... emotional, its like I have no control over my emotions at all and I'm not my normal self. I have night sweats, hot flashes, fatigue, nausea also going on. When I do start feeling overwhelmed with emotion , it makes me want to withdraw at times. Especially because I feel people around me don't understand how the medication is making me feel. I feel that sometimes people just think I'm being dramatic. Ive dealt with depression in my early teens, and have been fine up until a few weeks ago (I'm 31 now). Does anyone else ever feel this way while on Lupron and how long do these side effects typically last?