I have had bouts of depression for many years. Lexapro was a God send. Recently, I was prescribed 30mg of Vyvanse to be taken in the morning. I stopped taking the Lexapro (without doctors orders- a medical friend said I shouldn't take them together). Instead of contacting my doctor, I chose to listen to a friend. 2 months later my depression is off the charts. I did contact my doctor this morning to discuss my meds. My appointment is 1 1/2 weeks away. My question is: if I take Vyvanse in the morning, is it safe to take Lexapro in the afternoon or early evening?