... been on effexor 37.5 for about 2 weeks. Headaches sleep all the time and just irritated. I have severe panic disorder ptsd lupus and severe depression. Switch to effexor from zoloft due to weight gain. Anyways. I stopped taking it last night. Brain zaps, sweating, just feel like im in outer space. How long will this last?? I was on paxil many years ago and experienced the same crap but i took paxil for 3 years.. I just want to feel normal as i am a mother of 3. My youngest is 15 months and i cant keep feeling this way!! No way would i have taken this crap if i would have known i would experience all of this!!