Hi, mulder! There is a risk of a condition known as serotonin syndrome, but it's extremely rare and doctors commonly prescribe antidepressants from different classes (Effexor is an SSNI and Celexa is an SSRI) as they affect different neurotransmitters. Just be sure to work closely with your doctor.
This is from the Interactions Checker at the top of this page:
Best wishes, WCV
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