In the Sinemet information guide, it says this:
""Talk with your doctor if your symptoms do not improve after a few weeks of treatment. Also tell your doctor if the effects of this medication seem to wear off quickly in between doses.""
I would say it could take up to a few weeks, but hopefully not that long.
- Sinemet Information for Consumers
- Sinemet Information for Healthcare Professionals (includes dosage details)
- Side Effects of Sinemet (detailed)
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