5 yrs ago I 1st tried it and had some results. After about 2 yrs it just stopped the little help I was getting. Over this 31 yrs I have been on practically everything for Crohnss and a lor of off label meds with minimal results. 4 bowel resections and many hospitalizations later I am still looking for relief. Can any one w/ Crohns who has used the Pen tell me how it worked for you? My doc wants me to try again b/c we are basically at the end of the line. All advice welcome, thanks, Chelle