een on doses from 15-60mgs with 30 being the best I think. It helps get me to about 40% better and I get no SE's other than terrible weight gain (like 60lbs in a year) and I was kinda overweight to start with. I asked to be taken off it for that reason and was put on Wellbutrin XL 150mgs then 300mgs which caused me lots of anxiety (already a severe problem) so I was put on the SR version 100mgs BID then 150 BID without anxiety and it helps with motivation but not good enough. I've tried almost everything and nothing works like Remeron so I'm wondering if I took 30mgs of Remeron plus 150 Wellbutrin BID would that be too much Norepinephrine for somebody who also has severe GAD? I also take 60mgs of Latuda, 2mgs of Klonopin BID and 125mgs of Nuvigil once in a while. Also is their anything I can take to prevent weight gain? I already exercise fairly intensely
Remeron plus Wellbutrin? Remeron has been the antidepressant that has worked the best and I've been?
- 10 Feb 2018 by luke uno
- 8 January 2019 (6 weeks ago)
- remeron, wellbutrin, depression, obesity, major depressive disorder, weight, dosage, antidepressant, antidepressants
I tried this combination recently and had similar results. My anxiety went up so bad depression became a second thought. I have been taking Remeron for a while though, for sleep, and it works well in that regard, just not with Wellbutrin, for me. I’m taking Cymbalta now, with great results, but have read it can cause weight gain, tho it hasn’t so far.
I’ve never tried Latuda. Klonopin was pretty good for anxiety in my experience but at doses higher than 3 mg/day it really shut me down. I’ve never taken Nuvigil, but have tried Provigil, but it made me really nauseous, which sucked, because it was helpful otherwise (I was on late shift work at the time).
There are meds I’ve read about to help with weight gain. Like there is a new Wellbutrin/Naltrexone combo drug for weight loss, but I’ve never tried it.
I wish you the best in your quest!
I’ve been on Wellbutrin XL at 450 mg/d for about 2 years now. Thought it wasn’t working but when I tried reducing the dose to 300 mg/d, I started feeling extremely depressed.
About 8 months ago, due to an extremely stressful personal situation, I started getting severe anxiety / panic attacks. My heart rate would intermittently stay above 100 bpm for many hours and blood pressure would go as high as 195/100 during those episodes. My lower legs have also been numb.
My family doctor prescribed 2 x 0.5 mg/d of Klonopin on top of the Wellbutrin XL. The Klonopin got my heart rate below 85 bpm and BP to normal. Only thing with the Klonopin, if I take it late in the day, I snore really bad. Klonopin also seems to delay or prevent orgasm.
With my personal situation worsening, a psychiatrist started me on 15 mg/d of Remeron about 4 days ago. So I’m now on 450 mg/d Wellbutrin XL, 2 x 0.5 mg/d Klonopin and 15 mg/d Remeron.
Only side effects I’m seeing are dry mouth and fatigue. While I seem to sleep well for most of the night, I wake-sleep-wake-sleep between 5am-7am.
While it will take another few weeks to see the full benefit of the Remeron, leg numbness seems to have been somewhat less. And for some reason, I’ve been waking up with a boner every morning. :) Something that hasn’t happened for a while.
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
Updated 9 Jun 2014 • 1 answer
Updated 16 Feb 2017 • 7 answers
Updated 27 Aug 2017 • 3 answers
Updated 21 Aug 2018 • 1 answer
Updated 25 Oct 2018 • 3 answers