... know. What strength I need. I was misinformed about the strengths available so I misinformed. My Dr. Saying 100 and 150. He gave me a SCRIPT for 150. When I called several CVS pharmacies one told me it was back ordered meaning they couldn't even order it another said they would order it on Monday and one told me they had 250mg. In stock so I asked the Dr to please call that in which he did. But now I don't know how much to take? I wasn't able to speak to the Dr. And he doesn't return calls. I just saw him today. Any advice on what the normal dosage would be for major depression and anxiety. I've been on Cymbalta 60mg. But it wasn't doing the trick. I've tried so many types (for approximately 5 yrs.) that haven't worked