... spent 3 weeks, because the Clindamycin I got for a cellulitis infection triggered SJ. Red, exquisitely painful skin that peeled off my arms and shoulders. My BP soared to 204/84. No blistering to speak of. But 4 years ago, while in the hospital for the same issue, I was given vancomycin. Within 48 hours my skin started to blister and peel off in sheets. My BP was just as high, and my kidneys went nuts. I had diabetes INSIPIDUS, with uncontrolled thirst and urinating. This was, of course, toxic epidermal necrolysis, the extreme end of the SJ spectrum. I also think I had a third SJ attack, caused by the Zyvox antibiotic I was taking at home. It was another "dry peel" but there were a few tiny blisters. This was the 1st time, BTW, the TEN was the 2nd, and the one a few weeks ago was the 3rd time. I am retired and having all sorts of bad side-effects with many medications
I didn't even know such a thing existed. However I'm no stranger to cellulitis (always right leg, usually restricted to below the knee except for the last time where the infection got into my veins and I had a line of infection running up to my groin. they said if I had waited 24 hours longer... well, I wouldn't be here typing this).
The IV antibiotics they use for the first week is always Cefazolin Sodium 1000mg twice daily but the second week this time they gave me Clindamycin 150mg, 3 times daily and thinking about it now I got tiny red blisters too. Week 3, I had the snake skin; and I have to say it was a first for me peeling off strips of skin inches long and then having to break the skin away from adjacent live tissue (soles of my feet were not affected badly) to prevent it from peeling away live tissue and causing bleeding. It never occurred to me that the antibiotic was responsible. In hindsight not only was Clindamycin not very effective, gave me a foul medicine taste in my mouth, allowed a really stubborn fungus get established on my face AND now you say the blisters came from it too? Next time for the orals I'll ask for Staphylex 500, 4 times daily again which is what they have used in the past and I have found it very effective as the week 2 oral antibiotic and completely without side effects in me.
Thanks for sharing your story as I found it educational; I'm very sorry that all I could offer was a name of one antibiotic that just worked as advertised.
Good luck and take care, Steve.
- Clindamycin Information for Consumers
- Clindamycin Information for Healthcare Professionals (includes dosage details)
- Side Effects of Clindamycin (detailed)
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