Hi all, I have had Psoriatic Arthritis for 15 1/2 years now and when I was first diagnosed I was put on Methotrexate. After a few years Sulfasalazine was added to help. 2 years ago I stopped the Methotrexate and started on Simponi. Is anyone on here taking Simponi together with Sulfasalazine or suffers with PsA??
Hello ... I just had my second injection of Simponi. I am taking MTX with it. I would strongly urge you yo stsy with MTX or at least monitor your joints RIGOROUSLY for several years because:
a) I started MTX in early 1977 when my sed rate was over 100; I have Reiter's Syndrome; dosage was 27 mg/week
b) I took Sulfasalazine with MTX, Indocin (and its clones),
c) when my liver tests forced me off MTX for more than four weeks I felt increasing pain and saw increased redness and swelling
d) I stopped MTX in Dec 2000 after several Vioxx "episodes", switched to Enbrel until early 2011
e) restarted MTX because I was getting SLOWLY worse; I failed to notice and the health plan failed as well:
1) replacement of left MCP in 2004,
2) follow-up operation in 2010 to remove 1/4 inch of "build-up" around right heel and Achilles tendon (doc left tendon alone, as separation & re-attachment was not worth it (has anyone had that type of operation?)
3) both TMJs replaced Nov 2012 (yes, 2 yrs ago next week)
4) repeated swollen & painful joints in feet, increased MTX to .8mg/week subcu
5) although the TMJ operation brought instant relief to my upper back & neck, the stiffness re-appeared within a year (but it was great while it lasted)
Since then, while still on MTX, I switched from Enbrel to:
Humira for several months (no change),
Otezla for 8 weeks before depression reared its ugly head (not suicidal, but just a feeling that my life & relationships with people were easily replaceable ... the simple cog in the machine), toes became so swollen that blood did not flow sufficiently, blisters at end of toes increased, mini-cuts created two separate instances of IV anti-biotics in the doc's office,
Took prednisone for six weeks until I realized that screaming loudly at my wonderful dog so that she would return to my room several minutes later with her tail between her legs
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