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Could a Clot-Busting Drug Help Treat a 'Bleeding' Stroke?

Posted 18 Feb 2016 by Drugs.com

THURSDAY, Feb. 18, 2016 – In what one expert called a "counterintuitive" finding, research suggests that the powerful clot-busting drug known as tPA might help patients suffering a hemorrhagic ("bleeding") stroke. According to the American Stroke Association, only about 15 percent of strokes are caused by runaway bleeding in the brain; the other 85 percent are caused by a clot. And while it makes sense to use the clot-busting tissue plasminogen activator (tPA) to break up a brain clot, it would seem counterproductive to use the same drug in the case of a bleeding stroke. However, two new studies to be presented Thursday at the stroke association's annual meeting in Los Angeles suggest that tPA may, indeed, have a role to play in the treatment of a bleeding stroke. Both studies were funded by the U.S. National Institutes of Neurological Disorders and Stroke. One study involved 500 ... Read more

Related support groups: Blood Disorders, Bleeding Disorder, Ischemic Stroke, Transient Ischemic Attack, Blood Transfusion, Ischemic Stroke - Prophylaxis, Thromboembolic Stroke Prophylaxis, Diagnosis and Investigation, Intracranial Hemorrhage, Streptokinase, Urokinase, Abbokinase, Kabikinase, Streptase, Abbokinase Open-Cath, Kinlytic

For Stroke Patients, Temporary Easing of Symptoms Can Be Deceiving

Posted 18 Feb 2016 by Drugs.com

WEDNESDAY, Feb. 17, 2016 – A quick improvement in symptoms before a stroke patient arrives at the hospital doesn't necessarily mean a better outcome, a new study finds. "Patients with very early rapid neurological improvement when first examined at the hospital still need to be considered for therapy to dissolve blood clots, given the high rate of unfavorable outcome," study author Dr. Clotilde Balucani said in a news release from the American Stroke Association (ASA). Her team was slated to present the findings on Wednesday at the association's annual meeting, in Los Angeles. The study included 1,700 stroke patients, average age 70, who were assessed for symptoms such as facial droop, difficulties with speech, weak hand grip and arm strength. However, about a fifth of the patients showed a rapid improvement of stroke symptoms like these. Those patients were less likely to have high ... Read more

Related support groups: Ischemic Stroke, Transient Ischemic Attack, Ischemic Stroke - Prophylaxis, Diagnosis and Investigation, Streptokinase, Urokinase, Body Imaging, Computed Tomography, Head Imaging, Abbokinase, Kabikinase, Streptase, Abbokinase Open-Cath, Kinlytic

More Evidence That Time-to-Treatment Is Crucial for Stroke

Posted 21 Dec 2015 by Drugs.com

MONDAY, Dec. 21, 2015 – Stroke patients have worse outcomes when delays occur in restoring blood flow to the brain, a new study says. Dutch researchers looked at 500 people who suffered a stroke caused by blocked blood flow to the brain – what's known as an ischemic stroke, the most common form. About half of the patients received intra-arterial treatment (IAT), which involves inserting a catheter into an artery to either remove the clot, to deliver clot-busting drugs near the site of the blockage, or both. The other patients did not receive IAT. The study found that the average amount of time needed between the onset of a stroke and the moment the patient first received the catheter was about four hours and 20 minutes, and the average time it took for blood flow to be restored to the brain was five hours and 40 minutes. There was a 6 percent lower chance of a good outcome for ... Read more

Related support groups: Ischemic Stroke, Transient Ischemic Attack, Ischemic Stroke - Prophylaxis, Streptokinase, Urokinase, Abbokinase, Kabikinase, Streptase, Abbokinase Open-Cath, Kinlytic

More Progress Needed To Get Stroke Patients Rapid Care

Posted 31 Jul 2015 by Drugs.com

FRIDAY, July 31, 2015 – Stroke victims still aren't getting treated soon enough, a new study suggests. Treating strokes quickly is critical, because the more time that elapses, the less effective stroke treatment may be, the researchers explained. A number of factors have reduced the time it takes stroke patients to get treatment. These include greater public awareness, better emergency dispatch procedures and improvements in hospital stroke units, the researchers said. But, delays in transporting stroke patients from regional hospitals to comprehensive stroke centers are still common, the team found. "Stroke requires a multi-disciplinary team that engages in a nuanced chain of events leading to treatment, and efficient and prompt patient transport via emergency medical services [EMS] is a significant link in the process," study author Dr. Michael Froehler, neurointerventionalist at ... Read more

Related support groups: Ischemic Stroke, Transient Ischemic Attack, Ischemic Stroke - Prophylaxis, Intracranial Hemorrhage, Activase, Streptokinase, TNKase, Cathflo Activase, Urokinase, Alteplase, Retavase, Abbokinase, Reteplase, Streptase, Tenecteplase, Eminase, Kinlytic, Anistreplase, Retavase Half-Kit, Abbokinase Open-Cath

Wide Variations Seen in U.S. Stroke Care

Posted 7 Jul 2015 by Drugs.com

TUESDAY, July 7, 2015 – Americans' odds of receiving a drug that can halt strokes in progress may vary widely depending on their ZIP codes, a new study finds. Experts said the findings, reported in the July issue of the journal Stroke, help verify what everyone has suspected: There are disparities in emergency stroke care across the United States, specifically in the use of a clot-busting drug called tissue plasminogen activator, or tPA. And the magnitude of the disparities was "striking," said senior researcher Dr. James Burke, of the University of Michigan in Ann Arbor. In 20 percent of hospital markets, not a single stroke patient received tPA over four years, Burke's team found. In others, up to 14 percent of stroke patients received the drug. The big question is: Why? "We really don't know what's driving this," Burke said. The hospital markets that most often gave tPA were ... Read more

Related support groups: Aspirin, Plavix, Ischemic Stroke, Clopidogrel, Transient Ischemic Attack, Effient, Aggrenox, Brilinta, Ischemic Stroke - Prophylaxis, Ecotrin, Cilostazol, Pletal, Bayer Aspirin, Thromboembolic Stroke Prophylaxis, Dipyridamole, Prasugrel, Ticagrelor, Persantine, Bufferin, Activase

Expert Tips to Detect Early Warning Signs of Stroke

Posted 11 May 2015 by Drugs.com

SUNDAY, May 10, 2015 – Prompt treatment of stroke is key to preventing death and disability, but not everyone knows how to quickly identify the early warning signs of stroke. "Today, thanks to early detection, aggressive treatment and new intervention therapies, more stroke patients than ever are returning to normal life with limited to no disability," said Dr. Stanley Tuhrim, director of the Stroke Center at Mount Sinai Hospital in New York City. "Despite these accomplishments, it is clear that there is still much more work to be done to reduce the burden of stroke in our community. The challenge remains to educate as many people as possible about stroke's earliest warning signs and symptoms, so patients can get the immediate treatment they need," he said in a hospital news release. Stroke is a leading cause of long-term disability and the fifth leading cause of death in the United ... Read more

Related support groups: Atrial Fibrillation, Ischemic Stroke, Transient Ischemic Attack, Ischemic Stroke - Prophylaxis, Cardiovascular Risk Reduction, Cardiovascular Conditions and Disorders, Intracranial Hemorrhage, Activase, Streptokinase, Alteplase, TNKase, Cathflo Activase, Urokinase, Retavase, Abbokinase, Streptase, Reteplase, Eminase, Tenecteplase, Kinlytic

Pros, Cons to Dissolving Lung Clots: Study

Posted 17 Jun 2014 by Drugs.com

TUESDAY, June 17, 2014 – Drugs used to break up blood clots in the lungs may lower the risk of death, but they also increase the risk of bleeding, a new study finds. Researchers analyzed data from 16 trials involving use of clot-busting drugs called thrombolytics to treat life-threatening clots in the lungs (pulmonary embolism). Despite the drugs' apparent life-saving benefits, the risk of major bleeding, particularly in the brain, remains a concern, experts say. "The study advances our understanding, but is not enough to provide a definitive recommendation for use in all patients," said Dr. Joshua Beckman, director of the cardiovascular fellowship program at Brigham and Women's Hospital in Boston, who was not involved in the study. The evidence suggests that clot-busting therapy has merit but needs more study to refine the method by which it is given and to whom, added Beckman. What's ... Read more

Related support groups: Xarelto, Pradaxa, Pulmonary Embolism, Heparin, Rivaroxaban, Arixtra, Hep-Pak, Fondaparinux, Activase, Dabigatran, Streptokinase, Cathflo Activase, Alteplase, Heparin Sodium, Urokinase, Abbokinase, Hep-Pak CVC, Kabikinase, Arixtra 10 mg/dose, Streptase

Every Minute Counts for Stroke Victims, Study Confirms

Posted 18 Jun 2013 by Drugs.com

TUESDAY, June 18 – For stroke victims, 15 minutes can mean the difference between life and death, a new study finds. Rapid treatment with a clot-dissolving drug reduces stroke patients' risk of in-hospital death and increases their chances of being able to walk and return home when they leave the hospital, according to the study, published in the June 19 issue of the Journal of the American Medical Association. "These findings support intensive efforts to accelerate patient presentation and to streamline regional and hospital systems of acute stroke care to compress [onset to treatment] times," Dr. Jeffrey Saver, of the David Geffen School of Medicine at the University of California, Los Angeles, and colleagues said in a journal news release. Researchers examined data from more than 58,000 patients who suffered an ischemic stroke (in which blood flow to the brain is blocked) and were ... Read more

Related support groups: Ischemic Stroke, Activase, Streptokinase, Urokinase, TNKase, Cathflo Activase, Alteplase, Retavase, Abbokinase, Tenecteplase, Streptase, Eminase, Anistreplase, Kinlytic, Retavase Half-Kit, Abbokinase Open-Cath, Kabikinase, Reteplase

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Thrombotic / Thromboembolic Disorder, Pulmonary Embolism, Myocardial Infarction, Heart Attack, Deep Vein Thrombosis (DVT), Deep Vein Thrombosis

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