I was on Sprycel 100 mg, then lowered to 70 mg, now back to 100 mg/day because my last BMB showed numbers going back up. My doctor says I have a rare form with some DNA changes occuring. Having multiple side effects, anorexia, wt. loss, hair loss, leg pain, headaches, severe fatigue, trouble sleeping, short of breath, no energy, tremors... almost like I have the flu all the time. Does anyone else have these many side effects, or might it be the "rare" thing my doctor has referred to?? don't quite understand what the specifics are yet. Oncologist just informed me of this last week.