The doc told us to expect sleepy and grumpy, but my son (age 21) is complaining of anger and pain, which he did not feel while on prolixin (fluphenazine). Voices seem to have stopped; constant voices, sometimes disturbing, were a problem with prolixin. Is the anger a common side effect when starting clozapine? What can I do to help the anger subside? Just picked up new Rx to take 50-100mg 2x day. Perhaps an increased dose of 100mg 2x day will help. My fear is that my son will refuse to take the next dose.