I have been on it for 6 months and doing well with 1 pill every 12-15 hours and 4 oxycodone for BT limit 4 per day. I'm a 61 yr. female 180lbs and this is the best i have felt in years. All movement has improved and dosage has remained the same for 6 months, Do I have to worry about coming off of it. My family is concerned but my Dr. feels that it is safe and that I don't need as many procedures or injections to get me out of pain.