... Rheumatoid arthritis,Etodolac 600 ER,Cymbalta 60mg,Tramadol 50mg and Plaqunil. Has anyone gotten toxic on these? According to all the literature they really are contradicted for one another. Why I was given all of these I can't guess. How long does it take to come off of these meds and return to normal? I have been about a week. Will it take longer?