I am asthmatic and have been given solumedrol with antibiotics for upper respiratory infections. This is the third time in one year that this has lead to severe shortness of breath without any asthma symptoms. The other two times I was hospitalized, had cardiac studies, which where normal, and got gradually better without explanations after getting off steroids. I am just starting to wonder if the solumedrol is the the problem because I don't recall having SOB before the medication.