I have chronic, severe pain, 24/7, after two failed spinal cord surgeries, within the last four years. I have debilitating depression, with manageable anxiety, due to this condition. I have used Prozac, Paxil, Zoloft, and am currently taking 40 mg. Celexa. I have been on this for 5 years and my depression is now at breaking point. I am excited, after reading the feedback for Viibryd to request that my doctor start me on Viibryd. I am concerned, however, that I will also be transitioning from Oxycontin, 40 mg. 3X day to Neurontin (not sure on doseage yet) at the same time. Should I make only ONE change to my meds and then begin the other transition? I'm a bit concerned how I will differentiate between side effects with two major changes in one month. Has anyone else experienced chronic pain med changes with SSRI's? Any feedback would be most appreciated. Thanks you and good luck to all here!