How does one begin treating their depression and anxiety with Niacin while they are on antidepressants? I want to begin taking Niacin but I currently take .60 mgs a day of Cymbalta and up to 2 mgs a day of Xanax. How would I incorporate Niacin into this. Do I stop taking the other meds all together? If so what about the severe withdrawals that occur with both of these medications. Or do I start the Niacin along with these meds and wean off the meds as I increase the Niacin? I would like to start taking Niacin asap so any and all advice would be greatly appreciated.