I do not have a history of pancreatitis or gallstones and neither does my family. I may just be a hypochondriac. I feel pain around my middle from time to time, but it is not severe or radiating. I'm wondering if that could just be the indigestion side effect or nerves, but I am not sure since this is new to me. Does anyone else have any insight or background into this and how they feel after taking it the first time?