I am taking 300mg of Wellbutrin XL daily along with 0.5mg of Klonopin. I am seeking recommendations on which of antidepressant to combine with the Wellbutrin. Which SSRI has the least side effects with Wellbutrin? Wellbutrin is the first antidepressant that has not cause me side effects. My depression continues, so that is why I am asking you folks. From another thread I read that Zoloft works better that Prozac? Does anyone have any thoughts. Thank you in advance for your reply.