I'm taking Zapain and Amytriptalin (think that's how it's spelt) for severe headaches after a brain hemeorage.
So you are taking Acetaminophen plus Codeine and Amitriptyline (which is a tricyclic antidepressant) and want to add St John's Wort to the mix (an OTC herbal antidepressant). The drug interactions checker does not cover herbal OTC supplements. You need to ask your doctor for advice, sorry, mixing antidepressant medications is probably best left to the experts.
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