Maintena® (aripiprazole) for extended-release injectable suspension was approved by the U.S. Food and Drug Administration for the maintenance monotherapy treatment of bipolar I disorder (BP I) in adults1. Abilify Maintena is a once-monthly injectable formulation for intramuscular use created by Otsuka and has been co-developed and co-commercialized with Lundbeck. Based on phase III study data, Abilify Maintena delayed the time to recurrence of any mood episode in adult patients experiencing a manic episode at screening compared to placebo1. "Bipolar I disorder is a recurrent chronic mental illness. Abilify Maintena provides healthcare professionals (HCPs) a new treatment option for their patients who have established tolerability with oral ... Read more

Related support groups: Bipolar Disorder, Abilify, Aripiprazole, Abilify Maintena

Chronic Pain Common in Adults With Depression, Anxiety

Posted 6 Jun 2017 by Drugs.com

TUESDAY, June 6, 2017 – Chronic pain afflicts about half of adults who have anxiety or depression, a new study finds. More than 5,000 adults in Brazil diagnosed with anxiety or mood disorders such as depression and bipolar disorder were asked about other health problems. Among those with a mood disorder, half reported chronic pain; 33 percent, respiratory diseases; 10 percent, heart disease; 9 percent, arthritis; and 7 percent, diabetes. Among those with anxiety, 45 percent reported chronic pain; 30 percent, respiratory diseases; and 11 percent each for arthritis and heart disease. Adults with two or more chronic diseases had an increased risk of a mood or anxiety disorder. High blood pressure was associated with both disorders at 23 percent, according to the Columbia University study published online June 1 in the Journal of Affective Disorders. Senior author Dr. Silvia Martins said ... Read more

Related support groups: Pain, Depression, Anxiety, Generalized Anxiety Disorder, Bipolar Disorder, Anxiety and Stress, Suboxone, Tramadol, Oxycodone, Lexapro, Cymbalta, Zoloft, Effexor, Chronic Pain, Prozac, Hydrocodone, Methadone, Percocet, OxyContin, Seroquel

'Recovery-Oriented' Talk Therapy May Help Curb Schizophrenia

Posted 6 Jun 2017 by Drugs.com

TUESDAY, June 6, 2017 – A type of talk therapy may provide lasting benefits for schizophrenia patients, a new study suggests. This approach is called recovery-oriented cognitive therapy. The study of 60 patients found those who received this therapy showed major improvements compared to those who received standard treatment, said researcher Paul Grant and his colleagues at the University of Pennsylvania. Schizophrenia is a serious mental illness. People with low-functioning schizophrenia are often isolated and disengaged from the outside world, lacking any future goals. In recovery-oriented cognitive therapy, a therapist helps the patient identify goals – like getting a specific job, reconnecting with family, or living independently. The therapist then works with the patient to overcome challenges and prevent relapse. Study participants had schizophrenia or schizoaffective disorder. ... Read more

Related support groups: Seroquel, Abilify, Lithium, Schizophrenia, Latuda, Risperidone, Zyprexa, Schizoaffective Disorder, Risperdal, Quetiapine, Geodon, Saphris, Seroquel XR, Olanzapine, Invega, Haldol, Rexulti, Clozapine, Aripiprazole, Haloperidol

Nearly a Third of Drugs Hit by Safety Issues After FDA Approval

Posted 10 May 2017 by Drugs.com

WEDNESDAY, May 10, 2017 – Safety problems emerge with nearly one in three prescription drugs after they've been approved by the U.S. Food and Drug Administration, a new study reveals. Researchers examined data on drugs approved by the FDA between 2001 and 2010, with follow-up through 2017. The investigators found that 32 percent of the drugs had safety issues after approval. "That is very rarely a drug withdrawal, but more commonly a black-box warning or drug safety communication issued by the FDA to let physicians and patients know that new safety information has been determined," said study leader Dr. Joseph Ross. He is an associate professor of medicine and public health at Yale University. Of 222 drugs approved by the agency during the study period, three were withdrawn, 61 received boxed warnings and 59 prompted safety communications, the findings showed. Drugs most likely to have ... Read more

Related support groups: Seroquel, Abilify, Latuda, Risperidone, Zyprexa, Risperdal, Quetiapine, Geodon, Saphris, Seroquel XR, Olanzapine, Invega, Rexulti, Clozapine, Aripiprazole, Arginine, Clozaril, L-Arginine, Vraylar, Ziprasidone

Nursing Home Program Offers Alternatives to Antipsychotic Drugs

Posted 20 Apr 2017 by Drugs.com

THURSDAY, April 20, 2017 – Hoping to cut the use of antipsychotic drugs in nursing home residents, researchers tried training staff on new ways to meet the needs of residents with dementia. Although antipsychotics are often given to people with dementia, the drugs are only minimally effective at controlling behavioral problems and have been shown to increase the chances for stroke and death, the researchers said. "This intervention focused on treating the residents as human beings with needs, not as patients with problems," said lead author Dr. Jennifer Tjia. The new study included 93 nursing homes in Massachusetts. Staff – including nurses, nursing assistants, dietary staff and receptionists – were trained to recognize that difficult behavior by residents with dementia is a sign that they have unmet needs. The program, called OASIS, provides employees with the knowledge, skills and ... Read more

Related support groups: Seroquel, Abilify, Latuda, Risperidone, Zyprexa, Dementia, Risperdal, Quetiapine, Geodon, Saphris, Seroquel XR, Olanzapine, Alzheimer's Disease, Invega, Rexulti, Clozapine, Aripiprazole, Clozaril, Vraylar, Mild Cognitive Impairment

FDA Warns Against Bogus Autism 'Cures'

Posted 12 Apr 2017 by Drugs.com

WEDNESDAY, April 12, 2017 – Don't fall for products claiming to cure autism, the U.S. Food and Drug Administration warns. There's no cure for the neurodevelopmental disorder, the agency said. Yet bogus "cures" and therapies abound – from toxin removal to raw camel milk. Some of these fraudulent treatments could be harmful, and should be avoided, the agency said Wednesday. Among them: chelation therapies, hyperbaric oxygen therapy and detoxifying clay baths. Autism spectrum disorder affects about 1 in 68 children in the United States, boys far more often than girls. "Autism varies widely in severity and symptoms. Existing autism therapies and interventions are designed to address specific symptoms and can bring about improvement," FDA pediatrician Dr. Amy Taylor said in an agency news release. Children with an autism spectrum disorder have difficulties with social interaction and ... Read more

Related support groups: Abilify, Risperidone, Risperdal, Autism, Aripiprazole, Asperger Syndrome, Risperdal Consta, Abilify Maintena, Risperdal M-Tab, Abilify Discmelt, Aristada

Patients Often Reject Drug-Only Psychiatric Treatment

Posted 6 Mar 2017 by Drugs.com

MONDAY, March 6, 2017 – Mental health patients are more likely to reject treatment if it involves only drugs, a new study finds. Some experts believe talk therapy should be the first treatment option for many mental health disorders. The new finding – from a review of 186 prior studies – supports that stance, the researchers said. "Patients often desire an opportunity to talk with and work through their problems with a caring individual who might be able to help them better face their emotional experiences," said study co-author Roger Greenberg. He's a professor of psychology at the State University of New York's Upstate Medical University. Greenberg and his colleagues analyzed 186 studies of patients who sought help for mental health conditions. Overall, the average treatment refusal rate was more than 8 percent. Patients offered drug therapy alone were almost twice as likely to ... Read more

Related support groups: Depression, Anxiety, Generalized Anxiety Disorder, Panic Disorder, Bipolar Disorder, Anxiety and Stress, Lexapro, Cymbalta, Zoloft, Effexor, Prozac, Seroquel, Major Depressive Disorder, Celexa, Paxil, Citalopram, Post Traumatic Stress Disorder, Abilify, Sertraline, Pristiq

Little Weight Gain in Pregnancy Tied to Schizophrenia Risk in Kids: Study

Posted 23 Feb 2017 by Drugs.com

WEDNESDAY, Feb. 22, 2017 – Gaining too little weight during pregnancy may increase the odds that a child will develop schizophrenia later in life, Swedish researchers suggest. Past research has shown that pregnant women in areas of famine are more likely to have children who suffer from mental disorders, including schizophrenia. The new study found a 30 percent increased risk for schizophrenia in children of underweight women in an industrialized country. "Even in a wealthy, well-fed population like Sweden, there are still mothers unable to meet the nutritional requirements for safe pregnancies," lead researcher Euan Mackay said. Mackay is a research assistant at the Karolinska Institute's division of epidemiology of mental health in Stockholm. Mackay cautioned that these findings cannot prove that women who don't gain enough weight during pregnancy are putting their child at risk for ... Read more

Related support groups: Seroquel, Abilify, Weight Loss, Schizophrenia, Latuda, Risperidone, Zyprexa, Schizoaffective Disorder, Risperdal, Quetiapine, Geodon, Saphris, Seroquel XR, Psychosis, Olanzapine, Invega, Delivery, Rexulti, Clozapine, Aripiprazole

Many Seniors Take Multiple Meds That Can Affect the Brain

Posted 13 Feb 2017 by Drugs.com

MONDAY, Feb. 13, 2017 – There has been a sharp rise in the number of American seniors who take three or more medications that affect their brains, a new study reveals. The study looked at seniors' use of opioid painkillers, antidepressants, tranquilizers and antipsychotic drugs. A review of U.S. Centers for Disease Control and Prevention data showed that the use of these drugs in people over 65 more than doubled from 2004 to 2013. The researchers estimated that approximately 3.7 million doctor visits a year are by seniors taking three or more of these drugs. The largest increase was seen among seniors in rural areas. There, the use of these drugs more than tripled. The spike in the combined use of drugs that act on the central nervous system is cause for concern because it can lead to falls and resulting injuries, affect driving ability, and cause memory and thinking problems, the ... Read more

Related support groups: Xanax, Tramadol, Oxycodone, Lexapro, Cymbalta, Zoloft, Effexor, Prozac, Wellbutrin, Hydrocodone, Methadone, OxyContin, Seroquel, Celexa, Paxil, Citalopram, Fentanyl, Abilify, Morphine, Valium

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Bipolar Disorder, Depression, Agitated State, Schizoaffective Disorder, Autism, Major Depressive Disorder, Schizophrenia

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