About 3 years ago my husband had a life threatening allergic reaction to Bactrim that was prescribed to him for a pilonidal cyst that had become infected. He had a high fever, a red rash all over his body, extreme weight loss, and acute liver failure. He became delirious and wasn't making sense when he talked as well as fits of rage. The doctors said if he had waited another 48 hours to come in he would have died. After he recovered he completely changed. He can't remember anything and has become short tempered. I'm worried that the reaction has caused permanent damage to his brain. Is this possible? What can we do?