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Is rinofed safe in lactation?

Responses (1)

masso 21 Nov 2013

Brand name: Rinofed.

Generic Name:
Triprolidine hydrochloride, pseudoephedrine hydrochloride and guaiphenesin.

Pseudoephedrine / triprolidine Breastfeeding Warnings

Three mothers given pseudoephedrine demonstrated milk concentrations consistently higher than plasma concentrations. Maximum milk concentrations were reached at 1 to 1.5 hours after dosing. In one woman, the milk:plasma concentration ratio at 1, 3, and 12 hours was 3.3, 3.9, and 2.6. The authors calculated that 1000 mL of breast milk consumed over 24 hours would provide an infant with 0.25 to 0.33 mg of pseudoephedrine, or 0.5% to 0.7% of the dose ingested by the mother.

There are no data on the excretion of pseudoephedrine-triprolidine into human milk. Pseudoephedrine is excreted into human milk. The effects in the nursing infant are unknown. The American Academy of Pediatrics considers pseudoephedrine to be compatible with breast-feeding.


I suggest you contact your Dr. and ask her/him to asses you with regards to the benefits outweighing the potential risks involved.

Take care,

jindiyajohn 21 Nov 2013

thank you so much

masso 22 Nov 2013

You are welcome.- free discount card

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