The dose of dihydrocodeine is 120mg twice a day.the amitriptyline dose is currently 20mg at night.I have osteoarthritis which is not being controlled well with my current medication
Can you please specify which dihydrocodeine so as to an interaction check?
Tramadol and Amitriptyline need to be closely monitored.
Their is a low risk of seizures with Tramadol.
The two may cause an increase in Serotonin levels which can lead to symptoms that may require medical attention.
I would double check with the physician or pharmacist...
Especially if you are elderly or have history of brain disease.
Hi, this is what the interactions checker says:
Ignore the guaifenesin following on from the Dihydrocodeine, it isn't featured in the interaction report
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